Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | RESPONSE_TO_WOUNDING |
| Enrichment Score (ES) | 0.5186307 |
| Normalized Enrichment Score (NES) | 1.9171999 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010625376 |
| FWER p-Value | 0.449 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 3 | 1.622 | 0.0703 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 25 | 0.995 | 0.1120 | Yes |
| 3 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 27 | 0.963 | 0.1538 | Yes |
| 4 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.1917 | Yes |
| 5 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 103 | 0.659 | 0.2154 | Yes |
| 6 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 114 | 0.625 | 0.2418 | Yes |
| 7 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 159 | 0.550 | 0.2624 | Yes |
| 8 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 186 | 0.510 | 0.2826 | Yes |
| 9 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.3008 | Yes |
| 10 | CRP | CRP Entrez, Source | C-reactive protein, pentraxin-related | 272 | 0.422 | 0.3151 | Yes |
| 11 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 279 | 0.415 | 0.3327 | Yes |
| 12 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 321 | 0.383 | 0.3462 | Yes |
| 13 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 364 | 0.357 | 0.3585 | Yes |
| 14 | F9 | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 369 | 0.352 | 0.3735 | Yes |
| 15 | KLRG1 | KLRG1 Entrez, Source | killer cell lectin-like receptor subfamily G, member 1 | 457 | 0.304 | 0.3802 | Yes |
| 16 | IRAK2 | IRAK2 Entrez, Source | interleukin-1 receptor-associated kinase 2 | 464 | 0.300 | 0.3927 | Yes |
| 17 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 474 | 0.294 | 0.4049 | Yes |
| 18 | CD40 | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 539 | 0.273 | 0.4119 | Yes |
| 19 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 563 | 0.266 | 0.4217 | Yes |
| 20 | TPST1 | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 617 | 0.253 | 0.4287 | Yes |
| 21 | LBP | LBP Entrez, Source | lipopolysaccharide binding protein | 636 | 0.247 | 0.4381 | Yes |
| 22 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 689 | 0.237 | 0.4445 | Yes |
| 23 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 718 | 0.232 | 0.4524 | Yes |
| 24 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 725 | 0.231 | 0.4620 | Yes |
| 25 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 740 | 0.229 | 0.4709 | Yes |
| 26 | DCBLD2 | DCBLD2 Entrez, Source | discoidin, CUB and LCCL domain containing 2 | 742 | 0.228 | 0.4807 | Yes |
| 27 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 796 | 0.215 | 0.4861 | Yes |
| 28 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 818 | 0.210 | 0.4936 | Yes |
| 29 | THBD | THBD Entrez, Source | thrombomodulin | 877 | 0.198 | 0.4978 | Yes |
| 30 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 901 | 0.195 | 0.5046 | Yes |
| 31 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.5119 | Yes |
| 32 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1043 | 0.177 | 0.5101 | Yes |
| 33 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 1052 | 0.177 | 0.5172 | Yes |
| 34 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 1240 | 0.157 | 0.5098 | Yes |
| 35 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 1345 | 0.147 | 0.5083 | Yes |
| 36 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 1394 | 0.143 | 0.5109 | Yes |
| 37 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1486 | 0.136 | 0.5100 | Yes |
| 38 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 1508 | 0.134 | 0.5142 | Yes |
| 39 | IL8RA | IL8RA Entrez, Source | interleukin 8 receptor, alpha | 1527 | 0.133 | 0.5186 | Yes |
| 40 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 1722 | 0.122 | 0.5092 | No |
| 41 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 1901 | 0.112 | 0.5006 | No |
| 42 | EREG | EREG Entrez, Source | epiregulin | 1968 | 0.109 | 0.5004 | No |
| 43 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 1973 | 0.109 | 0.5048 | No |
