Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | V$CDC5_01 |
| Enrichment Score (ES) | 0.47190538 |
| Normalized Enrichment Score (NES) | 1.7189028 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04935406 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 18 | 1.071 | 0.0720 | Yes |
| 2 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 27 | 0.963 | 0.1373 | Yes |
| 3 | RGS1 | RGS1 Entrez, Source | regulator of G-protein signalling 1 | 73 | 0.715 | 0.1828 | Yes |
| 4 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 118 | 0.623 | 0.2221 | Yes |
| 5 | SLCO2A1 | SLCO2A1 Entrez, Source | solute carrier organic anion transporter family, member 2A1 | 230 | 0.459 | 0.2451 | Yes |
| 6 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 255 | 0.437 | 0.2732 | Yes |
| 7 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 312 | 0.390 | 0.2957 | Yes |
| 8 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 342 | 0.369 | 0.3187 | Yes |
| 9 | SLC6A13 | SLC6A13 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, GABA), member 13 | 459 | 0.302 | 0.3306 | Yes |
| 10 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 718 | 0.232 | 0.3269 | Yes |
| 11 | PDGFA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 729 | 0.230 | 0.3419 | Yes |
| 12 | GPC3 | GPC3 Entrez, Source | glypican 3 | 757 | 0.224 | 0.3552 | Yes |
| 13 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 793 | 0.215 | 0.3673 | Yes |
| 14 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 799 | 0.213 | 0.3815 | Yes |
| 15 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 807 | 0.212 | 0.3955 | Yes |
| 16 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 833 | 0.207 | 0.4078 | Yes |
| 17 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 932 | 0.190 | 0.4134 | Yes |
| 18 | GFRA1 | GFRA1 Entrez, Source | GDNF family receptor alpha 1 | 947 | 0.188 | 0.4252 | Yes |
| 19 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1066 | 0.174 | 0.4283 | Yes |
| 20 | DGKB | DGKB Entrez, Source | diacylglycerol kinase, beta 90kDa | 1074 | 0.174 | 0.4396 | Yes |
| 21 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 1115 | 0.169 | 0.4482 | Yes |
| 22 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 1221 | 0.159 | 0.4511 | Yes |
| 23 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 1302 | 0.150 | 0.4553 | Yes |
| 24 | FGF12 | FGF12 Entrez, Source | fibroblast growth factor 12 | 1334 | 0.148 | 0.4632 | Yes |
| 25 | POU3F1 | POU3F1 Entrez, Source | POU domain, class 3, transcription factor 1 | 1352 | 0.147 | 0.4719 | Yes |
| 26 | PROK2 | PROK2 Entrez, Source | prokineticin 2 | 1757 | 0.119 | 0.4495 | No |
| 27 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 1797 | 0.117 | 0.4546 | No |
| 28 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 1801 | 0.117 | 0.4623 | No |
| 29 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 2402 | 0.092 | 0.4233 | No |
| 30 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 2451 | 0.090 | 0.4258 | No |
| 31 | SAMSN1 | SAMSN1 Entrez, Source | SAM domain, SH3 domain and nuclear localisation signals, 1 | 2606 | 0.083 | 0.4198 | No |
| 32 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 2623 | 0.083 | 0.4243 | No |
| 33 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2696 | 0.080 | 0.4244 | No |
| 34 | SLC12A8 | SLC12A8 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 8 | 2697 | 0.080 | 0.4299 | No |
| 35 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 2744 | 0.079 | 0.4318 | No |
| 36 | FGF10 | FGF10 Entrez, Source | fibroblast growth factor 10 | 2765 | 0.078 | 0.4356 | No |
| 37 | MBNL1 | MBNL1 Entrez, Source | muscleblind-like (Drosophila) | 2930 | 0.073 | 0.4282 | No |
| 38 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 2952 | 0.072 | 0.4316 | No |
| 39 | OSR2 | OSR2 Entrez, Source | odd-skipped related 2 (Drosophila) | 3029 | 0.070 | 0.4306 | No |
| 40 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 3037 | 0.070 | 0.4349 | No |
| 41 | CART1 | CART1 Entrez, Source | cartilage paired-class homeoprotein 1 | 3328 | 0.062 | 0.4172 | No |
| 42 | NOVA1 | NOVA1 Entrez, Source | neuro-oncological ventral antigen 1 | 3664 | 0.053 | 0.3955 | No |
| 43 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 3698 | 0.052 | 0.3966 | No |
| 44 | SLC27A4 | SLC27A4 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 4 | 4026 | 0.044 | 0.3749 | No |
| 45 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 4035 | 0.044 | 0.3773 | No |
| 46 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 4113 | 0.042 | 0.3743 | No |
| 47 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 4345 | 0.037 | 0.3594 | No |
| 48 | ESRRG | ESRRG Entrez, Source | estrogen-related receptor gamma | 4402 | 0.036 | 0.3576 | No |
| 49 | PBX2 | PBX2 Entrez, Source | pre-B-cell leukemia transcription factor 2 | 4426 | 0.035 | 0.3583 | No |
| 50 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 4548 | 0.033 | 0.3514 | No |
| 51 | SYT4 | SYT4 Entrez, Source | synaptotagmin IV | 4603 | 0.032 | 0.3495 | No |
| 52 | BIRC4 | BIRC4 Entrez, Source | baculoviral IAP repeat-containing 4 | 4947 | 0.025 | 0.3253 | No |
| 53 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 5081 | 0.023 | 0.3168 | No |
| 54 | SCN7A | SCN7A Entrez, Source | sodium channel, voltage-gated, type VII, alpha | 5325 | 0.018 | 0.2997 | No |
