Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | STATIN_PATHWAY_PHARMGKB |
| Enrichment Score (ES) | 0.7250904 |
| Normalized Enrichment Score (NES) | 1.7497222 |
| Nominal p-value | 0.009727626 |
| FDR q-value | 0.039647207 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 100 | 0.661 | 0.2066 | Yes |
| 2 | LPL | LPL Entrez, Source | lipoprotein lipase | 107 | 0.646 | 0.4154 | Yes |
| 3 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 383 | 0.346 | 0.5069 | Yes |
| 4 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 431 | 0.321 | 0.6072 | Yes |
| 5 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 646 | 0.246 | 0.6707 | Yes |
| 6 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1067 | 0.174 | 0.6957 | Yes |
| 7 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1319 | 0.149 | 0.7251 | Yes |
| 8 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 1882 | 0.113 | 0.7194 | No |
| 9 | APOE | APOE Entrez, Source | apolipoprotein E | 2619 | 0.083 | 0.6910 | No |
| 10 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 2888 | 0.075 | 0.6951 | No |
| 11 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 2927 | 0.073 | 0.7160 | No |
| 12 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 3238 | 0.064 | 0.7136 | No |
| 13 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 4022 | 0.044 | 0.6691 | No |
| 14 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 4204 | 0.039 | 0.6683 | No |
| 15 | LIPC | LIPC Entrez, Source | lipase, hepatic | 6430 | -0.002 | 0.5020 | No |
| 16 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 8972 | -0.051 | 0.3279 | No |
