Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | 0.5686832 |
| Normalized Enrichment Score (NES) | 1.7098638 |
| Nominal p-value | 0.011235955 |
| FDR q-value | 0.052476455 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12 | 1.254 | 0.1852 | Yes |
| 2 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 43 | 0.843 | 0.3080 | Yes |
| 3 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 321 | 0.383 | 0.3439 | Yes |
| 4 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 337 | 0.371 | 0.3978 | Yes |
| 5 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 480 | 0.292 | 0.4305 | Yes |
| 6 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 533 | 0.274 | 0.4673 | Yes |
| 7 | PXN | PXN Entrez, Source | paxillin | 594 | 0.258 | 0.5010 | Yes |
| 8 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 643 | 0.247 | 0.5340 | Yes |
| 9 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 818 | 0.210 | 0.5521 | Yes |
| 10 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 1095 | 0.171 | 0.5568 | Yes |
| 11 | FN1 | FN1 Entrez, Source | fibronectin 1 | 1246 | 0.156 | 0.5687 | Yes |
| 12 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1556 | 0.131 | 0.5649 | No |
| 13 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 1797 | 0.117 | 0.5642 | No |
| 14 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2072 | 0.105 | 0.5592 | No |
| 15 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 2357 | 0.093 | 0.5517 | No |
| 16 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 3176 | 0.066 | 0.5000 | No |
| 17 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 4204 | 0.039 | 0.4287 | No |
| 18 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 4364 | 0.036 | 0.4222 | No |
| 19 | NID1 | NID1 Entrez, Source | nidogen 1 | 4891 | 0.026 | 0.3865 | No |
| 20 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 5411 | 0.016 | 0.3500 | No |
| 21 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 6450 | -0.003 | 0.2723 | No |
| 22 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 6591 | -0.005 | 0.2626 | No |
| 23 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 6668 | -0.007 | 0.2579 | No |
| 24 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 7282 | -0.018 | 0.2144 | No |
| 25 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 7897 | -0.029 | 0.1726 | No |
| 26 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 8243 | -0.036 | 0.1520 | No |
| 27 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 9259 | -0.057 | 0.0842 | No |
| 28 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9465 | -0.062 | 0.0780 | No |
| 29 | JUP | JUP Entrez, Source | junction plakoglobin | 9963 | -0.075 | 0.0518 | No |
| 30 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 10160 | -0.081 | 0.0490 | No |
| 31 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 10241 | -0.083 | 0.0553 | No |
| 32 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 10475 | -0.090 | 0.0511 | No |
| 33 | ZYX | ZYX Entrez, Source | zyxin | 10834 | -0.102 | 0.0393 | No |
| 34 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 11461 | -0.127 | 0.0112 | No |
| 35 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 11482 | -0.128 | 0.0287 | No |
| 36 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 12747 | -0.232 | -0.0318 | No |
| 37 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 12780 | -0.238 | 0.0011 | No |
| 38 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 12951 | -0.277 | 0.0294 | No |
