Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | V$AML1_Q6 |
| Enrichment Score (ES) | 0.46850973 |
| Normalized Enrichment Score (NES) | 1.6993928 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.055300295 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 2 | 1.623 | 0.1065 | Yes |
| 2 | VIM | VIM Entrez, Source | vimentin | 7 | 1.391 | 0.1975 | Yes |
| 3 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 56 | 0.784 | 0.2454 | Yes |
| 4 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 73 | 0.715 | 0.2912 | Yes |
| 5 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 89 | 0.680 | 0.3347 | Yes |
| 6 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 119 | 0.621 | 0.3733 | Yes |
| 7 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 188 | 0.507 | 0.4015 | Yes |
| 8 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 312 | 0.390 | 0.4178 | Yes |
| 9 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 363 | 0.357 | 0.4375 | Yes |
| 10 | PXN | PXN Entrez, Source | paxillin | 594 | 0.258 | 0.4370 | Yes |
| 11 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 623 | 0.251 | 0.4514 | Yes |
| 12 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 724 | 0.231 | 0.4590 | Yes |
| 13 | PRICKLE1 | PRICKLE1 Entrez, Source | prickle homolog 1 (Drosophila) | 927 | 0.191 | 0.4563 | Yes |
| 14 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 932 | 0.190 | 0.4685 | Yes |
| 15 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 1525 | 0.133 | 0.4325 | No |
| 16 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1785 | 0.118 | 0.4207 | No |
| 17 | PDE6H | PDE6H Entrez, Source | phosphodiesterase 6H, cGMP-specific, cone, gamma | 1813 | 0.116 | 0.4263 | No |
| 18 | CHRNA10 | CHRNA10 Entrez, Source | cholinergic receptor, nicotinic, alpha 10 | 2034 | 0.106 | 0.4166 | No |
| 19 | SCN8A | SCN8A Entrez, Source | sodium channel, voltage gated, type VIII, alpha | 2420 | 0.091 | 0.3935 | No |
| 20 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 2422 | 0.091 | 0.3993 | No |
| 21 | RIN1 | RIN1 Entrez, Source | Ras and Rab interactor 1 | 2457 | 0.089 | 0.4027 | No |
| 22 | PACS1 | PACS1 Entrez, Source | phosphofurin acidic cluster sorting protein 1 | 2976 | 0.072 | 0.3682 | No |
| 23 | ANXA8 | ANXA8 Entrez, Source | annexin A8 | 3018 | 0.071 | 0.3698 | No |
| 24 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 3037 | 0.070 | 0.3730 | No |
| 25 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 3176 | 0.066 | 0.3669 | No |
| 26 | NGB | NGB Entrez, Source | neuroglobin | 3212 | 0.065 | 0.3686 | No |
| 27 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 3414 | 0.060 | 0.3573 | No |
| 28 | PTK9 | PTK9 Entrez, Source | PTK9 protein tyrosine kinase 9 | 3426 | 0.060 | 0.3604 | No |
| 29 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 3429 | 0.060 | 0.3642 | No |
| 30 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.3643 | No |
| 31 | MATN1 | MATN1 Entrez, Source | matrilin 1, cartilage matrix protein | 3617 | 0.054 | 0.3575 | No |
| 32 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 3635 | 0.054 | 0.3598 | No |
| 33 | DNM3 | DNM3 Entrez, Source | dynamin 3 | 3690 | 0.053 | 0.3592 | No |
| 34 | AKAP3 | AKAP3 Entrez, Source | A kinase (PRKA) anchor protein 3 | 3973 | 0.045 | 0.3408 | No |
| 35 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 4049 | 0.043 | 0.3380 | No |
| 36 | GRASP | GRASP Entrez, Source | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | 4059 | 0.043 | 0.3401 | No |
| 37 | CRTAC1 | CRTAC1 Entrez, Source | cartilage acidic protein 1 | 4077 | 0.043 | 0.3417 | No |
| 38 | DIABLO | DIABLO Entrez, Source | diablo homolog (Drosophila) | 4276 | 0.038 | 0.3292 | No |
