Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TAKEDA_NUP8_HOXA9_8D_DN |
| Enrichment Score (ES) | 0.6024638 |
| Normalized Enrichment Score (NES) | 2.1247418 |
| Nominal p-value | 0.0 |
| FDR q-value | 9.764624E-4 |
| FWER p-Value | 0.011 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 31 | 0.935 | 0.0586 | Yes |
| 2 | DAB2 | DAB2 Entrez, Source | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 32 | 0.925 | 0.1190 | Yes |
| 3 | CD9 | CD9 Entrez, Source | CD9 molecule | 41 | 0.871 | 0.1752 | Yes |
| 4 | CD24 | CD24 Entrez, Source | CD24 molecule | 66 | 0.745 | 0.2220 | Yes |
| 5 | RNASE1 | RNASE1 Entrez, Source | ribonuclease, RNase A family, 1 (pancreatic) | 117 | 0.624 | 0.2589 | Yes |
| 6 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 119 | 0.621 | 0.2993 | Yes |
| 7 | IL1R2 | IL1R2 Entrez, Source | interleukin 1 receptor, type II | 140 | 0.582 | 0.3358 | Yes |
| 8 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 170 | 0.532 | 0.3683 | Yes |
| 9 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 191 | 0.498 | 0.3992 | Yes |
| 10 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 285 | 0.410 | 0.4190 | Yes |
| 11 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 290 | 0.408 | 0.4453 | Yes |
| 12 | TSPAN2 | TSPAN2 Entrez, Source | tetraspanin 2 | 319 | 0.384 | 0.4682 | Yes |
| 13 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 363 | 0.357 | 0.4883 | Yes |
| 14 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 432 | 0.320 | 0.5040 | Yes |
| 15 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 474 | 0.294 | 0.5201 | Yes |
| 16 | C1QC | C1QC Entrez, Source | complement component 1, q subcomponent, C chain | 488 | 0.290 | 0.5380 | Yes |
| 17 | C1QA | C1QA Entrez, Source | complement component 1, q subcomponent, A chain | 699 | 0.236 | 0.5375 | Yes |
| 18 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 725 | 0.231 | 0.5507 | Yes |
| 19 | RAB3C | RAB3C Entrez, Source | RAB3C, member RAS oncogene family | 739 | 0.229 | 0.5646 | Yes |
| 20 | IFNGR1 | IFNGR1 Entrez, Source | interferon gamma receptor 1 | 750 | 0.226 | 0.5786 | Yes |
| 21 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 786 | 0.217 | 0.5902 | Yes |
| 22 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 807 | 0.212 | 0.6025 | Yes |
| 23 | AKAP13 | AKAP13 Entrez, Source | A kinase (PRKA) anchor protein 13 | 1136 | 0.167 | 0.5886 | No |
| 24 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 1411 | 0.142 | 0.5771 | No |
| 25 | CD200R1 | CD200R1 Entrez, Source | CD200 receptor 1 | 1557 | 0.131 | 0.5747 | No |
| 26 | ITGAM | ITGAM Entrez, Source | integrin, alpha M (complement component 3 receptor 3 subunit) | 1608 | 0.128 | 0.5793 | No |
| 27 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1647 | 0.125 | 0.5846 | No |
| 28 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 1736 | 0.120 | 0.5858 | No |
| 29 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 1856 | 0.114 | 0.5842 | No |
| 30 | LCP2 | LCP2 Entrez, Source | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 1877 | 0.113 | 0.5901 | No |
| 31 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 2544 | 0.086 | 0.5454 | No |
| 32 | ADORA3 | ADORA3 Entrez, Source | adenosine A3 receptor | 2617 | 0.083 | 0.5454 | No |
| 33 | RPS6KA2 | RPS6KA2 Entrez, Source | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 3107 | 0.068 | 0.5129 | No |
| 34 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 3176 | 0.066 | 0.5121 | No |
| 35 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 3208 | 0.065 | 0.5140 | No |
| 36 | IL3RA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 3303 | 0.063 | 0.5110 | No |
| 37 | IL10 | IL10 Entrez, Source | interleukin 10 | 3439 | 0.059 | 0.5047 | No |
| 38 | IL5RA | IL5RA Entrez, Source | interleukin 5 receptor, alpha | 3448 | 0.059 | 0.5079 | No |
| 39 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 3449 | 0.059 | 0.5118 | No |
| 40 | ST8SIA1 | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 3554 | 0.056 | 0.5076 | No |
| 41 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 3567 | 0.056 | 0.5103 | No |
| 42 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 3675 | 0.053 | 0.5057 | No |
| 43 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 3684 | 0.053 | 0.5085 | No |
| 44 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 3774 | 0.051 | 0.5051 | No |
| 45 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 4125 | 0.042 | 0.4813 | No |
| 46 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4187 | 0.040 | 0.4793 | No |
| 47 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 4471 | 0.035 | 0.4602 | No |
| 48 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 4498 | 0.034 | 0.4605 | No |
| 49 | MS4A2 | MS4A2 Entrez, Source | membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) | 4576 | 0.032 | 0.4568 | No |
| 50 | CORO2A | CORO2A Entrez, Source | coronin, actin binding protein, 2A | 4794 | 0.028 | 0.4422 | No |
| 51 | CLEC4A | CLEC4A Entrez, Source | C-type lectin domain family 4, member A | 4831 | 0.027 | 0.4413 | No |
