Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | UVC_XPCS_4HR_DN |
| Enrichment Score (ES) | -0.35178778 |
| Normalized Enrichment Score (NES) | -1.3308616 |
| Nominal p-value | 0.041769043 |
| FDR q-value | 0.37865108 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 37 | 0.888 | 0.0680 | No |
| 2 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 217 | 0.472 | 0.0920 | No |
| 3 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 807 | 0.212 | 0.0644 | No |
| 4 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.0717 | No |
| 5 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 933 | 0.190 | 0.0856 | No |
| 6 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 956 | 0.188 | 0.0989 | No |
| 7 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1043 | 0.177 | 0.1065 | No |
| 8 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 1062 | 0.175 | 0.1191 | No |
| 9 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 1300 | 0.150 | 0.1132 | No |
| 10 | SOS2 | SOS2 Entrez, Source | son of sevenless homolog 2 (Drosophila) | 1312 | 0.149 | 0.1243 | No |
| 11 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 1410 | 0.142 | 0.1283 | No |
| 12 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 1427 | 0.140 | 0.1382 | No |
| 13 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1511 | 0.134 | 0.1427 | No |
| 14 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 1722 | 0.122 | 0.1365 | No |
| 15 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 1932 | 0.110 | 0.1295 | No |
| 16 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 1951 | 0.110 | 0.1369 | No |
| 17 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 2116 | 0.103 | 0.1327 | No |
| 18 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 2271 | 0.097 | 0.1288 | No |
| 19 | GLRB | GLRB Entrez, Source | glycine receptor, beta | 2470 | 0.089 | 0.1209 | No |
| 20 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 2623 | 0.083 | 0.1161 | No |
| 21 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 2756 | 0.078 | 0.1123 | No |
| 22 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 3004 | 0.071 | 0.0993 | No |
| 23 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 3113 | 0.068 | 0.0966 | No |
| 24 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 3210 | 0.065 | 0.0946 | No |
| 25 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 3472 | 0.058 | 0.0795 | No |
| 26 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 3506 | 0.057 | 0.0816 | No |
| 27 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 3561 | 0.056 | 0.0820 | No |
| 28 | ZHX3 | ZHX3 Entrez, Source | zinc fingers and homeoboxes 3 | 3677 | 0.053 | 0.0775 | No |
| 29 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 3890 | 0.048 | 0.0653 | No |
| 30 | BTRC | BTRC Entrez, Source | beta-transducin repeat containing | 4316 | 0.037 | 0.0361 | No |
| 31 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 4502 | 0.034 | 0.0249 | No |
| 32 | NFIB | NFIB Entrez, Source | nuclear factor I/B | 4797 | 0.028 | 0.0049 | No |
| 33 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5213 | 0.020 | -0.0248 | No |
| 34 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 5285 | 0.019 | -0.0287 | No |
| 35 | BMPR1A | BMPR1A Entrez, Source | bone morphogenetic protein receptor, type IA | 5309 | 0.019 | -0.0289 | No |
| 36 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 5384 | 0.017 | -0.0332 | No |
| 37 | KLF6 | KLF6 Entrez, Source | Kruppel-like factor 6 | 5447 | 0.016 | -0.0366 | No |
| 38 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 5786 | 0.009 | -0.0614 | No |
| 39 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 5813 | 0.009 | -0.0626 | No |
| 40 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 5997 | 0.005 | -0.0760 | No |
| 41 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 6465 | -0.003 | -0.1111 | No |
| 42 | AFAP | AFAP Entrez, Source | - | 6545 | -0.005 | -0.1167 | No |
| 43 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 6645 | -0.006 | -0.1236 | No |
| 44 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 6711 | -0.007 | -0.1279 | No |
| 45 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 6744 | -0.008 | -0.1297 | No |
| 46 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 7364 | -0.019 | -0.1750 | No |
| 47 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 7518 | -0.022 | -0.1848 | No |
| 48 | CENTB2 | CENTB2 Entrez, Source | centaurin, beta 2 | 7595 | -0.023 | -0.1886 | No |
| 49 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 7785 | -0.027 | -0.2008 | No |
| 50 | PARG | PARG Entrez, Source | poly (ADP-ribose) glycohydrolase | 7997 | -0.031 | -0.2142 | No |