| 39 | AGTRL1 | AGTRL1 Entrez, Source | angiotensin II receptor-like 1 | 4285 | 0.038 | 0.3311 | No |
| 40 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 4364 | 0.036 | 0.3276 | No |
| 41 | ARF3 | ARF3 Entrez, Source | ADP-ribosylation factor 3 | 4689 | 0.030 | 0.3051 | No |
| 42 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 4853 | 0.027 | 0.2945 | No |
| 43 | IFNG | IFNG Entrez, Source | interferon, gamma | 4856 | 0.027 | 0.2962 | No |
| 44 | LUZP1 | LUZP1 Entrez, Source | leucine zipper protein 1 | 4920 | 0.026 | 0.2931 | No |
| 45 | DAB1 | DAB1 Entrez, Source | disabled homolog 1 (Drosophila) | 4974 | 0.025 | 0.2907 | No |
| 46 | TBX5 | TBX5 Entrez, Source | T-box 5 | 5141 | 0.021 | 0.2795 | No |
| 47 | TNFSF4 | TNFSF4 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) | 5262 | 0.019 | 0.2718 | No |
| 48 | SNX1 | SNX1 Entrez, Source | sorting nexin 1 | 5489 | 0.015 | 0.2557 | No |
| 49 | SCN2B | SCN2B Entrez, Source | sodium channel, voltage-gated, type II, beta | 5632 | 0.012 | 0.2457 | No |
| 50 | BTG4 | BTG4 Entrez, Source | B-cell translocation gene 4 | 5638 | 0.012 | 0.2461 | No |
| 51 | XCL1 | XCL1 Entrez, Source | chemokine (C motif) ligand 1 | 5671 | 0.012 | 0.2445 | No |
| 52 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 5770 | 0.010 | 0.2377 | No |
| 53 | BLOC1S2 | BLOC1S2 Entrez, Source | biogenesis of lysosome-related organelles complex-1, subunit 2 | 5964 | 0.006 | 0.2235 | No |
| 54 | GPATC2 | GPATC2 Entrez, Source | G patch domain containing 2 | 6105 | 0.003 | 0.2131 | No |
| 55 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 6112 | 0.003 | 0.2129 | No |
| 56 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 6231 | 0.001 | 0.2040 | No |
| 57 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 6245 | 0.001 | 0.2031 | No |
| 58 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 6293 | -0.000 | 0.1995 | No |
| 59 | DNAJC14 | DNAJC14 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 14 | 6403 | -0.002 | 0.1914 | No |
| 60 | SCN3B | SCN3B Entrez, Source | sodium channel, voltage-gated, type III, beta | 6438 | -0.002 | 0.1890 | No |
| 61 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 6582 | -0.005 | 0.1785 | No |
| 62 | LMO2 | LMO2 Entrez, Source | LIM domain only 2 (rhombotin-like 1) | 6756 | -0.008 | 0.1660 | No |
| 63 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 6918 | -0.011 | 0.1545 | No |
| 64 | PSMA1 | PSMA1 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 1 | 6962 | -0.012 | 0.1521 | No |
| 65 | MYOD1 | MYOD1 Entrez, Source | myogenic differentiation 1 | 7147 | -0.015 | 0.1391 | No |
| 66 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 7341 | -0.019 | 0.1257 | No |
| 67 | CD6 | CD6 Entrez, Source | CD6 molecule | 7354 | -0.019 | 0.1261 | No |
| 68 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 7553 | -0.023 | 0.1126 | No |
| 69 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 7565 | -0.023 | 0.1133 | No |
| 70 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | 0.1024 | No |
| 71 | KCNJ1 | KCNJ1 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 1 | 7754 | -0.026 | 0.1026 | No |
| 72 | SLC6A9 | SLC6A9 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 7789 | -0.027 | 0.1018 | No |
| 73 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 7810 | -0.028 | 0.1021 | No |
| 74 | SLC12A6 | SLC12A6 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 6 | 8133 | -0.034 | 0.0800 | No |
| 75 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 8462 | -0.041 | 0.0579 | No |
| 76 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 8475 | -0.041 | 0.0596 | No |
