Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetV$ATF4_Q2
Enrichment Score (ES)0.4792546
Normalized Enrichment Score (NES)1.7514621
Nominal p-value0.0
FDR q-value0.03979663
FWER p-Value0.995
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$ATF4_Q2   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog31.6220.0973Yes
2LAMC2LAMC2
Entrez,  Source
laminin, gamma 2231.0210.1572Yes
3MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)310.9350.2128Yes
4PAHPAH
Entrez,  Source
phenylalanine hydroxylase1330.5970.2411Yes
5SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase1910.4980.2667Yes
6USP2USP2
Entrez,  Source
ubiquitin specific peptidase 22070.4800.2944Yes
7MYBPHMYBPH
Entrez,  Source
myosin binding protein H2590.4310.3164Yes
8HS3ST2HS3ST2
Entrez,  Source
heparan sulfate (glucosamine) 3-O-sulfotransferase 23080.3940.3364Yes
9JAG1JAG1
Entrez,  Source
jagged 1 (Alagille syndrome)3180.3860.3590Yes
10KCNN2KCNN2
Entrez,  Source
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 24030.3360.3728Yes
11HCSTHCST
Entrez,  Source
hematopoietic cell signal transducer5170.2800.3811Yes
12PKIAPKIA
Entrez,  Source
protein kinase (cAMP-dependent, catalytic) inhibitor alpha5880.2600.3914Yes
13SLC38A2SLC38A2
Entrez,  Source
solute carrier family 38, member 26310.2490.4032Yes
14PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)6430.2470.4172Yes
15CXCL16CXCL16
Entrez,  Source
chemokine (C-X-C motif) ligand 167340.2290.4241Yes
16ICA1ICA1
Entrez,  Source
islet cell autoantigen 1, 69kDa7530.2260.4363Yes
17LMO4LMO4
Entrez,  Source
LIM domain only 48240.2090.4436Yes
18RAB7RAB7
Entrez,  Source
RAB7, member RAS oncogene family8910.1970.4504Yes
19DIRC2DIRC2
Entrez,  Source
disrupted in renal carcinoma 29260.1910.4593Yes
20PRICKLE1PRICKLE1
Entrez,  Source
prickle homolog 1 (Drosophila)9270.1910.4708Yes
21PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 210470.1770.4724Yes
22DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112660.1540.4652Yes
23PPP2R5BPPP2R5B
Entrez,  Source
protein phosphatase 2, regulatory subunit B (B56), beta isoform14970.1350.4559Yes
24GRM3GRM3
Entrez,  Source
glutamate receptor, metabotropic 315230.1330.4620Yes
25ZFYVE27ZFYVE27
Entrez,  Source
zinc finger, FYVE domain containing 2715730.1300.4661Yes
26DCTN1DCTN1
Entrez,  Source
dynactin 1 (p150, glued homolog, Drosophila)15780.1300.4736Yes
27ARG2ARG2
Entrez,  Source
arginase, type II16060.1280.4793Yes
28MAOAMAOA
Entrez,  Source
monoamine oxidase A21590.1010.4436No
29LTBP1LTBP1
Entrez,  Source
latent transforming growth factor beta binding protein 122610.0970.4418No
30TPM4TPM4
Entrez,  Source
tropomyosin 422930.0960.4452No
31PLSCR3PLSCR3
Entrez,  Source
phospholipid scramblase 323480.0940.4467No
32ABCA2ABCA2
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 224630.0890.4434No
33EDG5EDG5
Entrez,  Source
endothelial differentiation, sphingolipid G-protein-coupled receptor, 524790.0890.4476No
34BRAFBRAF
Entrez,  Source
v-raf murine sarcoma viral oncogene homolog B126050.0830.4432No
35CX36CX36
Entrez,  Source
-26950.0800.4413No
36ECM1ECM1
Entrez,  Source
extracellular matrix protein 127180.0800.4444No
37PNRC1PNRC1
Entrez,  Source
proline-rich nuclear receptor coactivator 129150.0740.4340No
38CENTA1CENTA1
Entrez,  Source
centaurin, alpha 131670.0670.4190No
39ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein32860.0630.4139No
40F2RL2F2RL2
Entrez,  Source
coagulation factor II (thrombin) receptor-like 240020.0450.3624No
41ELOVL5ELOVL5
Entrez,  Source
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)40360.0440.3626No
42MAP1LC3AMAP1LC3A
Entrez,  Source
