Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TAKEDA_NUP8_HOXA9_10D_DN |
| Enrichment Score (ES) | 0.674964 |
| Normalized Enrichment Score (NES) | 2.308747 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.219047E-4 |
| FWER p-Value | 0.0010 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 31 | 0.935 | 0.0611 | Yes |
| 2 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 32 | 0.925 | 0.1238 | Yes |
| 3 | CD9 | CD9 Entrez, Source | CD9 molecule | 41 | 0.871 | 0.1822 | Yes |
| 4 | CD24 | CD24 Entrez, Source | CD24 molecule | 66 | 0.745 | 0.2310 | Yes |
| 5 | RNASE1 | RNASE1 Entrez, Source | ribonuclease, RNase A family, 1 (pancreatic) | 117 | 0.624 | 0.2695 | Yes |
| 6 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 119 | 0.621 | 0.3115 | Yes |
| 7 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 140 | 0.582 | 0.3495 | Yes |
| 8 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 186 | 0.510 | 0.3807 | Yes |
| 9 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 191 | 0.498 | 0.4141 | Yes |
| 10 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 218 | 0.471 | 0.4441 | Yes |
| 11 | RASSF4 | RASSF4 Entrez, Source | Ras association (RalGDS/AF-6) domain family 4 | 219 | 0.469 | 0.4759 | Yes |
| 12 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 285 | 0.410 | 0.4988 | Yes |
| 13 | HS3ST2 | HS3ST2 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 308 | 0.394 | 0.5239 | Yes |
| 14 | TSPAN2 | TSPAN2 Entrez, Source | tetraspanin 2 | 319 | 0.384 | 0.5491 | Yes |
| 15 | ST14 | ST14 Entrez, Source | suppression of tumorigenicity 14 (colon carcinoma) | 324 | 0.378 | 0.5744 | Yes |
| 16 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 474 | 0.294 | 0.5832 | Yes |
| 17 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 484 | 0.291 | 0.6022 | Yes |
| 18 | C1QC | C1QC Entrez, Source | complement component 1, q subcomponent, C chain | 488 | 0.290 | 0.6217 | Yes |
| 19 | C1QA | C1QA Entrez, Source | complement component 1, q subcomponent, A chain | 699 | 0.236 | 0.6218 | Yes |
| 20 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 786 | 0.217 | 0.6301 | Yes |
| 21 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 818 | 0.210 | 0.6420 | Yes |
| 22 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 823 | 0.209 | 0.6559 | Yes |
| 23 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1133 | 0.167 | 0.6439 | Yes |
| 24 | PDE4DIP | PDE4DIP Entrez, Source | phosphodiesterase 4D interacting protein (myomegalin) | 1134 | 0.167 | 0.6552 | Yes |
| 25 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 1157 | 0.164 | 0.6647 | Yes |
| 26 | HS3ST1 | HS3ST1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 1203 | 0.161 | 0.6722 | Yes |
| 27 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 1411 | 0.142 | 0.6662 | Yes |
| 28 | ACP5 | ACP5 Entrez, Source | acid phosphatase 5, tartrate resistant | 1475 | 0.137 | 0.6707 | Yes |
| 29 | ACE | ACE Entrez, Source | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 1629 | 0.127 | 0.6677 | Yes |
| 30 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1647 | 0.125 | 0.6750 | Yes |
| 31 | FCER1A | FCER1A Entrez, Source | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 1840 | 0.115 | 0.6683 | No |
| 32 | TMEM45B | TMEM45B Entrez, Source | transmembrane protein 45B | 1933 | 0.110 | 0.6688 | No |
| 33 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 2159 | 0.101 | 0.6587 | No |
| 34 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 2361 | 0.093 | 0.6499 | No |
| 35 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 2423 | 0.091 | 0.6514 | No |
| 36 | APOE | APOE Entrez, Source | apolipoprotein E | 2619 | 0.083 | 0.6423 | No |
| 37 | BLNK | BLNK Entrez, Source | B-cell linker | 2743 | 0.079 | 0.6384 | No |
| 38 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 2749 | 0.079 | 0.6433 | No |
| 39 | RPS6KA2 | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 3107 | 0.068 | 0.6210 | No |
| 40 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 3208 | 0.065 | 0.6179 | No |