| 51 | MTMR3 | MTMR3 Entrez, Source | myotubularin related protein 3 | 8330 | -0.038 | -0.2363 | No |
| 52 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 8342 | -0.038 | -0.2340 | No |
| 53 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 8548 | -0.042 | -0.2461 | No |
| 54 | WNT5A | WNT5A Entrez, Source | wingless-type MMTV integration site family, member 5A | 8849 | -0.049 | -0.2649 | No |
| 55 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 9058 | -0.053 | -0.2764 | No |
| 56 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 9095 | -0.054 | -0.2748 | No |
| 57 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 9463 | -0.062 | -0.2976 | No |
| 58 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 9765 | -0.070 | -0.3148 | No |
| 59 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 9817 | -0.071 | -0.3129 | No |
| 60 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 9971 | -0.076 | -0.3185 | No |
| 61 | MTF2 | MTF2 Entrez, Source | metal response element binding transcription factor 2 | 10257 | -0.083 | -0.3334 | No |
| 62 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 10272 | -0.084 | -0.3277 | No |
| 63 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 10350 | -0.086 | -0.3267 | No |
| 64 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 10356 | -0.086 | -0.3202 | No |
| 65 | PRR3 | PRR3 Entrez, Source | proline rich 3 | 10589 | -0.093 | -0.3303 | No |
| 66 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 10767 | -0.100 | -0.3358 | No |
| 67 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 10775 | -0.100 | -0.3283 | No |
| 68 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 11078 | -0.111 | -0.3423 | No |
| 69 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 11205 | -0.116 | -0.3425 | Yes |
| 70 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11215 | -0.117 | -0.3339 | Yes |
| 71 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 11303 | -0.121 | -0.3309 | Yes |
| 72 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 11387 | -0.124 | -0.3272 | Yes |
| 73 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 11464 | -0.127 | -0.3228 | Yes |
| 74 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 11792 | -0.144 | -0.3360 | Yes |
| 75 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 11793 | -0.144 | -0.3246 | Yes |
| 76 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 11805 | -0.145 | -0.3139 | Yes |
| 77 | RBM39 | RBM39 Entrez, Source | RNA binding motif protein 39 | 11924 | -0.152 | -0.3107 | Yes |
| 78 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11979 | -0.156 | -0.3024 | Yes |
| 79 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 12170 | -0.169 | -0.3032 | Yes |
| 80 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.2951 | Yes |
| 81 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 12272 | -0.177 | -0.2827 | Yes |
| 82 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 12366 | -0.185 | -0.2749 | Yes |
| 83 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 12529 | -0.202 | -0.2710 | Yes |
| 84 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 12547 | -0.204 | -0.2561 | Yes |
| 85 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 12589 | -0.209 | -0.2425 | Yes |
| 86 | MECP2 | MECP2 Entrez, Source | methyl CpG binding protein 2 (Rett syndrome) | 12609 | -0.212 | -0.2270 | Yes |
| 87 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 12642 | -0.216 | -0.2122 | Yes |
| 88 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 12656 | -0.218 | -0.1958 | Yes |
| 89 | EDD1 | EDD1 Entrez, Source | E3 ubiquitin protein ligase, HECT domain containing, 1 | 12711 | -0.226 | -0.1819 | Yes |
| 90 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 12721 | -0.227 | -0.1644 | Yes |
| 91 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12847 | -0.253 | -0.1537 | Yes |
| 92 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 12874 | -0.260 | -0.1350 | Yes |
| 93 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12946 | -0.276 | -0.1184 | Yes |
| 94 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 13021 | -0.298 | -0.1002 | Yes |
| 95 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 13036 | -0.304 | -0.0770 | Yes |
| 96 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 13038 | -0.305 | -0.0528 | Yes |
| 97 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 13043 | -0.306 | -0.0287 | Yes |
| 98 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 13083 | -0.319 | -0.0062 | Yes |
| 99 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 13090 | -0.322 | 0.0190 | Yes |