microtubule-associated protein 1 light chain 3 alpha40390.0440.3650No
43MESDC1MESDC1
Entrez,  Source
mesoderm development candidate 141190.0420.3616No
44MPP2MPP2
Entrez,  Source
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)42030.0390.3577No
45PEX12PEX12
Entrez,  Source
peroxisomal biogenesis factor 1242610.0380.3556No
46GNASGNAS
Entrez,  Source
GNAS complex locus44310.0350.3450No
47NR4A3NR4A3
Entrez,  Source
nuclear receptor subfamily 4, group A, member 347530.0290.3224No
48CLSTN3CLSTN3
Entrez,  Source
calsyntenin 349990.0240.3053No
49ALDOAALDOA
Entrez,  Source
aldolase A, fructose-bisphosphate50390.0230.3038No
50CAPN6CAPN6
Entrez,  Source
calpain 652470.0200.2893No
51CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)52650.0190.2892No
52NRXN2NRXN2
Entrez,  Source
neurexin 253410.0180.2846No
53PSDPSD
Entrez,  Source
pleckstrin and Sec7 domain containing55710.0130.2680No
54USP48USP48
Entrez,  Source
ubiquitin specific peptidase 4856000.0130.2667No
55SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase56500.0120.2637No
56FOXD3FOXD3
Entrez,  Source
forkhead box D358760.0080.2471No
57PDE4DPDE4D
Entrez,  Source
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)58900.0070.2466No
58USP14USP14
Entrez,  Source
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)59280.0070.2442No
59KCNJ2KCNJ2
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 260480.0040.2354No
60NUP98NUP98
Entrez,  Source
nucleoporin 98kDa62680.0000.2189No
61MRGPRFMRGPRF
Entrez,  Source
MAS-related GPR, member F6355-0.0010.2124No
62CDC5LCDC5L
Entrez,  Source
CDC5 cell division cycle 5-like (S. pombe)6411-0.0020.2084No
63BSNBSN
Entrez,  Source
bassoon (presynaptic cytomatrix protein)6585-0.0050.1956No
64CBX3CBX3
Entrez,  Source
chromobox homolog 3 (HP1 gamma homolog, Drosophila)6679-0.0070.1890No
65RNF44RNF44
Entrez,  Source
ring finger protein 446743-0.0080.1847No
66SCAMP5SCAMP5
Entrez,  Source
secretory carrier membrane protein 56796-0.0090.1813No
67PAX3PAX3
Entrez,  Source
paired box gene 3 (Waardenburg syndrome 1)6824-0.0090.1798No
68IKBKBIKBKB
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta6828-0.0090.1801No
69SMARCB1SMARCB1
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 17003-0.0120.1677No
70MAP3K7IP2MAP3K7IP2
Entrez,  Source
mitogen-activated protein kinase kinase kinase 7 interacting protein 27170-0.0150.1560No
71TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa7434-0.0200.1373No
72CDK5R1CDK5R1
Entrez,  Source
cyclin-dependent kinase 5, regulatory subunit 1 (p35)7459-0.0210.1368No
73AP2M1AP2M1
Entrez,  Source
adaptor-related protein complex 2, mu 1 subunit7464-0.0210.1377No
74SMAD1SMAD1
Entrez,  Source
SMAD, mothers against DPP homolog 1 (Drosophila)7536-0.0220.1337No
75TRIB1TRIB1
Entrez,  Source
tribbles homolog 1 (Drosophila)7632-0.0240.1280No
76GABRA1GABRA1
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 17649-0.0250.1282No
77PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 127923-0.0300.1093No
78FLNCFLNC
Entrez,  Source
filamin C, gamma (actin binding protein 280)7939-0.0300.1100No
79GPM6BGPM6B
Entrez,  Source
glycoprotein M6B8060-0.0320.1029No
80PTPRUPTPRU
Entrez,  Source
protein tyrosine phosphatase, receptor type, U8180-0.0350.0960No
81HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa8212-0.0350.0958No
82GNL1GNL1
Entrez,  Source
guanine nucleotide binding protein-like 18250-0.0360.0951No
83FGF14FGF14
Entrez,  Source
fibroblast growth factor 148295-0.0370.0941No
84PAK3PAK3
Entrez,  Source
p21 (CDKN1A)-activated kinase 38370-0.0390.0908No
85CTCFCTCF
Entrez,  Source
CCCTC-binding factor (zinc finger protein)8374-0.0390.0929No
86TITF1TITF1
Entrez,  Source
