Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | RNA_BINDING |
| Enrichment Score (ES) | -0.54713434 |
| Normalized Enrichment Score (NES) | -2.1885777 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.939983E-4 |
| FWER p-Value | 0.0010 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 237 | 0.454 | 0.0107 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 746 | 0.228 | -0.0134 | No |
| 3 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 1051 | 0.177 | -0.0253 | No |
| 4 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | -0.0154 | No |
| 5 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 1501 | 0.135 | -0.0398 | No |
| 6 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1511 | 0.134 | -0.0320 | No |
| 7 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 2449 | 0.090 | -0.0973 | No |
| 8 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 2480 | 0.089 | -0.0940 | No |
| 9 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 2930 | 0.073 | -0.1234 | No |
| 10 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3462 | 0.059 | -0.1599 | No |
| 11 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 3522 | 0.057 | -0.1608 | No |
| 12 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 3664 | 0.053 | -0.1681 | No |
| 13 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 3826 | 0.050 | -0.1772 | No |
| 14 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 4049 | 0.043 | -0.1913 | No |
| 15 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 4464 | 0.035 | -0.2204 | No |
| 16 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 4845 | 0.027 | -0.2475 | No |
| 17 | RNASEL | RNASEL Entrez, Source | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | 5458 | 0.016 | -0.2929 | No |
| 18 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 5776 | 0.009 | -0.3163 | No |
| 19 | MRPS7 | MRPS7 Entrez, Source | mitochondrial ribosomal protein S7 | 5787 | 0.009 | -0.3165 | No |
| 20 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 5924 | 0.007 | -0.3263 | No |
| 21 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 6092 | 0.003 | -0.3388 | No |
| 22 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 6115 | 0.003 | -0.3403 | No |
| 23 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 6498 | -0.004 | -0.3690 | No |
| 24 | MRPL23 | MRPL23 Entrez, Source | mitochondrial ribosomal protein L23 | 6562 | -0.005 | -0.3734 | No |
| 25 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.3831 | No |
| 26 | RTCD1 | RTCD1 Entrez, Source | RNA terminal phosphate cyclase domain 1 | 6731 | -0.008 | -0.3851 | No |
| 27 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 6776 | -0.009 | -0.3879 | No |
| 28 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 6962 | -0.012 | -0.4012 | No |
| 29 | ADARB2 | ADARB2 Entrez, Source | adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) | 7111 | -0.014 | -0.4115 | No |
| 30 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 7346 | -0.019 | -0.4281 | No |
| 31 | RPS29 | RPS29 Entrez, Source | ribosomal protein S29 | 7396 | -0.020 | -0.4306 | No |
| 32 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 7399 | -0.020 | -0.4295 | No |
| 33 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 7694 | -0.025 | -0.4501 | No |
| 34 | RPLP1 | RPLP1 Entrez, Source | ribosomal protein, large, P1 | 7767 | -0.027 | -0.4539 | No |
| 35 | RPL19 | RPL19 Entrez, Source | ribosomal protein L19 | 8070 | -0.033 | -0.4747 | No |
| 36 | RPL26 | RPL26 Entrez, Source | ribosomal protein L26 | 8186 | -0.035 | -0.4812 | No |
| 37 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 8393 | -0.039 | -0.4944 | No |
| 38 | RPS6 | RPS6 Entrez, Source | ribosomal protein S6 | 8450 | -0.040 | -0.4961 | No |
| 39 | RPL31 | RPL31 Entrez, Source | ribosomal protein L31 | 8497 | -0.041 | -0.4969 | No |
| 40 | STAU2 | STAU2 Entrez, Source | staufen, RNA binding protein, homolog 2 (Drosophila) | 8584 | -0.043 | -0.5007 | No |
| 41 | SLU7 | SLU7 Entrez, Source | - | 8593 | -0.043 | -0.4986 | No |
| 42 | RPS21 | RPS21 Entrez, Source | ribosomal protein S21 | 8696 | -0.045 | -0.5035 | No |
| 43 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 8874 | -0.049 | -0.5138 | No |
| 44 | RPS17 | RPS17 Entrez, Source | ribosomal protein S17 | 9049 | -0.053 | -0.5236 | No |
| 45 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 9255 | -0.057 | -0.5356 | No |
| 46 | RPL9 | RPL9 Entrez, Source | ribosomal protein L9 | 9388 | -0.060 | -0.5418 | No |