| 77 | ACIN1 | ACIN1 Entrez, Source | apoptotic chromatin condensation inducer 1 | 8577 | -0.043 | 0.0548 | No |
| 78 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 8582 | -0.043 | 0.0574 | No |
| 79 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 8616 | -0.044 | 0.0577 | No |
| 80 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 8635 | -0.044 | 0.0593 | No |
| 81 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 8658 | -0.045 | 0.0605 | No |
| 82 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 8718 | -0.046 | 0.0591 | No |
| 83 | SCNN1A | SCNN1A Entrez, Source | sodium channel, nonvoltage-gated 1 alpha | 8793 | -0.048 | 0.0566 | No |
| 84 | CREM | CREM Entrez, Source | cAMP responsive element modulator | 8985 | -0.051 | 0.0456 | No |
| 85 | CTSK | CTSK Entrez, Source | cathepsin K (pycnodysostosis) | 8999 | -0.052 | 0.0480 | No |
| 86 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 9146 | -0.055 | 0.0406 | No |
| 87 | FGF4 | FGF4 Entrez, Source | fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene) | 9186 | -0.056 | 0.0413 | No |
| 88 | SEMA4A | SEMA4A Entrez, Source | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 9266 | -0.057 | 0.0391 | No |
| 89 | EIF2B3 | EIF2B3 Entrez, Source | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 9514 | -0.063 | 0.0245 | No |
| 90 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 9634 | -0.066 | 0.0199 | No |
| 91 | SLC15A3 | SLC15A3 Entrez, Source | solute carrier family 15, member 3 | 9719 | -0.069 | 0.0180 | No |
| 92 | MADD | MADD Entrez, Source | MAP-kinase activating death domain | 10009 | -0.077 | 0.0013 | No |
| 93 | INPPL1 | INPPL1 Entrez, Source | inositol polyphosphate phosphatase-like 1 | 10072 | -0.079 | 0.0017 | No |
| 94 | MAMDC1 | MAMDC1 Entrez, Source | MAM domain containing 1 | 10078 | -0.079 | 0.0065 | No |
| 95 | STAT2 | STAT2 Entrez, Source | signal transducer and activator of transcription 2, 113kDa | 10630 | -0.095 | -0.0289 | No |
| 96 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 10684 | -0.097 | -0.0266 | No |
| 97 | PTPN7 | PTPN7 Entrez, Source | protein tyrosine phosphatase, non-receptor type 7 | 11047 | -0.110 | -0.0467 | No |
| 98 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 11550 | -0.131 | -0.0760 | No |
| 99 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 11710 | -0.139 | -0.0789 | No |
| 100 | HDGF | HDGF Entrez, Source | hepatoma-derived growth factor (high-mobility group protein 1-like) | 11910 | -0.150 | -0.0841 | No |
| 101 | IL23A | IL23A Entrez, Source | interleukin 23, alpha subunit p19 | 11932 | -0.152 | -0.0757 | No |
| 102 | ABCD4 | ABCD4 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 4 | 12076 | -0.163 | -0.0758 | No |
| 103 | PDZK1 | PDZK1 Entrez, Source | PDZ domain containing 1 | 12224 | -0.173 | -0.0756 | No |
| 104 | TACC2 | TACC2 Entrez, Source | transforming, acidic coiled-coil containing protein 2 | 12378 | -0.186 | -0.0749 | No |
| 105 | CD69 | CD69 Entrez, Source | CD69 molecule | 12507 | -0.200 | -0.0714 | No |
| 106 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 12664 | -0.219 | -0.0688 | No |
| 107 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 12747 | -0.232 | -0.0597 | No |
| 108 | GTF2A1 | GTF2A1 Entrez, Source | general transcription factor IIA, 1, 19/37kDa | 12822 | -0.246 | -0.0491 | No |
| 109 | VRK1 | VRK1 Entrez, Source | vaccinia related kinase 1 | 12925 | -0.271 | -0.0390 | No |
| 110 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 13108 | -0.331 | -0.0310 | No |
| 111 | ARNT | ARNT Entrez, Source | aryl hydrocarbon receptor nuclear translocator | 13157 | -0.367 | -0.0105 | No |
| 112 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 13164 | -0.372 | 0.0135 | No |
