Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | RNA_SPLICING |
| Enrichment Score (ES) | -0.5041915 |
| Normalized Enrichment Score (NES) | -1.6006142 |
| Nominal p-value | 0.00896861 |
| FDR q-value | 0.16642919 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 237 | 0.454 | 0.0724 | No |
| 2 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | 0.0448 | No |
| 3 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 3623 | 0.054 | -0.1365 | No |
| 4 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 3664 | 0.053 | -0.1290 | No |
| 5 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 4049 | 0.043 | -0.1492 | No |
| 6 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 4346 | 0.037 | -0.1642 | No |
| 7 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.3357 | No |
| 8 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 7006 | -0.012 | -0.3603 | No |
| 9 | SLU7 | SLU7 Entrez, Source | - | 8593 | -0.043 | -0.4709 | No |
| 10 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 9013 | -0.052 | -0.4920 | No |
| 11 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9167 | -0.055 | -0.4926 | Yes |
| 12 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.4893 | Yes |
| 13 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 9303 | -0.058 | -0.4797 | Yes |
| 14 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 9480 | -0.062 | -0.4805 | Yes |
| 15 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 9796 | -0.071 | -0.4902 | Yes |
| 16 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 9980 | -0.076 | -0.4888 | Yes |
| 17 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10089 | -0.079 | -0.4813 | Yes |
| 18 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 10229 | -0.082 | -0.4754 | Yes |
| 19 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10252 | -0.083 | -0.4605 | Yes |
| 20 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 10325 | -0.085 | -0.4490 | Yes |
| 21 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 10840 | -0.103 | -0.4673 | Yes |
| 22 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 10842 | -0.103 | -0.4470 | Yes |
| 23 | PPAN | PPAN Entrez, Source | peter pan homolog (Drosophila) | 10877 | -0.104 | -0.4289 | Yes |
| 24 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 11009 | -0.109 | -0.4172 | Yes |
| 25 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11175 | -0.115 | -0.4067 | Yes |
| 26 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.3861 | Yes |
| 27 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 11519 | -0.130 | -0.3835 | Yes |
| 28 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11985 | -0.156 | -0.3874 | Yes |
| 29 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.3596 | Yes |
| 30 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12145 | -0.168 | -0.3342 | Yes |
| 31 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12161 | -0.169 | -0.3018 | Yes |
| 32 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12304 | -0.180 | -0.2768 | Yes |
| 33 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.2428 | Yes |
| 34 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12402 | -0.188 | -0.2105 | Yes |
| 35 | HNRPF | HNRPF Entrez, Source | heterogeneous nuclear ribonucleoprotein F | 12466 | -0.195 | -0.1766 | Yes |
| 36 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12534 | -0.203 | -0.1414 | Yes |
| 37 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12732 | -0.229 | -0.1106 | Yes |
| 38 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.0671 | Yes |
| 39 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 12901 | -0.267 | -0.0229 | Yes |
| 40 | ASCC3L1 | ASCC3L1 Entrez, Source | activating signal cointegrator 1 complex subunit 3-like 1 | 12968 | -0.282 | 0.0281 | Yes |