| 47 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9460 | -0.062 | -0.5432 | Yes |
| 48 | RPS3A | RPS3A Entrez, Source | ribosomal protein S3A | 9486 | -0.063 | -0.5412 | Yes |
| 49 | SUPV3L1 | SUPV3L1 Entrez, Source | suppressor of var1, 3-like 1 (S. cerevisiae) | 9489 | -0.063 | -0.5374 | Yes |
| 50 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9506 | -0.063 | -0.5346 | Yes |
| 51 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 9528 | -0.063 | -0.5322 | Yes |
| 52 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 9531 | -0.064 | -0.5284 | Yes |
| 53 | HNRPK | HNRPK Entrez, Source | heterogeneous nuclear ribonucleoprotein K | 9627 | -0.066 | -0.5314 | Yes |
| 54 | RPS8 | RPS8 Entrez, Source | ribosomal protein S8 | 9640 | -0.066 | -0.5281 | Yes |
| 55 | RPS24 | RPS24 Entrez, Source | ribosomal protein S24 | 9729 | -0.069 | -0.5305 | Yes |
| 56 | RPS13 | RPS13 Entrez, Source | ribosomal protein S13 | 9736 | -0.069 | -0.5266 | Yes |
| 57 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 9763 | -0.070 | -0.5241 | Yes |
| 58 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 9854 | -0.073 | -0.5264 | Yes |
| 59 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 9858 | -0.073 | -0.5220 | Yes |
| 60 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 9980 | -0.076 | -0.5264 | Yes |
| 61 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10089 | -0.079 | -0.5296 | Yes |
| 62 | HNRPH1 | HNRPH1 Entrez, Source | heterogeneous nuclear ribonucleoprotein H1 (H) | 10163 | -0.081 | -0.5301 | Yes |
| 63 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 10178 | -0.081 | -0.5260 | Yes |
| 64 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 10207 | -0.082 | -0.5230 | Yes |
| 65 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 10242 | -0.083 | -0.5204 | Yes |
| 66 | RPL13 | RPL13 Entrez, Source | ribosomal protein L13 | 10259 | -0.083 | -0.5163 | Yes |
| 67 | RPL21 | RPL21 Entrez, Source | ribosomal protein L21 | 10261 | -0.083 | -0.5111 | Yes |
| 68 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 10262 | -0.083 | -0.5059 | Yes |
| 69 | TEP1 | TEP1 Entrez, Source | telomerase-associated protein 1 | 10265 | -0.083 | -0.5008 | Yes |
| 70 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 10277 | -0.084 | -0.4963 | Yes |
| 71 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 10288 | -0.084 | -0.4918 | Yes |
| 72 | RPS26 | RPS26 Entrez, Source | ribosomal protein S26 | 10314 | -0.085 | -0.4883 | Yes |
| 73 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 10325 | -0.085 | -0.4837 | Yes |
| 74 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10349 | -0.086 | -0.4801 | Yes |
| 75 | RPS15A | RPS15A Entrez, Source | ribosomal protein S15a | 10391 | -0.087 | -0.4777 | Yes |
| 76 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 10402 | -0.087 | -0.4729 | Yes |
| 77 | RPS23 | RPS23 Entrez, Source | ribosomal protein S23 | 10436 | -0.088 | -0.4699 | Yes |
| 78 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 10613 | -0.094 | -0.4773 | Yes |
| 79 | RPS12 | RPS12 Entrez, Source | ribosomal protein S12 | 10633 | -0.095 | -0.4727 | Yes |
| 80 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 10646 | -0.095 | -0.4676 | Yes |
| 81 | RPL24 | RPL24 Entrez, Source | ribosomal protein L24 | 10666 | -0.096 | -0.4630 | Yes |
| 82 | RPL7 | RPL7 Entrez, Source | ribosomal protein L7 | 10672 | -0.096 | -0.4573 | Yes |
| 83 | RPL30 | RPL30 Entrez, Source | ribosomal protein L30 | 10673 | -0.096 | -0.4513 | Yes |
| 84 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 10766 | -0.100 | -0.4520 | Yes |
| 85 | RPS5 | RPS5 Entrez, Source | ribosomal protein S5 | 10811 | -0.101 | -0.4489 | Yes |
| 86 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 10840 | -0.103 | -0.4446 | Yes |
| 87 | RPS10 | RPS10 Entrez, Source | ribosomal protein S10 | 10873 | -0.104 | -0.4404 | Yes |
| 88 | RNASEH1 | RNASEH1 Entrez, Source | ribonuclease H1 | 10932 | -0.106 | -0.4381 | Yes |
| 89 | CIRBP | CIRBP Entrez, Source | cold inducible RNA binding protein | 10982 | -0.108 | -0.4351 | Yes |
| 90 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11050 | -0.110 | -0.4332 | Yes |
| 91 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 11080 | -0.111 | -0.4284 | Yes |
| 92 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 11085 | -0.111 | -0.4217 | Yes |
| 93 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 11168 | -0.115 | -0.4206 | Yes |
