Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$ARNT_02 |
| Enrichment Score (ES) | -0.37324435 |
| Normalized Enrichment Score (NES) | -1.4436618 |
| Nominal p-value | 0.020618556 |
| FDR q-value | 0.25706398 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 84 | 0.686 | 0.0405 | No |
| 2 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 98 | 0.666 | 0.0851 | No |
| 3 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 191 | 0.498 | 0.1122 | No |
| 4 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.1315 | No |
| 5 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 363 | 0.357 | 0.1513 | No |
| 6 | STX6 | STX6 Entrez, Source | syntaxin 6 | 766 | 0.222 | 0.1361 | No |
| 7 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 830 | 0.208 | 0.1455 | No |
| 8 | AVPI1 | AVPI1 Entrez, Source | arginine vasopressin-induced 1 | 894 | 0.196 | 0.1542 | No |
| 9 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 926 | 0.191 | 0.1649 | No |
| 10 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1133 | 0.167 | 0.1608 | No |
| 11 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 1181 | 0.163 | 0.1683 | No |
| 12 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1218 | 0.159 | 0.1765 | No |
| 13 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 1479 | 0.137 | 0.1662 | No |
| 14 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 1866 | 0.113 | 0.1448 | No |
| 15 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 2257 | 0.097 | 0.1219 | No |
| 16 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2385 | 0.092 | 0.1187 | No |
| 17 | SNN | SNN Entrez, Source | stannin | 2406 | 0.092 | 0.1234 | No |
| 18 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 2423 | 0.091 | 0.1284 | No |
| 19 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2444 | 0.090 | 0.1330 | No |
| 20 | SLCO1C1 | SLCO1C1 Entrez, Source | solute carrier organic anion transporter family, member 1C1 | 2953 | 0.072 | 0.0996 | No |
| 21 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3101 | 0.068 | 0.0932 | No |
| 22 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 3234 | 0.064 | 0.0876 | No |
| 23 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3280 | 0.063 | 0.0885 | No |
| 24 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 3403 | 0.060 | 0.0834 | No |
| 25 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 3675 | 0.053 | 0.0666 | No |
| 26 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 3715 | 0.052 | 0.0671 | No |
| 27 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 3779 | 0.051 | 0.0658 | No |
| 28 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 3964 | 0.045 | 0.0550 | No |
| 29 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 4050 | 0.043 | 0.0516 | No |
| 30 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 4337 | 0.037 | 0.0325 | No |
| 31 | SEC23IP | SEC23IP Entrez, Source | SEC23 interacting protein | 4430 | 0.035 | 0.0279 | No |
| 32 | GNAS | GNAS Entrez, Source | GNAS complex locus | 4431 | 0.035 | 0.0303 | No |
| 33 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 4434 | 0.035 | 0.0326 | No |
| 34 | ATP6V1H | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 4889 | 0.026 | 0.0001 | No |
| 35 | RRAGB | RRAGB Entrez, Source | Ras-related GTP binding B | 4983 | 0.024 | -0.0053 | No |
| 36 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4993 | 0.024 | -0.0043 | No |
| 37 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 5159 | 0.021 | -0.0153 | No |
| 38 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5193 | 0.020 | -0.0164 | No |
| 39 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5509 | 0.014 | -0.0393 | No |
| 40 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 5526 | 0.014 | -0.0395 | No |
| 41 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 5801 | 0.009 | -0.0596 | No |
| 42 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 5876 | 0.008 | -0.0647 | No |
| 43 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 5975 | 0.006 | -0.0717 | No |
| 44 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 6092 | 0.003 | -0.0802 | No |
| 45 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 6295 | -0.000 | -0.0955 | No |
| 46 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.1017 | No |
| 47 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1083 | No |
| 48 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6502 | -0.004 | -0.1103 | No |
| 49 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 6743 | -0.008 | -0.1279 | No |
| 50 | HRH3 | HRH3 Entrez, Source | histamine receptor H3 | 6821 | -0.009 | -0.1331 | No |
| 51 | ZIC1 | ZIC1 Entrez, Source | Zic family member 1 (odd-paired homolog, Drosophila) | 6837 | -0.009 | -0.1336 | No |
| 52 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 7067 | -0.014 | -0.1500 | No |
| 53 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 7459 | -0.021 | -0.1781 | No |
| 54 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 7498 | -0.022 | -0.1795 | No |
