Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$ARNT_01 |
| Enrichment Score (ES) | -0.39057022 |
| Normalized Enrichment Score (NES) | -1.4945585 |
| Nominal p-value | 0.014669927 |
| FDR q-value | 0.22736955 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 98 | 0.666 | 0.0443 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.0604 | No |
| 3 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 318 | 0.386 | 0.0891 | No |
| 4 | STX6 | STX6 Entrez, Source | syntaxin 6 | 766 | 0.222 | 0.0726 | No |
| 5 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.0763 | No |
| 6 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 970 | 0.186 | 0.0868 | No |
| 7 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 1087 | 0.172 | 0.0914 | No |
| 8 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1218 | 0.159 | 0.0939 | No |
| 9 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 1271 | 0.153 | 0.1019 | No |
| 10 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1319 | 0.149 | 0.1099 | No |
| 11 | TEF | TEF Entrez, Source | thyrotrophic embryonic factor | 1404 | 0.143 | 0.1147 | No |
| 12 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 1811 | 0.116 | 0.0930 | No |
| 13 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1870 | 0.113 | 0.0974 | No |
| 14 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1993 | 0.108 | 0.0966 | No |
| 15 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 2030 | 0.106 | 0.1022 | No |
| 16 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 2257 | 0.097 | 0.0926 | No |
| 17 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2385 | 0.092 | 0.0902 | No |
| 18 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2444 | 0.090 | 0.0928 | No |
| 19 | AP1GBP1 | AP1GBP1 Entrez, Source | AP1 gamma subunit binding protein 1 | 2473 | 0.089 | 0.0976 | No |
| 20 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 2507 | 0.088 | 0.1019 | No |
| 21 | CRY2 | CRY2 Entrez, Source | cryptochrome 2 (photolyase-like) | 2754 | 0.078 | 0.0894 | No |
| 22 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 2930 | 0.073 | 0.0819 | No |
| 23 | SLCO1C1 | SLCO1C1 Entrez, Source | solute carrier organic anion transporter family, member 1C1 | 2953 | 0.072 | 0.0858 | No |
| 24 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3101 | 0.068 | 0.0800 | No |
| 25 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 3556 | 0.056 | 0.0500 | No |
| 26 | PPP1R1B | PPP1R1B Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 1B (dopamine and cAMP regulated phosphoprotein, DARPP-32) | 3684 | 0.053 | 0.0445 | No |
| 27 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 3964 | 0.045 | 0.0270 | No |
| 28 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 4274 | 0.038 | 0.0066 | No |
| 29 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 4337 | 0.037 | 0.0048 | No |
| 30 | SNAP25 | SNAP25 Entrez, Source | synaptosomal-associated protein, 25kDa | 4406 | 0.036 | 0.0024 | No |
| 31 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 4510 | 0.034 | -0.0028 | No |
| 32 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 4986 | 0.024 | -0.0368 | No |
| 33 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4993 | 0.024 | -0.0354 | No |
| 34 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 5159 | 0.021 | -0.0462 | No |
| 35 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5213 | 0.020 | -0.0486 | No |
| 36 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5481 | 0.015 | -0.0676 | No |
| 37 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5509 | 0.014 | -0.0685 | No |
| 38 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 5526 | 0.014 | -0.0686 | No |
| 39 | ZFP91 | ZFP91 Entrez, Source | zinc finger protein 91 homolog (mouse) | 5690 | 0.011 | -0.0801 | No |
| 40 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5716 | 0.011 | -0.0811 | No |
| 41 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 5876 | 0.008 | -0.0926 | No |
| 42 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 6082 | 0.004 | -0.1078 | No |
| 43 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 6161 | 0.002 | -0.1135 | No |
| 44 | TBC1D15 | TBC1D15 Entrez, Source | TBC1 domain family, member 15 | 6194 | 0.001 | -0.1158 | No |
| 45 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1365 | No |
| 46 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 6540 | -0.004 | -0.1412 | No |
| 47 | TAC1 | TAC1 Entrez, Source | tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) | 6693 | -0.007 | -0.1522 | No |
| 48 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.1518 | No |
| 49 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 6743 | -0.008 | -0.1547 | No |
| 50 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 6749 | -0.008 | -0.1544 | No |
| 51 | SCYL1 | SCYL1 Entrez, Source | SCY1-like 1 (S. cerevisiae) | 7338 | -0.018 | -0.1974 | No |
| 52 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | -0.2251 | No |
| 53 | SLC39A11 | SLC39A11 Entrez, Source | solute carrier family 39 (metal ion transporter), member 11 | 7745 | -0.026 | -0.2240 | No |
