Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TISSUE_DEVELOPMENT |
| Enrichment Score (ES) | 0.5913239 |
| Normalized Enrichment Score (NES) | 1.9542191 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0078215 |
| FWER p-Value | 0.285 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 23 | 1.021 | 0.0906 | Yes |
| 2 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.1699 | Yes |
| 3 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 61 | 0.759 | 0.2369 | Yes |
| 4 | MGP | MGP Entrez, Source | matrix Gla protein | 108 | 0.644 | 0.2916 | Yes |
| 5 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 119 | 0.621 | 0.3471 | Yes |
| 6 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 171 | 0.530 | 0.3912 | Yes |
| 7 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 255 | 0.437 | 0.4245 | Yes |
| 8 | BTD | BTD Entrez, Source | biotinidase | 427 | 0.322 | 0.4407 | Yes |
| 9 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 480 | 0.292 | 0.4632 | Yes |
| 10 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 525 | 0.277 | 0.4850 | Yes |
| 11 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 526 | 0.277 | 0.5100 | Yes |
| 12 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 530 | 0.275 | 0.5347 | Yes |
| 13 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 561 | 0.267 | 0.5565 | Yes |
| 14 | FST | FST Entrez, Source | follistatin | 678 | 0.240 | 0.5695 | Yes |
| 15 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.5691 | Yes |
| 16 | KL | KL Entrez, Source | klotho | 971 | 0.186 | 0.5819 | Yes |
| 17 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 1105 | 0.170 | 0.5872 | Yes |
| 18 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 1240 | 0.157 | 0.5913 | Yes |
| 19 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1486 | 0.136 | 0.5852 | No |
| 20 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1870 | 0.113 | 0.5666 | No |
| 21 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 2041 | 0.106 | 0.5633 | No |
| 22 | DSPP | DSPP Entrez, Source | dentin sialophosphoprotein | 2163 | 0.101 | 0.5634 | No |
| 23 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 2250 | 0.097 | 0.5657 | No |
| 24 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 2467 | 0.089 | 0.5575 | No |
| 25 | TWIST2 | TWIST2 Entrez, Source | twist homolog 2 (Drosophila) | 2757 | 0.078 | 0.5428 | No |
| 26 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 2907 | 0.074 | 0.5382 | No |
| 27 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 2981 | 0.072 | 0.5392 | No |
| 28 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 3188 | 0.066 | 0.5297 | No |
| 29 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 3344 | 0.061 | 0.5236 | No |
| 30 | ATP2C1 | ATP2C1 Entrez, Source | ATPase, Ca++ transporting, type 2C, member 1 | 3361 | 0.061 | 0.5279 | No |
| 31 | POU2F3 | POU2F3 Entrez, Source | POU domain, class 2, transcription factor 3 | 3508 | 0.057 | 0.5221 | No |
| 32 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 3725 | 0.052 | 0.5105 | No |
| 33 | PTF1A | PTF1A Entrez, Source | pancreas specific transcription factor, 1a | 4139 | 0.041 | 0.4831 | No |
| 34 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 4246 | 0.039 | 0.4786 | No |
| 35 | SLIT2 | SLIT2 Entrez, Source | slit homolog 2 (Drosophila) | 4330 | 0.037 | 0.4757 | No |
| 36 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 4595 | 0.032 | 0.4587 | No |
| 37 | EYA2 | EYA2 Entrez, Source | eyes absent homolog 2 (Drosophila) | 4619 | 0.032 | 0.4598 | No |
| 38 | GDF11 | GDF11 Entrez, Source | growth differentiation factor 11 | 5121 | 0.022 | 0.4241 | No |
| 39 | VAX2 | VAX2 Entrez, Source | ventral anterior homeobox 2 | 5163 | 0.021 | 0.4229 | No |
| 40 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 5384 | 0.017 | 0.4078 | No |
| 41 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 5532 | 0.014 | 0.3980 | No |
| 42 | DMP1 | DMP1 Entrez, Source | dentin matrix acidic phosphoprotein | 5545 | 0.014 | 0.3984 | No |
| 43 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 5869 | 0.008 | 0.3748 | No |
| 44 | CASR | CASR Entrez, Source | calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism) | 6039 | 0.004 | 0.3624 | No |
| 45 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 6140 | 0.002 | 0.3551 | No |
| 46 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 6213 | 0.001 | 0.3498 | No |
| 47 | GLI1 | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 6239 | 0.001 | 0.3480 | No |
| 48 | IL17F | IL17F Entrez, Source | interleukin 17F | 6554 | -0.005 | 0.3247 | No |
| 49 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 6563 | -0.005 | 0.3246 | No |
| 50 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 6711 | -0.007 | 0.3142 | No |
| 51 | DSP | DSP Entrez, Source | desmoplakin | 7304 | -0.018 | 0.2712 | No |
| 52 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 7366 | -0.019 | 0.2683 | No |
| 53 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 7391 | -0.020 | 0.2683 | No |
| 54 | SECTM1 | SECTM1 Entrez, Source | secreted and transmembrane 1 | 7983 | -0.031 | 0.2266 | No |
| 55 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 8426 | -0.040 | 0.1969 | No |
| 56 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 8616 | -0.044 | 0.1866 | No |
| 57 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 8632 | -0.044 | 0.1894 | No |
| 58 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 8917 | -0.050 | 0.1726 | No |
| 59 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 9852 | -0.072 | 0.1088 | No |
| 60 | ERCC3 | ERCC3 Entrez, Source | excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) | 10351 | -0.086 | 0.0790 | No |
| 61 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 10565 | -0.092 | 0.0713 | No |
| 62 | OSTF1 | OSTF1 Entrez, Source | osteoclast stimulating factor 1 | 10866 | -0.104 | 0.0581 | No |
| 63 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 11225 | -0.117 | 0.0417 | No |
| 64 | PLOD1 | PLOD1 Entrez, Source | procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 | 11305 | -0.121 | 0.0467 | No |
| 65 | KLK7 | KLK7 Entrez, Source | kallikrein 7 (chymotryptic, stratum corneum) | 11392 | -0.124 | 0.0514 | No |
| 66 | STX2 | STX2 Entrez, Source | syntaxin 2 | 11621 | -0.135 | 0.0464 | No |
| 67 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13211 | -0.414 | -0.0358 | No |
| 68 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 13259 | -0.504 | 0.0063 | No |