| 44 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 2056 | 0.105 | 0.5032 | No |
| 45 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 2076 | 0.105 | 0.5063 | No |
| 46 | HDAC7A | HDAC7A Entrez, Source | histone deacetylase 7A | 2133 | 0.102 | 0.5065 | No |
| 47 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 2217 | 0.099 | 0.5045 | No |
| 48 | VWF | VWF Entrez, Source | von Willebrand factor | 2400 | 0.092 | 0.4947 | No |
| 49 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 2467 | 0.089 | 0.4936 | No |
| 50 | ADORA3 | ADORA3 Entrez, Source | adenosine A3 receptor | 2617 | 0.083 | 0.4859 | No |
| 51 | BLNK | BLNK Entrez, Source | B-cell linker | 2743 | 0.079 | 0.4799 | No |
| 52 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 2907 | 0.074 | 0.4708 | No |
| 53 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 3188 | 0.066 | 0.4524 | No |
| 54 | CCL11 | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 3370 | 0.061 | 0.4414 | No |
| 55 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 3401 | 0.060 | 0.4417 | No |
| 56 | ACVRL1 | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 3520 | 0.057 | 0.4353 | No |
| 57 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 3552 | 0.056 | 0.4354 | No |
| 58 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 3686 | 0.053 | 0.4276 | No |
| 59 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 3767 | 0.051 | 0.4237 | No |
| 60 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 3800 | 0.050 | 0.4235 | No |
| 61 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 3936 | 0.046 | 0.4153 | No |
| 62 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 3950 | 0.046 | 0.4163 | No |
| 63 | F2RL2 | F2RL2 Entrez, Source | coagulation factor II (thrombin) receptor-like 2 | 4002 | 0.045 | 0.4144 | No |
| 64 | F11R | F11R Entrez, Source | F11 receptor | 4372 | 0.036 | 0.3880 | No |
| 65 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 4583 | 0.032 | 0.3735 | No |
| 66 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 4778 | 0.028 | 0.3601 | No |
| 67 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 4875 | 0.027 | 0.3540 | No |
| 68 | TACR1 | TACR1 Entrez, Source | tachykinin receptor 1 | 5085 | 0.023 | 0.3391 | No |
| 69 | MEFV | MEFV Entrez, Source | Mediterranean fever | 5464 | 0.016 | 0.3112 | No |
| 70 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 5475 | 0.015 | 0.3111 | No |
| 71 | CCR4 | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 5494 | 0.015 | 0.3104 | No |
| 72 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 5594 | 0.013 | 0.3035 | No |
| 73 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 5606 | 0.013 | 0.3032 | No |
| 74 | SIGIRR | SIGIRR Entrez, Source | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 5629 | 0.012 | 0.3020 | No |
| 75 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 5694 | 0.011 | 0.2977 | No |
| 76 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 5892 | 0.007 | 0.2831 | No |
| 77 | CX3CR1 | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 5914 | 0.007 | 0.2818 | No |
| 78 | CD97 | CD97 Entrez, Source | CD97 molecule | 5995 | 0.005 | 0.2760 | No |
| 79 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 6062 | 0.004 | 0.2711 | No |
| 80 | IL5 | IL5 Entrez, Source | interleukin 5 (colony-stimulating factor, eosinophil) | 6076 | 0.004 | 0.2703 | No |
| 81 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 6231 | 0.001 | 0.2587 | No |
| 82 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 6379 | -0.001 | 0.2476 | No |
| 83 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 6393 | -0.002 | 0.2467 | No |
| 84 | IL13 | IL13 Entrez, Source | interleukin 13 | 6740 | -0.008 | 0.2209 | No |
| 85 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7093 | -0.014 | 0.1948 | No |
| 86 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 7142 | -0.015 | 0.1918 | No |
| 87 | F10 | F10 Entrez, Source | coagulation factor X | 7144 | -0.015 | 0.1924 | No |
| 88 | CD40LG | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 7233 | -0.017 | 0.1864 | No |