| 54 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 7771 | -0.027 | -0.2238 | No |
| 55 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 7827 | -0.028 | -0.2258 | No |
| 56 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 7920 | -0.030 | -0.2304 | No |
| 57 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 7975 | -0.031 | -0.2321 | No |
| 58 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 8010 | -0.031 | -0.2323 | No |
| 59 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8085 | -0.033 | -0.2353 | No |
| 60 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 8092 | -0.033 | -0.2331 | No |
| 61 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 8295 | -0.037 | -0.2455 | No |
| 62 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 8308 | -0.038 | -0.2435 | No |
| 63 | CELSR3 | CELSR3 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) | 8453 | -0.040 | -0.2512 | No |
| 64 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 8462 | -0.041 | -0.2487 | No |
| 65 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 8733 | -0.046 | -0.2655 | No |
| 66 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 8841 | -0.049 | -0.2698 | No |
| 67 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 9017 | -0.052 | -0.2790 | No |
| 68 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 9213 | -0.056 | -0.2893 | No |
| 69 | RHEBL1 | RHEBL1 Entrez, Source | Ras homolog enriched in brain like 1 | 9295 | -0.058 | -0.2910 | No |
| 70 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 9339 | -0.059 | -0.2896 | No |
| 71 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9594 | -0.065 | -0.3037 | No |
| 72 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 9645 | -0.066 | -0.3024 | No |
| 73 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 10248 | -0.083 | -0.3414 | No |
| 74 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3431 | No |
| 75 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 10396 | -0.087 | -0.3390 | No |
| 76 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 10474 | -0.089 | -0.3379 | No |
| 77 | MTUS1 | MTUS1 Entrez, Source | mitochondrial tumor suppressor 1 | 10665 | -0.096 | -0.3448 | No |
| 78 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 10893 | -0.105 | -0.3538 | No |
| 79 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 11066 | -0.111 | -0.3582 | No |
| 80 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 11259 | -0.119 | -0.3635 | No |
| 81 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 11618 | -0.135 | -0.3801 | Yes |
| 82 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11646 | -0.136 | -0.3716 | Yes |
| 83 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11666 | -0.137 | -0.3625 | Yes |
| 84 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 11674 | -0.137 | -0.3524 | Yes |
| 85 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 11907 | -0.150 | -0.3582 | Yes |
| 86 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 11929 | -0.152 | -0.3480 | Yes |
| 87 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 12002 | -0.158 | -0.3412 | Yes |
| 88 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.3321 | Yes |
| 89 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 12068 | -0.162 | -0.3210 | Yes |
| 90 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3206 | Yes |
| 91 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.3080 | Yes |
| 92 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12263 | -0.177 | -0.2945 | Yes |
| 93 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2860 | Yes |
| 94 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 12353 | -0.184 | -0.2727 | Yes |
| 95 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12583 | -0.209 | -0.2738 | Yes |
| 96 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 12680 | -0.221 | -0.2639 | Yes |
| 97 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 12721 | -0.227 | -0.2492 | Yes |
| 98 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2353 | Yes |
| 99 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.2191 | Yes |
| 100 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12936 | -0.273 | -0.2064 | Yes |
| 101 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.1853 | Yes |
| 102 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.1643 | Yes |
| 103 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 12959 | -0.279 | -0.1436 | Yes |
| 104 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13002 | -0.293 | -0.1240 | Yes |
| 105 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13050 | -0.307 | -0.1037 | Yes |
| 106 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.0812 | Yes |
| 107 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 13111 | -0.334 | -0.0576 | Yes |
| 108 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 13233 | -0.442 | -0.0324 | Yes |
| 109 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13269 | -0.522 | 0.0055 | Yes |