thyroid transcription factor 18658-0.0450.0742No
87HOXC10HOXC10
Entrez,  Source
homeobox C108695-0.0450.0742No
88ITM2BITM2B
Entrez,  Source
integral membrane protein 2B8720-0.0460.0751No
89GGNGGN
Entrez,  Source
gametogenetin8728-0.0460.0773No
90SYT2SYT2
Entrez,  Source
synaptotagmin II9102-0.0540.0524No
91AHRAHR
Entrez,  Source
aryl hydrocarbon receptor9118-0.0540.0545No
92AHI1AHI1
Entrez,  Source
Abelson helper integration site 19218-0.0560.0504No
93SULT4A1SULT4A1
Entrez,  Source
sulfotransferase family 4A, member 19281-0.0580.0492No
94LEPROTL1LEPROTL1
Entrez,  Source
leptin receptor overlapping transcript-like 19362-0.0600.0467No
95ITPKCITPKC
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase C9405-0.0610.0472No
96DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked9594-0.0650.0369No
97GPR56GPR56
Entrez,  Source
G protein-coupled receptor 569622-0.0660.0388No
98SLC18A2SLC18A2
Entrez,  Source
solute carrier family 18 (vesicular monoamine), member 29786-0.0700.0307No
99PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 49912-0.0740.0257No
100NDRG2NDRG2
Entrez,  Source
NDRG family member 29944-0.0750.0278No
101ROM1ROM1
Entrez,  Source
retinal outer segment membrane protein 19956-0.0750.0315No
102MRRFMRRF
Entrez,  Source
mitochondrial ribosome recycling factor10343-0.0860.0074No
103PABPC1PABPC1
Entrez,  Source
poly(A) binding protein, cytoplasmic 110349-0.0860.0122No
104ATF1ATF1
Entrez,  Source
activating transcription factor 110381-0.0870.0151No
105HNRPABHNRPAB
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A/B10402-0.0870.0188No
106NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)10565-0.0920.0121No
107PRR3PRR3
Entrez,  Source
proline rich 310589-0.0930.0160No
108PDAP1PDAP1
Entrez,  Source
PDGFA associated protein 110592-0.0930.0214No
109PSMD4PSMD4
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 410681-0.0960.0206No
110PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit10702-0.0970.0249No
111HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed10765-0.0990.0262No
112PPP1R10PPP1R10
Entrez,  Source
protein phosphatase 1, regulatory subunit 1010924-0.1060.0206No
113CIRBPCIRBP
Entrez,  Source
cold inducible RNA binding protein10982-0.1080.0227No
114EIF4G1EIF4G1
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 110984-0.1080.0291No
115TRIM39TRIM39
Entrez,  Source
tripartite motif-containing 3911239-0.1170.0169No
116ADCK4ADCK4
Entrez,  Source
aarF domain containing kinase 411243-0.1180.0238No
117CDH23CDH23
Entrez,  Source
cadherin-like 2311301-0.1200.0267No
118TDGTDG
Entrez,  Source
thymine-DNA glycosylase11393-0.1240.0273No
119MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B11505-0.1290.0267No
120BMFBMF
Entrez,  Source
Bcl2 modifying factor11710-0.1390.0196No
121PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa11805-0.1450.0212No
122MSX2MSX2
Entrez,  Source
msh homeobox homolog 2 (Drosophila)11856-0.1470.0262No
123GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta11989-0.1560.0256No
124NR4A2NR4A2
Entrez,  Source
nuclear receptor subfamily 4, group A, member 212585-0.209-0.0068No
125SV2BSV2B
Entrez,  Source
synaptic vesicle glycoprotein 2B12618-0.2130.0036No
126GTF2A1GTF2A1
Entrez,  Source
general transcription factor IIA, 1, 19/37kDa12822-0.2460.0030No
127HN1HN1
Entrez,  Source
hematological and neurological expressed 112908-0.2690.0127No
128XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)13111-0.3340.0175No
Table: GSEA details [plain text format]



Fig 2: V$ATF4_Q2   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$ATF4_Q2: Random ES distribution   
Gene set null distribution of ES for V$ATF4_Q2