Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetROS_MOUSE_AORTA_DN
Enrichment Score (ES)0.5855918
Normalized Enrichment Score (NES)1.8900795
Nominal p-value0.0
FDR q-value0.014089726
FWER p-Value0.581
Table: GSEA Results Summary



Fig 1: Enrichment plot: ROS_MOUSE_AORTA_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CD9CD9
Entrez,  Source
CD9 molecule410.8710.0708Yes
2RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa500.8100.1389Yes
3S100A6S100A6
Entrez,  Source
S100 calcium binding protein A6550.7850.2052Yes
4LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1030.6590.2575Yes
5MGPMGP
Entrez,  Source
matrix Gla protein1080.6440.3118Yes
6IL1R2IL1R2
Entrez,  Source
interleukin 1 receptor, type II1400.5820.3589Yes
7ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A11850.5100.3988Yes
8BGNBGN
Entrez,  Source
biglycan2410.4500.4328Yes
9GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)2420.4490.4709Yes
10CYBACYBA
Entrez,  Source
cytochrome b-245, alpha polypeptide2640.4270.5056Yes
11ARG1ARG1
Entrez,  Source
arginase, liver3070.3970.5361Yes
12FXYD5FXYD5
Entrez,  Source
FXYD domain containing ion transport regulator 53560.3620.5632Yes
13ANXA3ANXA3
Entrez,  Source
annexin A34840.2910.5783Yes
14EMP3EMP3
Entrez,  Source
epithelial membrane protein 36620.2430.5856Yes
15PTGISPTGIS
Entrez,  Source
prostaglandin I2 (prostacyclin) synthase11070.1700.5666No
16CTSSCTSS
Entrez,  Source
cathepsin S12640.1540.5679No
17SYN1SYN1
Entrez,  Source
synapsin I14600.1380.5650No
18GNAI2GNAI2
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 215850.1290.5666No
19ARG2ARG2
Entrez,  Source
arginase, type II16060.1280.5759No
20ATF3ATF3
Entrez,  Source
activating transcription factor 320350.1060.5527No
21HDCHDC
Entrez,  Source
histidine decarboxylase21550.1010.5524No
22RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular25910.0840.5267No
23SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)30390.0700.4990No
24ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)31030.0680.5001No
25SFRP2SFRP2
Entrez,  Source
secreted frizzled-related protein 232470.0640.4947No
26ENAHENAH
Entrez,  Source
enabled homolog (Drosophila)35230.0570.4789No
27HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)37150.0520.4689No
28DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)41980.0400.4360No
29CPECPE
Entrez,  Source
carboxypeptidase E42220.0390.4376No
30SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 144690.0350.4220No
31CSRP1CSRP1
Entrez,  Source
cysteine and glycine-rich protein 145220.0330.4209No
32CAPZBCAPZB
Entrez,  Source
capping protein (actin filament) muscle Z-line, beta52250.0200.3697No
33CLUCLU
Entrez,  Source
clusterin54430.0160.3548No
34BTG3BTG3
Entrez,  Source
BTG family, member 355920.0130.3447No
35ACTBACTB
Entrez,  Source
actin, beta57880.0090.3308No
36TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)6293-0.0000.2929No
37IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 56450-0.0030.2814No
38ARL6IP2ARL6IP2
Entrez,  Source
ADP-ribosylation factor-like 6 interacting protein 26899-0.0100.2486No
39PMP22PMP22
Entrez,  Source
peripheral myelin protein 226967-0.0120.2445No
40LCP1LCP1
Entrez,  Source
lymphocyte cytosolic protein 1 (L-plastin)7308-0.0180.2205No
41ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)7315-0.0180.2215No
42MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle8278-0.0370.1523No
43S100A9S100A9
Entrez,  Source
S100 calcium binding protein A98582-0.0430.1331No
44PTPN23PTPN23
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 238963-0.0510.1088No
45IL1BIL1B
Entrez,  Source
interleukin 1, beta9721-0.0690.0577No
46MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)10293-0.0840.0219No
47RPL18RPL18
Entrez,  Source
ribosomal protein L1810646-0.0950.0035No
48RPS5RPS5
Entrez,  Source
ribosomal protein S510811-0.101-0.0003No
49RCN2RCN2
Entrez,  Source
reticulocalbin 2, EF-hand calcium binding domain11596-0.133-0.0480No
50EXOSC7EXOSC7
Entrez,  Source
exosome component 711683-0.137-0.0428No
51CD14CD14
Entrez,  Source
CD14 molecule12462-0.194-0.0849No
52BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 212874-0.260-0.0938No
53GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta12969-0.282-0.0769No
54PON1PON1
Entrez,  Source
paraoxonase 113224-0.431-0.0595No
55CD5LCD5L
Entrez,  Source
CD5 molecule-like13324-0.8050.0014No
Table: GSEA details [plain text format]



Fig 2: ROS_MOUSE_AORTA_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ROS_MOUSE_AORTA_DN: Random ES distribution   
Gene set null distribution of ES for ROS_MOUSE_AORTA_DN