| 55 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 7603 | -0.024 | -0.1858 | No |
| 56 | CLTC | CLTC Entrez, Source | clathrin, heavy chain (Hc) | 7654 | -0.025 | -0.1878 | No |
| 57 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 8010 | -0.031 | -0.2125 | No |
| 58 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 8060 | -0.032 | -0.2140 | No |
| 59 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 8081 | -0.033 | -0.2133 | No |
| 60 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8212 | -0.035 | -0.2207 | No |
| 61 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 8308 | -0.038 | -0.2253 | No |
| 62 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 8462 | -0.041 | -0.2340 | No |
| 63 | GGN | GGN Entrez, Source | gametogenetin | 8728 | -0.046 | -0.2509 | No |
| 64 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 9017 | -0.052 | -0.2691 | No |
| 65 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9112 | -0.054 | -0.2725 | No |
| 66 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 9204 | -0.056 | -0.2756 | No |
| 67 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 9213 | -0.056 | -0.2723 | No |
| 68 | CANX | CANX Entrez, Source | calnexin | 9223 | -0.057 | -0.2691 | No |
| 69 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9465 | -0.062 | -0.2831 | No |
| 70 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9506 | -0.063 | -0.2818 | No |
| 71 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10112 | -0.079 | -0.3221 | No |
| 72 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 10248 | -0.083 | -0.3267 | No |
| 73 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 10468 | -0.089 | -0.3371 | No |
| 74 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 10474 | -0.089 | -0.3314 | No |
| 75 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10485 | -0.090 | -0.3260 | No |
| 76 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10984 | -0.108 | -0.3562 | No |
| 77 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 11210 | -0.116 | -0.3653 | Yes |
| 78 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 11259 | -0.119 | -0.3608 | Yes |
| 79 | SPG21 | SPG21 Entrez, Source | spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome) | 11285 | -0.120 | -0.3545 | Yes |
| 80 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 11398 | -0.125 | -0.3544 | Yes |
| 81 | RAB24 | RAB24 Entrez, Source | RAB24, member RAS oncogene family | 11518 | -0.130 | -0.3545 | Yes |
| 82 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 11674 | -0.137 | -0.3569 | Yes |
| 83 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 11814 | -0.145 | -0.3575 | Yes |
| 84 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 11829 | -0.146 | -0.3485 | Yes |
| 85 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 11907 | -0.150 | -0.3440 | Yes |
| 86 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 11929 | -0.152 | -0.3353 | Yes |
| 87 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 12007 | -0.158 | -0.3303 | Yes |
| 88 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 12176 | -0.170 | -0.3314 | Yes |
| 89 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3245 | Yes |
| 90 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 12345 | -0.183 | -0.3195 | Yes |
| 91 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 12353 | -0.184 | -0.3074 | Yes |
| 92 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12583 | -0.209 | -0.3105 | Yes |
| 93 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12748 | -0.232 | -0.3070 | Yes |
| 94 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 12770 | -0.237 | -0.2924 | Yes |
| 95 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12773 | -0.237 | -0.2763 | Yes |
| 96 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2607 | Yes |
| 97 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.2468 | Yes |
| 98 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2318 | Yes |
| 99 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12882 | -0.262 | -0.2157 | Yes |
| 100 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12936 | -0.273 | -0.2011 | Yes |
| 101 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 12959 | -0.279 | -0.1837 | Yes |
| 102 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.1651 | Yes |
| 103 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13002 | -0.293 | -0.1474 | Yes |
| 104 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13030 | -0.302 | -0.1288 | Yes |
| 105 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13050 | -0.307 | -0.1092 | Yes |
| 106 | PRSS15 | PRSS15 Entrez, Source | protease, serine, 15 | 13072 | -0.315 | -0.0892 | Yes |
| 107 | CUL5 | CUL5 Entrez, Source | cullin 5 | 13074 | -0.316 | -0.0677 | Yes |
| 108 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.0464 | Yes |
| 109 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 13233 | -0.442 | -0.0276 | Yes |
| 110 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 13271 | -0.523 | 0.0054 | Yes |
