Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | RNA_PROCESSING |
| Enrichment Score (ES) | -0.53881043 |
| Normalized Enrichment Score (NES) | -1.9436635 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.01628122 |
| FWER p-Value | 0.248 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 237 | 0.454 | 0.0326 | No |
| 2 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 746 | 0.228 | 0.0196 | No |
| 3 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | 0.0149 | No |
| 4 | AGGF1 | AGGF1 Entrez, Source | angiogenic factor with G patch and FHA domains 1 | 1846 | 0.115 | -0.0311 | No |
| 5 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 3522 | 0.057 | -0.1510 | No |
| 6 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 3623 | 0.054 | -0.1525 | No |
| 7 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 3664 | 0.053 | -0.1496 | No |
| 8 | FARS2 | FARS2 Entrez, Source | phenylalanine-tRNA synthetase 2 (mitochondrial) | 3826 | 0.050 | -0.1562 | No |
| 9 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 4049 | 0.043 | -0.1681 | No |
| 10 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 4346 | 0.037 | -0.1863 | No |
| 11 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 4464 | 0.035 | -0.1913 | No |
| 12 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 5776 | 0.009 | -0.2891 | No |
| 13 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 6401 | -0.002 | -0.3359 | No |
| 14 | INTS6 | INTS6 Entrez, Source | integrator complex subunit 6 | 6560 | -0.005 | -0.3473 | No |
| 15 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.3530 | No |
| 16 | TRNT1 | TRNT1 Entrez, Source | tRNA nucleotidyl transferase, CCA-adding, 1 | 6776 | -0.009 | -0.3617 | No |
| 17 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 6946 | -0.011 | -0.3732 | No |
| 18 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 7006 | -0.012 | -0.3763 | No |
| 19 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 7029 | -0.013 | -0.3765 | No |
| 20 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 7645 | -0.024 | -0.4201 | No |
| 21 | SLU7 | SLU7 Entrez, Source | - | 8593 | -0.043 | -0.4867 | No |
| 22 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 9013 | -0.052 | -0.5125 | No |
| 23 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9167 | -0.055 | -0.5179 | No |
| 24 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 9255 | -0.057 | -0.5181 | No |
| 25 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.5133 | No |
| 26 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 9303 | -0.058 | -0.5087 | No |
| 27 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 9480 | -0.062 | -0.5151 | No |
| 28 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9796 | -0.071 | -0.5310 | Yes |
| 29 | RPS14 | RPS14 Entrez, Source | ribosomal protein S14 | 9858 | -0.073 | -0.5275 | Yes |
| 30 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 9980 | -0.076 | -0.5282 | Yes |
| 31 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10089 | -0.079 | -0.5276 | Yes |
| 32 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 10207 | -0.082 | -0.5273 | Yes |
| 33 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 10229 | -0.082 | -0.5197 | Yes |
| 34 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10252 | -0.083 | -0.5122 | Yes |
| 35 | POP4 | POP4 Entrez, Source | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | 10262 | -0.083 | -0.5036 | Yes |
| 36 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 10277 | -0.084 | -0.4954 | Yes |
| 37 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 10325 | -0.085 | -0.4894 | Yes |
| 38 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10349 | -0.086 | -0.4816 | Yes |
| 39 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 10840 | -0.103 | -0.5072 | Yes |
| 40 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 10842 | -0.103 | -0.4959 | Yes |
| 41 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 10877 | -0.104 | -0.4869 | Yes |
| 42 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 11009 | -0.109 | -0.4847 | Yes |
| 43 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11050 | -0.110 | -0.4755 | Yes |
| 44 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11175 | -0.115 | -0.4721 | Yes |
| 45 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.4617 | Yes |
| 46 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11293 | -0.120 | -0.4545 | Yes |
| 47 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 11519 | -0.130 | -0.4571 | Yes |
| 48 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11541 | -0.131 | -0.4441 | Yes |
| 49 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 11683 | -0.137 | -0.4395 | Yes |
| 50 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 11965 | -0.155 | -0.4435 | Yes |
| 51 | SSB | SSB Entrez, Source | Sjogren syndrome antigen B (autoantigen La) | 11984 | -0.156 | -0.4275 | Yes |
| 52 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11985 | -0.156 | -0.4102 | Yes |
| 53 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.3964 | Yes |
| 54 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12145 | -0.168 | -0.3857 | Yes |
| 55 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12161 | -0.169 | -0.3681 | Yes |
| 56 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 12234 | -0.174 | -0.3542 | Yes |
| 57 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12304 | -0.180 | -0.3394 | Yes |
| 58 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.3214 | Yes |
| 59 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12402 | -0.188 | -0.3055 | Yes |
| 60 | DUSP11 | DUSP11 Entrez, Source | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 12413 | -0.189 | -0.2852 | Yes |
| 61 | FBL | FBL Entrez, Source | fibrillarin | 12456 | -0.194 | -0.2669 | Yes |
| 62 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12466 | -0.195 | -0.2459 | Yes |
| 63 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12534 | -0.203 | -0.2285 | Yes |
| 64 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12614 | -0.213 | -0.2108 | Yes |
| 65 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.1876 | Yes |
| 66 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12665 | -0.219 | -0.1664 | Yes |
| 67 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12732 | -0.229 | -0.1459 | Yes |
| 68 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.1209 | Yes |
| 69 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.0974 | Yes |
| 70 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12895 | -0.266 | -0.0763 | Yes |
| 71 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 12901 | -0.267 | -0.0470 | Yes |
| 72 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12968 | -0.282 | -0.0207 | Yes |
| 73 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | 0.0087 | Yes |
