Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | SERUM_FIBROBLAST_CORE_UP |
| Enrichment Score (ES) | -0.37278894 |
| Normalized Enrichment Score (NES) | -1.4476165 |
| Nominal p-value | 0.018518519 |
| FDR q-value | 0.2520914 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GPLD1 | GPLD1 Entrez, Source | glycosylphosphatidylinositol specific phospholipase D1 | 344 | 0.368 | 0.0032 | No |
| 2 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 355 | 0.363 | 0.0313 | No |
| 3 | TPRKB | TPRKB Entrez, Source | TP53RK binding protein | 392 | 0.341 | 0.0556 | No |
| 4 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 401 | 0.337 | 0.0818 | No |
| 5 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 574 | 0.263 | 0.0897 | No |
| 6 | DCBLD2 | DCBLD2 Entrez, Source | discoidin, CUB and LCCL domain containing 2 | 742 | 0.228 | 0.0952 | No |
| 7 | SAR1B | SAR1B Entrez, Source | SAR1 gene homolog B (S. cerevisiae) | 911 | 0.194 | 0.0979 | No |
| 8 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 956 | 0.188 | 0.1095 | No |
| 9 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 1374 | 0.145 | 0.0895 | No |
| 10 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 1409 | 0.142 | 0.0982 | No |
| 11 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 1478 | 0.137 | 0.1039 | No |
| 12 | DCLRE1B | DCLRE1B Entrez, Source | DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) | 1538 | 0.132 | 0.1100 | No |
| 13 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 1815 | 0.116 | 0.0984 | No |
| 14 | RNF41 | RNF41 Entrez, Source | ring finger protein 41 | 1847 | 0.115 | 0.1051 | No |
| 15 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 1996 | 0.108 | 0.1025 | No |
| 16 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 2337 | 0.094 | 0.0843 | No |
| 17 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 2681 | 0.081 | 0.0648 | No |
| 18 | MKKS | MKKS Entrez, Source | McKusick-Kaufman syndrome | 2877 | 0.075 | 0.0560 | No |
| 19 | MCTS1 | MCTS1 Entrez, Source | malignant T cell amplified sequence 1 | 3084 | 0.069 | 0.0459 | No |
| 20 | NPTN | NPTN Entrez, Source | neuroplastin | 3133 | 0.068 | 0.0477 | No |
| 21 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.0262 | No |
| 22 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 3591 | 0.055 | 0.0222 | No |
| 23 | CENPJ | CENPJ Entrez, Source | centromere protein J | 3842 | 0.049 | 0.0072 | No |
| 24 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 3994 | 0.045 | -0.0006 | No |
| 25 | COPB2 | COPB2 Entrez, Source | coatomer protein complex, subunit beta 2 (beta prime) | 4071 | 0.043 | -0.0030 | No |
| 26 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 4289 | 0.038 | -0.0164 | No |
| 27 | MRPL37 | MRPL37 Entrez, Source | mitochondrial ribosomal protein L37 | 5437 | 0.016 | -0.1017 | No |
| 28 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 6080 | 0.004 | -0.1499 | No |
| 29 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 6273 | 0.000 | -0.1644 | No |
| 30 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.1723 | No |
| 31 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 6473 | -0.003 | -0.1790 | No |
| 32 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 6801 | -0.009 | -0.2030 | No |
| 33 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 6832 | -0.009 | -0.2045 | No |
| 34 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 6902 | -0.011 | -0.2089 | No |
| 35 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 7051 | -0.013 | -0.2191 | No |
| 36 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 7213 | -0.016 | -0.2299 | No |
| 37 | FARSLB | FARSLB Entrez, Source | phenylalanine-tRNA synthetase-like, beta subunit | 7214 | -0.016 | -0.2286 | No |
| 38 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 7235 | -0.017 | -0.2288 | No |
| 39 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 7607 | -0.024 | -0.2550 | No |
| 40 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 7694 | -0.025 | -0.2595 | No |
| 41 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 7863 | -0.028 | -0.2699 | No |
| 42 | TDP1 | TDP1 Entrez, Source | tyrosyl-DNA phosphodiesterase 1 | 7901 | -0.029 | -0.2704 | No |
| 43 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 7923 | -0.030 | -0.2696 | No |
| 44 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 7939 | -0.030 | -0.2684 | No |
| 45 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 8169 | -0.035 | -0.2829 | No |
| 46 | LYPLA2 | LYPLA2 Entrez, Source | lysophospholipase II | 8179 | -0.035 | -0.2808 | No |
| 47 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 8245 | -0.036 | -0.2828 | No |
| 48 | PCSK7 | PCSK7 Entrez, Source | proprotein convertase subtilisin/kexin type 7 | 8290 | -0.037 | -0.2832 | No |
| 49 | CDCA4 | CDCA4 Entrez, Source | cell division cycle associated 4 | 8403 | -0.039 | -0.2885 | No |
| 50 | NCLN | NCLN Entrez, Source | nicalin homolog (zebrafish) | 8405 | -0.039 | -0.2855 | No |
