Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TNFALPHA_ADIP_DN |
| Enrichment Score (ES) | 0.5761197 |
| Normalized Enrichment Score (NES) | 1.7853765 |
| Nominal p-value | 0.0035906644 |
| FDR q-value | 0.03144812 |
| FWER p-Value | 0.968 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 47 | 0.829 | 0.0950 | Yes |
| 2 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 50 | 0.810 | 0.1911 | Yes |
| 3 | PEX11A | PEX11A Entrez, Source | peroxisomal biogenesis factor 11A | 86 | 0.682 | 0.2696 | Yes |
| 4 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 167 | 0.536 | 0.3273 | Yes |
| 5 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 258 | 0.431 | 0.3718 | Yes |
| 6 | PC | PC Entrez, Source | pyruvate carboxylase | 322 | 0.380 | 0.4123 | Yes |
| 7 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 336 | 0.371 | 0.4554 | Yes |
| 8 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 350 | 0.365 | 0.4978 | Yes |
| 9 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 431 | 0.321 | 0.5299 | Yes |
| 10 | RASD1 | RASD1 Entrez, Source | RAS, dexamethasone-induced 1 | 651 | 0.245 | 0.5426 | Yes |
| 11 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 992 | 0.183 | 0.5388 | Yes |
| 12 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1067 | 0.174 | 0.5540 | Yes |
| 13 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 1135 | 0.167 | 0.5688 | Yes |
| 14 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1544 | 0.132 | 0.5538 | Yes |
| 15 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 1627 | 0.127 | 0.5626 | Yes |
| 16 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1647 | 0.125 | 0.5761 | Yes |
| 17 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 1969 | 0.109 | 0.5649 | No |
| 18 | FASN | FASN Entrez, Source | fatty acid synthase | 2099 | 0.104 | 0.5676 | No |
| 19 | NFS1 | NFS1 Entrez, Source | NFS1 nitrogen fixation 1 (S. cerevisiae) | 2570 | 0.085 | 0.5423 | No |
| 20 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 2947 | 0.073 | 0.5227 | No |
| 21 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3161 | 0.067 | 0.5146 | No |
| 22 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 3794 | 0.050 | 0.4730 | No |
| 23 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 4228 | 0.039 | 0.4451 | No |
| 24 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 4838 | 0.027 | 0.4026 | No |
| 25 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 5216 | 0.020 | 0.3766 | No |
| 26 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 5283 | 0.019 | 0.3739 | No |
| 27 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6502 | -0.004 | 0.2828 | No |
| 28 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 6599 | -0.006 | 0.2762 | No |
| 29 | TALDO1 | TALDO1 Entrez, Source | transaldolase 1 | 6671 | -0.007 | 0.2717 | No |
| 30 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 6979 | -0.012 | 0.2500 | No |
| 31 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 7051 | -0.013 | 0.2462 | No |
| 32 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 7244 | -0.017 | 0.2338 | No |
| 33 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 9245 | -0.057 | 0.0902 | No |
| 34 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 9342 | -0.059 | 0.0900 | No |
| 35 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 9476 | -0.062 | 0.0874 | No |
| 36 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 9995 | -0.076 | 0.0576 | No |
| 37 | FAM62A | FAM62A Entrez, Source | family with sequence similarity 62 (C2 domain containing), member A | 10256 | -0.083 | 0.0479 | No |
| 38 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 10393 | -0.087 | 0.0480 | No |
| 39 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | 0.0532 | No |
| 40 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12528 | -0.202 | -0.0777 | No |
| 41 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13097 | -0.326 | -0.0817 | No |
| 42 | ENTPD5 | ENTPD5 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 5 | 13183 | -0.385 | -0.0423 | No |
| 43 | HIPK3 | HIPK3 Entrez, Source | homeodomain interacting protein kinase 3 | 13242 | -0.455 | 0.0075 | No |
