Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.6407668 |
| Normalized Enrichment Score (NES) | 1.7206669 |
| Nominal p-value | 0.0076045627 |
| FDR q-value | 0.04908874 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 76 | 0.697 | 0.1421 | Yes |
| 2 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 77 | 0.697 | 0.2899 | Yes |
| 3 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 138 | 0.591 | 0.4108 | Yes |
| 4 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 232 | 0.457 | 0.5008 | Yes |
| 5 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 329 | 0.374 | 0.5728 | Yes |
| 6 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 390 | 0.341 | 0.6408 | Yes |
| 7 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 1428 | 0.140 | 0.5927 | No |
| 8 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1531 | 0.133 | 0.6131 | No |
| 9 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 2159 | 0.101 | 0.5875 | No |
| 10 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 2208 | 0.099 | 0.6049 | No |
| 11 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 2692 | 0.081 | 0.5857 | No |
| 12 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 3774 | 0.051 | 0.5153 | No |
| 13 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 4249 | 0.038 | 0.4879 | No |
| 14 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 4448 | 0.035 | 0.4804 | No |
| 15 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 4624 | 0.032 | 0.4740 | No |
| 16 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 5594 | 0.013 | 0.4039 | No |
| 17 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 6269 | 0.000 | 0.3534 | No |
| 18 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 6481 | -0.003 | 0.3382 | No |
| 19 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6589 | -0.005 | 0.3313 | No |
| 20 | TPO | TPO Entrez, Source | thyroid peroxidase | 7149 | -0.015 | 0.2925 | No |
| 21 | TH | TH Entrez, Source | tyrosine hydroxylase | 7473 | -0.021 | 0.2727 | No |
| 22 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 9641 | -0.066 | 0.1241 | No |
| 23 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 11040 | -0.109 | 0.0424 | No |
| 24 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 13304 | -0.615 | 0.0029 | No |