| 51 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 8557 | -0.043 | -0.2935 | No |
| 52 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 8586 | -0.043 | -0.2922 | No |
| 53 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 8612 | -0.044 | -0.2906 | No |
| 54 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 8638 | -0.044 | -0.2890 | No |
| 55 | RPN1 | RPN1 Entrez, Source | ribophorin I | 8815 | -0.048 | -0.2985 | No |
| 56 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 8988 | -0.052 | -0.3074 | No |
| 57 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 9128 | -0.055 | -0.3135 | No |
| 58 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 9519 | -0.063 | -0.3380 | No |
| 59 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 9639 | -0.066 | -0.3417 | No |
| 60 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 9665 | -0.067 | -0.3382 | No |
| 61 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 9688 | -0.068 | -0.3345 | No |
| 62 | STX3 | STX3 Entrez, Source | syntaxin 3 | 9898 | -0.074 | -0.3445 | No |
| 63 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10135 | -0.080 | -0.3559 | No |
| 64 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3660 | Yes |
| 65 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 10402 | -0.087 | -0.3622 | Yes |
| 66 | NLN | NLN Entrez, Source | neurolysin (metallopeptidase M3 family) | 10442 | -0.089 | -0.3581 | Yes |
| 67 | NUP35 | NUP35 Entrez, Source | nucleoporin 35kDa | 10493 | -0.090 | -0.3547 | Yes |
| 68 | LYAR | LYAR Entrez, Source | - | 10519 | -0.091 | -0.3494 | Yes |
| 69 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 10530 | -0.091 | -0.3429 | Yes |
| 70 | CEP78 | CEP78 Entrez, Source | centrosomal protein 78kDa | 10667 | -0.096 | -0.3456 | Yes |
| 71 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10984 | -0.108 | -0.3609 | Yes |
| 72 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 11009 | -0.109 | -0.3541 | Yes |
| 73 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 11106 | -0.112 | -0.3524 | Yes |
| 74 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11183 | -0.116 | -0.3490 | Yes |
| 75 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 11225 | -0.117 | -0.3428 | Yes |
| 76 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 11229 | -0.117 | -0.3337 | Yes |
| 77 | CLCF1 | CLCF1 Entrez, Source | cardiotrophin-like cytokine factor 1 | 11234 | -0.117 | -0.3247 | Yes |
| 78 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 11328 | -0.121 | -0.3221 | Yes |
| 79 | RPP40 | RPP40 Entrez, Source | ribonuclease P 40kDa subunit | 11331 | -0.122 | -0.3126 | Yes |
| 80 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 11511 | -0.130 | -0.3158 | Yes |
| 81 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 11573 | -0.132 | -0.3099 | Yes |
| 82 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 11685 | -0.137 | -0.3074 | Yes |
| 83 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 11806 | -0.145 | -0.3049 | Yes |
| 84 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 11843 | -0.147 | -0.2960 | Yes |
| 85 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 11900 | -0.150 | -0.2883 | Yes |
| 86 | ACTL6A | ACTL6A Entrez, Source | actin-like 6A | 11977 | -0.156 | -0.2816 | Yes |
| 87 | NUP93 | NUP93 Entrez, Source | nucleoporin 93kDa | 12030 | -0.159 | -0.2729 | Yes |
| 88 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.2608 | Yes |
| 89 | NUPL1 | NUPL1 Entrez, Source | nucleoporin like 1 | 12051 | -0.161 | -0.2489 | Yes |
| 90 | WDR77 | WDR77 Entrez, Source | WD repeat domain 77 | 12231 | -0.174 | -0.2486 | Yes |
| 91 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.2418 | Yes |
| 92 | MSN | MSN Entrez, Source | moesin | 12335 | -0.182 | -0.2274 | Yes |
| 93 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 12438 | -0.192 | -0.2198 | Yes |
| 94 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 12468 | -0.195 | -0.2065 | Yes |
| 95 | SMS | SMS Entrez, Source | spermine synthase | 12527 | -0.202 | -0.1948 | Yes |
| 96 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12617 | -0.213 | -0.1846 | Yes |
| 97 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 12667 | -0.220 | -0.1709 | Yes |
| 98 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12712 | -0.226 | -0.1562 | Yes |
| 99 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 12756 | -0.234 | -0.1409 | Yes |
| 100 | PDIA4 | PDIA4 Entrez, Source | protein disulfide isomerase family A, member 4 | 12902 | -0.267 | -0.1307 | Yes |
| 101 | RNF138 | RNF138 Entrez, Source | ring finger protein 138 | 13055 | -0.309 | -0.1176 | Yes |
| 102 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.0950 | Yes |
| 103 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.0700 | Yes |
| 104 | CCDC5 | CCDC5 Entrez, Source | coiled-coil domain containing 5 (spindle associated) | 13247 | -0.474 | -0.0342 | Yes |
| 105 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13268 | -0.519 | 0.0056 | Yes |