| 89 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 7442 | -0.021 | 0.1716 | No |
| 90 | F8 | F8 Entrez, Source | coagulation factor VIII, procoagulant component (hemophilia A) | 7586 | -0.023 | 0.1618 | No |
| 91 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 7625 | -0.024 | 0.1599 | No |
| 92 | PTAFR | PTAFR Entrez, Source | platelet-activating factor receptor | 7629 | -0.024 | 0.1608 | No |
| 93 | LMAN1 | LMAN1 Entrez, Source | lectin, mannose-binding, 1 | 7769 | -0.027 | 0.1514 | No |
| 94 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 8298 | -0.037 | 0.1131 | No |
| 95 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 8306 | -0.037 | 0.1142 | No |
| 96 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 8318 | -0.038 | 0.1150 | No |
| 97 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 8400 | -0.039 | 0.1106 | No |
| 98 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 8582 | -0.043 | 0.0987 | No |
| 99 | HRH1 | HRH1 Entrez, Source | histamine receptor H1 | 8600 | -0.043 | 0.0993 | No |
| 100 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 8654 | -0.044 | 0.0973 | No |
| 101 | CCR3 | CCR3 Entrez, Source | chemokine (C-C motif) receptor 3 | 8807 | -0.048 | 0.0878 | No |
| 102 | GNA12 | GNA12 Entrez, Source | guanine nucleotide binding protein (G protein) alpha 12 | 8878 | -0.049 | 0.0847 | No |
| 103 | ADORA2A | ADORA2A Entrez, Source | adenosine A2a receptor | 8894 | -0.050 | 0.0857 | No |
| 104 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9101 | -0.054 | 0.0725 | No |
| 105 | PLG | PLG Entrez, Source | plasminogen | 9113 | -0.054 | 0.0740 | No |
| 106 | CYBB | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 9683 | -0.067 | 0.0339 | No |
| 107 | PLA2G2D | PLA2G2D Entrez, Source | phospholipase A2, group IID | 9730 | -0.069 | 0.0334 | No |
| 108 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 9852 | -0.072 | 0.0274 | No |
| 109 | F2RL3 | F2RL3 Entrez, Source | coagulation factor II (thrombin) receptor-like 3 | 10199 | -0.082 | 0.0047 | No |
| 110 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 10277 | -0.084 | 0.0025 | No |
| 111 | C2 | C2 Entrez, Source | complement component 2 | 10542 | -0.091 | -0.0135 | No |
| 112 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 10551 | -0.092 | -0.0101 | No |
| 113 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 10565 | -0.092 | -0.0071 | No |
| 114 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 10574 | -0.093 | -0.0036 | No |
| 115 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 10650 | -0.095 | -0.0052 | No |
| 116 | ADM | ADM Entrez, Source | adrenomedullin | 11063 | -0.110 | -0.0316 | No |
| 117 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 11087 | -0.111 | -0.0285 | No |
| 118 | CFHR1 | CFHR1 Entrez, Source | complement factor H-related 1 | 11475 | -0.128 | -0.0522 | No |
| 119 | APCS | APCS Entrez, Source | amyloid P component, serum | 11626 | -0.135 | -0.0577 | No |
| 120 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 11945 | -0.153 | -0.0751 | No |
| 121 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 11957 | -0.154 | -0.0692 | No |
| 122 | ABCF1 | ABCF1 Entrez, Source | ATP-binding cassette, sub-family F (GCN20), member 1 | 11995 | -0.157 | -0.0652 | No |
| 123 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 12176 | -0.170 | -0.0715 | No |
| 124 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 12379 | -0.186 | -0.0787 | No |
| 125 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 12401 | -0.188 | -0.0721 | No |
| 126 | C4BPB | C4BPB Entrez, Source | complement component 4 binding protein, beta | 12817 | -0.245 | -0.0928 | No |
| 127 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 12851 | -0.254 | -0.0843 | No |
| 128 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12951 | -0.277 | -0.0797 | No |
| 129 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 13304 | -0.615 | -0.0796 | No |
| 130 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13322 | -0.789 | -0.0466 | No |
| 131 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 13337 | -1.105 | 0.0004 | No |