| 41 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 3449 | 0.059 | 0.6038 | No |
| 42 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.6056 | No |
| 43 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 3684 | 0.053 | 0.5938 | No |
| 44 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 3774 | 0.051 | 0.5905 | No |
| 45 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 4125 | 0.042 | 0.5669 | No |
| 46 | RGC32 | RGC32 Entrez, Source | - | 4200 | 0.039 | 0.5640 | No |
| 47 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 4409 | 0.036 | 0.5507 | No |
| 48 | KCNJ15 | KCNJ15 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 15 | 4470 | 0.035 | 0.5486 | No |
| 49 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 4471 | 0.035 | 0.5509 | No |
| 50 | MS4A2 | MS4A2 Entrez, Source | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 4576 | 0.032 | 0.5453 | No |
| 51 | CORO2A | CORO2A Entrez, Source | coronin, actin binding protein, 2A | 4794 | 0.028 | 0.5308 | No |
| 52 | LGMN | LGMN Entrez, Source | legumain | 4915 | 0.026 | 0.5235 | No |
| 53 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 4951 | 0.025 | 0.5225 | No |
| 54 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 5153 | 0.021 | 0.5088 | No |
| 55 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 5323 | 0.018 | 0.4973 | No |
| 56 | ACSL6 | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 5425 | 0.016 | 0.4908 | No |
| 57 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5804 | 0.009 | 0.4629 | No |
| 58 | SLC7A8 | SLC7A8 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 | 5837 | 0.008 | 0.4611 | No |
| 59 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5909 | 0.007 | 0.4562 | No |
| 60 | OLIG1 | OLIG1 Entrez, Source | oligodendrocyte transcription factor 1 | 6022 | 0.005 | 0.4480 | No |
| 61 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 6210 | 0.001 | 0.4340 | No |
| 62 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 6245 | 0.001 | 0.4315 | No |
| 63 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 6304 | -0.000 | 0.4271 | No |
| 64 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 6664 | -0.007 | 0.4005 | No |
| 65 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 6718 | -0.007 | 0.3970 | No |
| 66 | GGTA1 | GGTA1 Entrez, Source | glycoprotein, alpha-galactosyltransferase 1 | 7462 | -0.021 | 0.3424 | No |
| 67 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 7676 | -0.025 | 0.3280 | No |
| 68 | HRH4 | HRH4 Entrez, Source | histamine receptor H4 | 8273 | -0.037 | 0.2856 | No |
| 69 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 8384 | -0.039 | 0.2799 | No |
| 70 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 8519 | -0.042 | 0.2727 | No |
| 71 | CEBPE | CEBPE Entrez, Source | CCAAT/enhancer binding protein (C/EBP), epsilon | 8579 | -0.043 | 0.2711 | No |
| 72 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8752 | -0.047 | 0.2613 | No |
| 73 | PCSK5 | PCSK5 Entrez, Source | proprotein convertase subtilisin/kexin type 5 | 9890 | -0.073 | 0.1806 | No |
| 74 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 9927 | -0.075 | 0.1829 | No |
| 75 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 10260 | -0.083 | 0.1635 | No |
| 76 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 10293 | -0.084 | 0.1668 | No |
| 77 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 10344 | -0.086 | 0.1688 | No |
| 78 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 10958 | -0.107 | 0.1299 | No |
| 79 | CTSB | CTSB Entrez, Source | cathepsin B | 11060 | -0.110 | 0.1297 | No |
| 80 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 11087 | -0.111 | 0.1353 | No |
| 81 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 11830 | -0.146 | 0.0893 | No |
| 82 | SLC25A27 | SLC25A27 Entrez, Source | solute carrier family 25, member 27 | 11838 | -0.147 | 0.0987 | No |
| 83 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 12638 | -0.216 | 0.0531 | No |