| 94 | RPS27 | RPS27 Entrez, Source | ribosomal protein S27 (metallopanstimulin 1) | 11176 | -0.115 | -0.4139 | Yes |
| 95 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.4090 | Yes |
| 96 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11293 | -0.120 | -0.4077 | Yes |
| 97 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 11310 | -0.121 | -0.4013 | Yes |
| 98 | RPL22 | RPL22 Entrez, Source | ribosomal protein L22 | 11388 | -0.124 | -0.3993 | Yes |
| 99 | SERBP1 | SERBP1 Entrez, Source | SERPINE1 mRNA binding protein 1 | 11399 | -0.125 | -0.3922 | Yes |
| 100 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 11406 | -0.125 | -0.3848 | Yes |
| 101 | RPS3 | RPS3 Entrez, Source | ribosomal protein S3 | 11507 | -0.129 | -0.3842 | Yes |
| 102 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11541 | -0.131 | -0.3784 | Yes |
| 103 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 11683 | -0.137 | -0.3804 | Yes |
| 104 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 11760 | -0.142 | -0.3773 | Yes |
| 105 | RPL14 | RPL14 Entrez, Source | ribosomal protein L14 | 11799 | -0.144 | -0.3710 | Yes |
| 106 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 11806 | -0.145 | -0.3624 | Yes |
| 107 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11965 | -0.155 | -0.3646 | Yes |
| 108 | ROD1 | ROD1 Entrez, Source | ROD1 regulator of differentiation 1 (S. pombe) | 11981 | -0.156 | -0.3559 | Yes |
| 109 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 11984 | -0.156 | -0.3462 | Yes |
| 110 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11985 | -0.156 | -0.3363 | Yes |
| 111 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 12068 | -0.162 | -0.3323 | Yes |
| 112 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12145 | -0.168 | -0.3275 | Yes |
| 113 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 12147 | -0.168 | -0.3170 | Yes |
| 114 | ETF1 | ETF1 Entrez, Source | eukaryotic translation termination factor 1 | 12148 | -0.168 | -0.3064 | Yes |
| 115 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12198 | -0.171 | -0.2993 | Yes |
| 116 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12234 | -0.174 | -0.2910 | Yes |
| 117 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.2817 | Yes |
| 118 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12304 | -0.180 | -0.2737 | Yes |
| 119 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.2644 | Yes |
| 120 | RPS25 | RPS25 Entrez, Source | ribosomal protein S25 | 12343 | -0.183 | -0.2535 | Yes |
| 121 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 12393 | -0.187 | -0.2454 | Yes |
| 122 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 12401 | -0.188 | -0.2341 | Yes |
| 123 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12402 | -0.188 | -0.2222 | Yes |
| 124 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 12413 | -0.189 | -0.2110 | Yes |
| 125 | FBL | FBL Entrez, Source | fibrillarin | 12456 | -0.194 | -0.2020 | Yes |
| 126 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12466 | -0.195 | -0.1904 | Yes |
| 127 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 12473 | -0.196 | -0.1785 | Yes |
| 128 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12534 | -0.203 | -0.1702 | Yes |
| 129 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12614 | -0.213 | -0.1628 | Yes |
| 130 | APOBEC1 | APOBEC1 Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 12633 | -0.215 | -0.1506 | Yes |
| 131 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12665 | -0.219 | -0.1391 | Yes |
| 132 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.1303 | Yes |
| 133 | RPL39 | RPL39 Entrez, Source | ribosomal protein L39 | 12758 | -0.234 | -0.1166 | Yes |
| 134 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.1034 | Yes |
| 135 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.0908 | Yes |
| 136 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.0772 | Yes |
| 137 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 12861 | -0.256 | -0.0613 | Yes |
| 138 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 12873 | -0.260 | -0.0458 | Yes |
| 139 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12895 | -0.266 | -0.0306 | Yes |
| 140 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.0166 | Yes |
| 141 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13034 | -0.303 | -0.0046 | Yes |
| 142 | APTX | APTX Entrez, Source | aprataxin | 13232 | -0.441 | 0.0083 | Yes |
