Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | REOVIRUS_HEK293_UP |
| Enrichment Score (ES) | -0.36244217 |
| Normalized Enrichment Score (NES) | -1.4139519 |
| Nominal p-value | 0.021680217 |
| FDR q-value | 0.2825525 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 25 | 0.995 | 0.0557 | No |
| 2 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.1062 | No |
| 3 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 127 | 0.610 | 0.1348 | No |
| 4 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.1553 | No |
| 5 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 273 | 0.421 | 0.1755 | No |
| 6 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 565 | 0.265 | 0.1688 | No |
| 7 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 647 | 0.246 | 0.1769 | No |
| 8 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 899 | 0.196 | 0.1693 | No |
| 9 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 1051 | 0.177 | 0.1681 | No |
| 10 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 1062 | 0.175 | 0.1774 | No |
| 11 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.1710 | No |
| 12 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 1427 | 0.140 | 0.1671 | No |
| 13 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 1722 | 0.122 | 0.1519 | No |
| 14 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 2035 | 0.106 | 0.1344 | No |
| 15 | PREI3 | PREI3 Entrez, Source | preimplantation protein 3 | 2521 | 0.087 | 0.1028 | No |
| 16 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 3210 | 0.065 | 0.0545 | No |
| 17 | BET1 | BET1 Entrez, Source | BET1 homolog (S. cerevisiae) | 3428 | 0.060 | 0.0416 | No |
| 18 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 3431 | 0.060 | 0.0449 | No |
| 19 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 3472 | 0.058 | 0.0452 | No |
| 20 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 3623 | 0.054 | 0.0370 | No |
| 21 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 3704 | 0.052 | 0.0340 | No |
| 22 | BCL10 | BCL10 Entrez, Source | B-cell CLL/lymphoma 10 | 3730 | 0.051 | 0.0351 | No |
| 23 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 3758 | 0.051 | 0.0360 | No |
| 24 | TRPC1 | TRPC1 Entrez, Source | transient receptor potential cation channel, subfamily C, member 1 | 4033 | 0.044 | 0.0178 | No |
| 25 | UBE1C | UBE1C Entrez, Source | ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) | 4065 | 0.043 | 0.0179 | No |
| 26 | TDRD7 | TDRD7 Entrez, Source | tudor domain containing 7 | 4220 | 0.039 | 0.0086 | No |
| 27 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 4230 | 0.039 | 0.0101 | No |
| 28 | PITPNB | PITPNB Entrez, Source | phosphatidylinositol transfer protein, beta | 4399 | 0.036 | -0.0005 | No |
| 29 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 4502 | 0.034 | -0.0063 | No |
| 30 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 4606 | 0.032 | -0.0122 | No |
| 31 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 5381 | 0.017 | -0.0697 | No |
| 32 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 5384 | 0.017 | -0.0689 | No |
| 33 | KLF6 | KLF6 Entrez, Source | Kruppel-like factor 6 | 5447 | 0.016 | -0.0727 | No |
| 34 | CLK1 | CLK1 Entrez, Source | CDC-like kinase 1 | 5504 | 0.015 | -0.0761 | No |
| 35 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 5592 | 0.013 | -0.0819 | No |
| 36 | PDE4D | PDE4D Entrez, Source | phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) | 5890 | 0.007 | -0.1039 | No |
| 37 | RCHY1 | RCHY1 Entrez, Source | ring finger and CHY zinc finger domain containing 1 | 5935 | 0.006 | -0.1069 | No |
| 38 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 5982 | 0.005 | -0.1101 | No |
| 39 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 6082 | 0.004 | -0.1173 | No |
| 40 | SHOC2 | SHOC2 Entrez, Source | soc-2 suppressor of clear homolog (C. elegans) | 6249 | 0.001 | -0.1299 | No |
| 41 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6268 | 0.000 | -0.1312 | No |
| 42 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 6393 | -0.002 | -0.1405 | No |
| 43 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 6484 | -0.003 | -0.1471 | No |
| 44 | TAC1 | TAC1 Entrez, Source | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | 6693 | -0.007 | -0.1624 | No |
| 45 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.1622 | No |
| 46 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 6918 | -0.011 | -0.1783 | No |
| 47 | SNRK | SNRK Entrez, Source | SNF related kinase | 6919 | -0.011 | -0.1776 | No |
| 48 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 7518 | -0.022 | -0.2216 | No |
| 49 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 7918 | -0.030 | -0.2500 | No |
| 50 | TADA2L | TADA2L Entrez, Source | transcriptional adaptor 2 (ADA2 homolog, yeast)-like | 7931 | -0.030 | -0.2492 | No |
| 51 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 7969 | -0.031 | -0.2502 | No |
| 52 | DSCR1 | DSCR1 Entrez, Source | Down syndrome critical region gene 1 | 7972 | -0.031 | -0.2486 | No |
| 53 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8212 | -0.035 | -0.2646 | No |
| 54 | RAB5A | RAB5A Entrez, Source | RAB5A, member RAS oncogene family | 8227 | -0.036 | -0.2636 | No |
| 55 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 8342 | -0.038 | -0.2700 | No |
| 56 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 8369 | -0.039 | -0.2698 | No |
| 57 | SHOX2 | SHOX2 Entrez, Source | short stature homeobox 2 | 8562 | -0.043 | -0.2818 | No |
| 58 | YTHDC1 | YTHDC1 Entrez, Source | YTH domain containing 1 | 8628 | -0.044 | -0.2842 | No |
| 59 | IFITM3 | IFITM3 Entrez, Source | interferon induced transmembrane protein 3 (1-8U) | 8954 | -0.051 | -0.3058 | No |