| 52 | LGMN | LGMN Entrez, Source | legumain | 4915 | 0.026 | 0.4367 | No |
| 53 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 5153 | 0.021 | 0.4202 | No |
| 54 | C7ORF10 | C7ORF10 Entrez, Source | chromosome 7 open reading frame 10 | 5156 | 0.021 | 0.4214 | No |
| 55 | HTR2C | HTR2C Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 2C | 5202 | 0.020 | 0.4193 | No |
| 56 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 5306 | 0.019 | 0.4127 | No |
| 57 | CLU | CLU Entrez, Source | clusterin | 5443 | 0.016 | 0.4035 | No |
| 58 | UTS2 | UTS2 Entrez, Source | urotensin 2 | 5625 | 0.012 | 0.3906 | No |
| 59 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 5689 | 0.011 | 0.3866 | No |
| 60 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5804 | 0.009 | 0.3786 | No |
| 61 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 5909 | 0.007 | 0.3712 | No |
| 62 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 5982 | 0.005 | 0.3661 | No |
| 63 | SLC16A6 | SLC16A6 Entrez, Source | solute carrier family 16, member 6 (monocarboxylic acid transporter 7) | 6019 | 0.005 | 0.3637 | No |
| 64 | OLIG1 | OLIG1 Entrez, Source | oligodendrocyte transcription factor 1 | 6022 | 0.005 | 0.3639 | No |
| 65 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 6063 | 0.004 | 0.3611 | No |
| 66 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 6231 | 0.001 | 0.3485 | No |
| 67 | LFNG | LFNG Entrez, Source | lunatic fringe homolog (Drosophila) | 6252 | 0.001 | 0.3471 | No |
| 68 | C5AR1 | C5AR1 Entrez, Source | complement component 5a receptor 1 | 6304 | -0.000 | 0.3432 | No |
| 69 | JUN | JUN Entrez, Source | jun oncogene | 6649 | -0.006 | 0.3177 | No |
| 70 | CDH8 | CDH8 Entrez, Source | cadherin 8, type 2 | 6772 | -0.008 | 0.3090 | No |
| 71 | ANTXR1 | ANTXR1 Entrez, Source | anthrax toxin receptor 1 | 7631 | -0.024 | 0.2458 | No |
| 72 | RAP1A | RAP1A Entrez, Source | RAP1A, member of RAS oncogene family | 7676 | -0.025 | 0.2441 | No |
| 73 | RAP2A | RAP2A Entrez, Source | RAP2A, member of RAS oncogene family | 8205 | -0.035 | 0.2065 | No |
| 74 | HRH4 | HRH4 Entrez, Source | histamine receptor H4 | 8273 | -0.037 | 0.2038 | No |
| 75 | KCNMA1 | KCNMA1 Entrez, Source | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 8304 | -0.037 | 0.2040 | No |
| 76 | ZDHHC19 | ZDHHC19 Entrez, Source | zinc finger, DHHC-type containing 19 | 8373 | -0.039 | 0.2014 | No |
| 77 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 8384 | -0.039 | 0.2032 | No |
| 78 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 8519 | -0.042 | 0.1958 | No |
| 79 | CEBPE | CEBPE Entrez, Source | CCAAT/enhancer binding protein (C/EBP), epsilon | 8579 | -0.043 | 0.1942 | No |
| 80 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 8582 | -0.043 | 0.1968 | No |
| 81 | ADAM19 | ADAM19 Entrez, Source | ADAM metallopeptidase domain 19 (meltrin beta) | 8788 | -0.048 | 0.1844 | No |
| 82 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 8893 | -0.050 | 0.1798 | No |
| 83 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9465 | -0.062 | 0.1407 | No |
| 84 | CYBB | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 9683 | -0.067 | 0.1287 | No |
| 85 | HTRA1 | HTRA1 Entrez, Source | HtrA serine peptidase 1 | 9698 | -0.068 | 0.1321 | No |
| 86 | PCSK5 | PCSK5 Entrez, Source | proprotein convertase subtilisin/kexin type 5 | 9890 | -0.073 | 0.1225 | No |
| 87 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 9944 | -0.075 | 0.1234 | No |
| 88 | PPP1R3B | PPP1R3B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3B | 10143 | -0.080 | 0.1136 | No |
| 89 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 10293 | -0.084 | 0.1079 | No |
| 90 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 10344 | -0.086 | 0.1097 | No |
| 91 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 10420 | -0.088 | 0.1097 | No |
| 92 | UHMK1 | UHMK1 Entrez, Source | U2AF homology motif (UHM) kinase 1 | 10926 | -0.106 | 0.0785 | No |
| 93 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 10958 | -0.107 | 0.0831 | No |
| 94 | CTSB | CTSB Entrez, Source | cathepsin B | 11060 | -0.110 | 0.0827 | No |
| 95 | FCGR2B | FCGR2B Entrez, Source | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 11337 | -0.122 | 0.0698 | No |
| 96 | SLC30A7 | SLC30A7 Entrez, Source | solute carrier family 30 (zinc transporter), member 7 | 11436 | -0.126 | 0.0706 | No |
| 97 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 11464 | -0.127 | 0.0769 | No |
| 98 | COLEC12 | COLEC12 Entrez, Source | collectin sub-family member 12 | 11746 | -0.141 | 0.0649 | No |
| 99 | SLC25A27 | SLC25A27 Entrez, Source | solute carrier family 25, member 27 | 11838 | -0.147 | 0.0676 | No |
| 100 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 11894 | -0.150 | 0.0732 | No |
| 101 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12248 | -0.175 | 0.0580 | No |
| 102 | C1ORF24 | C1ORF24 Entrez, Source | chromosome 1 open reading frame 24 | 12324 | -0.182 | 0.0641 | No |
| 103 | CD14 | CD14 Entrez, Source | CD14 molecule | 12462 | -0.194 | 0.0665 | No |
