Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | REN_E2F1_TARGETS |
| Enrichment Score (ES) | -0.65738434 |
| Normalized Enrichment Score (NES) | -1.8631557 |
| Nominal p-value | 0.0020408162 |
| FDR q-value | 0.025594331 |
| FWER p-Value | 0.607 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2162 | 0.101 | -0.1285 | No |
| 2 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 2376 | 0.093 | -0.1136 | No |
| 3 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | -0.1769 | No |
| 4 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | -0.2095 | No |
| 5 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.2819 | No |
| 6 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 6089 | 0.003 | -0.3503 | No |
| 7 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 6851 | -0.010 | -0.4042 | No |
| 8 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 7607 | -0.024 | -0.4530 | No |
| 9 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | -0.5661 | No |
| 10 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 9536 | -0.064 | -0.5563 | No |
| 11 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 9665 | -0.067 | -0.5435 | No |
| 12 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11183 | -0.116 | -0.6188 | Yes |
| 13 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11410 | -0.125 | -0.5939 | Yes |
| 14 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.5543 | Yes |
| 15 | CALR | CALR Entrez, Source | calreticulin | 11620 | -0.135 | -0.5221 | Yes |
| 16 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11931 | -0.152 | -0.4946 | Yes |
| 17 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.4492 | Yes |
| 18 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12178 | -0.170 | -0.4028 | Yes |
| 19 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.3495 | Yes |
| 20 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.3087 | Yes |
| 21 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2341 | Yes |
| 22 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.1480 | Yes |
| 23 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13274 | -0.526 | 0.0051 | Yes |