| 60 | CREM | CREM Entrez, Source | cAMP responsive element modulator | 8985 | -0.051 | -0.3051 | No |
| 61 | DNAJB6 | DNAJB6 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 6 | 9020 | -0.052 | -0.3047 | No |
| 62 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 9220 | -0.056 | -0.3164 | No |
| 63 | ARPP-19 | ARPP-19 Entrez, Source | - | 9233 | -0.057 | -0.3141 | No |
| 64 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 9336 | -0.059 | -0.3184 | No |
| 65 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 9447 | -0.062 | -0.3231 | No |
| 66 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 9461 | -0.062 | -0.3205 | No |
| 67 | STX3 | STX3 Entrez, Source | syntaxin 3 | 9898 | -0.074 | -0.3492 | No |
| 68 | MKLN1 | MKLN1 Entrez, Source | muskelin 1, intracellular mediator containing kelch motifs | 9943 | -0.075 | -0.3482 | No |
| 69 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 9987 | -0.076 | -0.3471 | No |
| 70 | COPS2 | COPS2 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 10059 | -0.078 | -0.3479 | No |
| 71 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 10093 | -0.079 | -0.3458 | No |
| 72 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 10241 | -0.083 | -0.3522 | No |
| 73 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 10287 | -0.084 | -0.3507 | No |
| 74 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 10356 | -0.086 | -0.3509 | No |
| 75 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3539 | No |
| 76 | TIMM17A | TIMM17A Entrez, Source | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 10517 | -0.091 | -0.3525 | No |
| 77 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 10530 | -0.091 | -0.3481 | No |
| 78 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 10565 | -0.092 | -0.3453 | No |
| 79 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 10574 | -0.093 | -0.3406 | No |
| 80 | OGFR | OGFR Entrez, Source | opioid growth factor receptor | 10604 | -0.094 | -0.3374 | No |
| 81 | CETN3 | CETN3 Entrez, Source | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 10804 | -0.101 | -0.3466 | No |
| 82 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 10840 | -0.103 | -0.3433 | No |
| 83 | ADM | ADM Entrez, Source | adrenomedullin | 11063 | -0.110 | -0.3537 | No |
| 84 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | -0.3558 | Yes |
| 85 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 11205 | -0.116 | -0.3508 | Yes |
| 86 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.3444 | Yes |
| 87 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 11241 | -0.118 | -0.3399 | Yes |
| 88 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11293 | -0.120 | -0.3368 | Yes |
| 89 | FHL2 | FHL2 Entrez, Source | four and a half LIM domains 2 | 11359 | -0.123 | -0.3346 | Yes |
| 90 | UBE2V2 | UBE2V2 Entrez, Source | ubiquitin-conjugating enzyme E2 variant 2 | 11529 | -0.130 | -0.3398 | Yes |
| 91 | RAB21 | RAB21 Entrez, Source | RAB21, member RAS oncogene family | 11687 | -0.137 | -0.3437 | Yes |
| 92 | THUMPD1 | THUMPD1 Entrez, Source | THUMP domain containing 1 | 11754 | -0.141 | -0.3406 | Yes |
| 93 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 11943 | -0.153 | -0.3459 | Yes |
| 94 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 11948 | -0.154 | -0.3373 | Yes |
| 95 | NUPL1 | NUPL1 Entrez, Source | nucleoporin like 1 | 12051 | -0.161 | -0.3357 | Yes |
| 96 | RBM13 | RBM13 Entrez, Source | RNA binding motif protein 13 | 12381 | -0.186 | -0.3498 | Yes |
| 97 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 12410 | -0.189 | -0.3410 | Yes |
| 98 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 12529 | -0.202 | -0.3383 | Yes |
| 99 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 12536 | -0.203 | -0.3270 | Yes |
| 100 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 12556 | -0.205 | -0.3165 | Yes |
| 101 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 12585 | -0.209 | -0.3066 | Yes |
| 102 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 12656 | -0.218 | -0.2992 | Yes |
| 103 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 12678 | -0.221 | -0.2880 | Yes |
| 104 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 12680 | -0.221 | -0.2753 | Yes |
| 105 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 12750 | -0.233 | -0.2670 | Yes |
| 106 | EIF2B5 | EIF2B5 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa | 12772 | -0.237 | -0.2549 | Yes |
| 107 | SMAD5 | SMAD5 Entrez, Source | SMAD, mothers against DPP homolog 5 (Drosophila) | 12778 | -0.238 | -0.2415 | Yes |
| 108 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | -0.2337 | Yes |
| 109 | PRKAA1 | PRKAA1 Entrez, Source | protein kinase, AMP-activated, alpha 1 catalytic subunit | 13019 | -0.298 | -0.2273 | Yes |
| 110 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13034 | -0.303 | -0.2108 | Yes |
| 111 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 13047 | -0.306 | -0.1940 | Yes |
| 112 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 13115 | -0.335 | -0.1797 | Yes |
| 113 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 13119 | -0.337 | -0.1604 | Yes |
| 114 | HIST2H2AA3 | HIST2H2AA3 Entrez, Source | histone cluster 2, H2aa3 | 13238 | -0.448 | -0.1434 | Yes |
| 115 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13274 | -0.526 | -0.1156 | Yes |
| 116 | OTUD4 | OTUD4 Entrez, Source | OTU domain containing 4 | 13292 | -0.569 | -0.0840 | Yes |
| 117 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 13294 | -0.577 | -0.0506 | Yes |
| 118 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 13331 | -0.937 | 0.0008 | Yes |
