Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | STRUCTURE_SPECIFIC_DNA_BINDING |
| Enrichment Score (ES) | -0.6333283 |
| Normalized Enrichment Score (NES) | -1.9063952 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.017994419 |
| FWER p-Value | 0.39 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 1377 | 0.144 | -0.0656 | No |
| 2 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 2663 | 0.081 | -0.1408 | No |
| 3 | FOXC2 | FOXC2 Entrez, Source | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 3027 | 0.070 | -0.1497 | No |
| 4 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 3080 | 0.069 | -0.1355 | No |
| 5 | RAD23A | RAD23A Entrez, Source | RAD23 homolog A (S. cerevisiae) | 4946 | 0.025 | -0.2690 | No |
| 6 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 5070 | 0.023 | -0.2723 | No |
| 7 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.2736 | No |
| 8 | SUB1 | SUB1 Entrez, Source | SUB1 homolog (S. cerevisiae) | 5885 | 0.007 | -0.3260 | No |
| 9 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 6213 | 0.001 | -0.3502 | No |
| 10 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 6550 | -0.005 | -0.3743 | No |
| 11 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 7399 | -0.020 | -0.4328 | No |
| 12 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 7645 | -0.024 | -0.4448 | No |
| 13 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 9175 | -0.055 | -0.5451 | No |
| 14 | IGHMBP2 | IGHMBP2 Entrez, Source | immunoglobulin mu binding protein 2 | 9982 | -0.076 | -0.5857 | No |
| 15 | SAFB | SAFB Entrez, Source | scaffold attachment factor B | 10617 | -0.094 | -0.6086 | Yes |
| 16 | MTERF | MTERF Entrez, Source | mitochondrial transcription termination factor | 10821 | -0.102 | -0.5973 | Yes |
| 17 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11266 | -0.119 | -0.5995 | Yes |
| 18 | HLF | HLF Entrez, Source | hepatic leukemia factor | 11411 | -0.125 | -0.5775 | Yes |
| 19 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.5807 | Yes |
| 20 | WBP11 | WBP11 Entrez, Source | WW domain binding protein 11 | 12119 | -0.166 | -0.5456 | Yes |
| 21 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 12139 | -0.167 | -0.5033 | Yes |
| 22 | TREX1 | TREX1 Entrez, Source | three prime repair exonuclease 1 | 12164 | -0.169 | -0.4609 | Yes |
| 23 | PNKP | PNKP Entrez, Source | polynucleotide kinase 3'-phosphatase | 12212 | -0.172 | -0.4193 | Yes |
| 24 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.3984 | Yes |
| 25 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.3414 | Yes |
| 26 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 12999 | -0.292 | -0.2670 | Yes |
| 27 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 13036 | -0.304 | -0.1901 | Yes |
| 28 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13163 | -0.372 | -0.1022 | Yes |
| 29 | APTX | APTX Entrez, Source | aprataxin | 13232 | -0.441 | 0.0083 | Yes |