| 55 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 5378 | 0.017 | 0.2969 | No |
| 56 | COL16A1 | COL16A1 Entrez, Source | collagen, type XVI, alpha 1 | 5388 | 0.017 | 0.2974 | No |
| 57 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 5523 | 0.014 | 0.2882 | No |
| 58 | ODF1 | ODF1 Entrez, Source | outer dense fiber of sperm tails 1 | 5623 | 0.012 | 0.2816 | No |
| 59 | PLCB3 | PLCB3 Entrez, Source | phospholipase C, beta 3 (phosphatidylinositol-specific) | 5675 | 0.011 | 0.2785 | No |
| 60 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 5770 | 0.010 | 0.2721 | No |
| 61 | TNNI3K | TNNI3K Entrez, Source | TNNI3 interacting kinase | 5803 | 0.009 | 0.2703 | No |
| 62 | MUSK | MUSK Entrez, Source | muscle, skeletal, receptor tyrosine kinase | 5921 | 0.007 | 0.2619 | No |
| 63 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 6077 | 0.004 | 0.2504 | No |
| 64 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 6299 | -0.000 | 0.2337 | No |
| 65 | UNC13D | UNC13D Entrez, Source | unc-13 homolog D (C. elegans) | 6398 | -0.002 | 0.2264 | No |
| 66 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 6476 | -0.003 | 0.2208 | No |
| 67 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 6502 | -0.004 | 0.2192 | No |
| 68 | PRRX1 | PRRX1 Entrez, Source | paired related homeobox 1 | 6636 | -0.006 | 0.2096 | No |
| 69 | PPP2R2B | PPP2R2B Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 6664 | -0.007 | 0.2080 | No |
| 70 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 6716 | -0.007 | 0.2046 | No |
| 71 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 6918 | -0.011 | 0.1902 | No |
| 72 | CHRDL1 | CHRDL1 Entrez, Source | chordin-like 1 | 7218 | -0.016 | 0.1687 | No |
| 73 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 7255 | -0.017 | 0.1671 | No |
| 74 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7323 | -0.018 | 0.1633 | No |
| 75 | TCF21 | TCF21 Entrez, Source | transcription factor 21 | 7391 | -0.020 | 0.1596 | No |
| 76 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 7645 | -0.024 | 0.1421 | No |
| 77 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 7811 | -0.028 | 0.1316 | No |
| 78 | CHRNA5 | CHRNA5 Entrez, Source | cholinergic receptor, nicotinic, alpha 5 | 7949 | -0.030 | 0.1233 | No |
| 79 | CSNK1G3 | CSNK1G3 Entrez, Source | casein kinase 1, gamma 3 | 8073 | -0.033 | 0.1162 | No |
| 80 | GPR85 | GPR85 Entrez, Source | G protein-coupled receptor 85 | 8109 | -0.034 | 0.1159 | No |
| 81 | SHH | SHH Entrez, Source | sonic hedgehog homolog (Drosophila) | 8114 | -0.034 | 0.1179 | No |
| 82 | FUT11 | FUT11 Entrez, Source | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 8544 | -0.042 | 0.0884 | No |
| 83 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 8595 | -0.043 | 0.0875 | No |
| 84 | TITF1 | TITF1 Entrez, Source | thyroid transcription factor 1 | 8658 | -0.045 | 0.0859 | No |
| 85 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 8942 | -0.051 | 0.0680 | No |
| 86 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 9217 | -0.056 | 0.0511 | No |
| 87 | KCNK12 | KCNK12 Entrez, Source | potassium channel, subfamily K, member 12 | 9386 | -0.060 | 0.0425 | No |
| 88 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 9390 | -0.060 | 0.0464 | No |
| 89 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 9402 | -0.061 | 0.0498 | No |
| 90 | PCDH8 | PCDH8 Entrez, Source | protocadherin 8 | 9427 | -0.061 | 0.0521 | No |
| 91 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 10068 | -0.079 | 0.0091 | No |
| 92 | ARPC5L | ARPC5L Entrez, Source | actin related protein 2/3 complex, subunit 5-like | 10169 | -0.081 | 0.0071 | No |
| 93 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 10258 | -0.083 | 0.0061 | No |
| 94 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 10344 | -0.086 | 0.0056 | No |
| 95 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 10664 | -0.096 | -0.0120 | No |
| 96 | ACTR10 | ACTR10 Entrez, Source | actin-related protein 10 homolog (S. cerevisiae) | 10732 | -0.098 | -0.0103 | No |
| 97 | LIN7A | LIN7A Entrez, Source | lin-7 homolog A (C. elegans) | 10847 | -0.103 | -0.0119 | No |
| 98 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 10986 | -0.108 | -0.0150 | No |
| 99 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 11304 | -0.121 | -0.0307 | No |
| 100 | ROD1 | ROD1 Entrez, Source | ROD1 regulator of differentiation 1 (S. pombe) | 11981 | -0.156 | -0.0711 | No |
| 101 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.0621 | No |
| 102 | BMPR2 | BMPR2 Entrez, Source | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 12122 | -0.166 | -0.0594 | No |
| 103 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 12159 | -0.169 | -0.0506 | No |
| 104 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 12209 | -0.172 | -0.0425 | No |
| 105 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 12221 | -0.173 | -0.0315 | No |
| 106 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.0279 | No |
| 107 | FNBP1 | FNBP1 Entrez, Source | formin binding protein 1 | 12404 | -0.188 | -0.0198 | No |
| 108 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 12438 | -0.192 | -0.0092 | No |
| 109 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 12445 | -0.193 | 0.0036 | No |
| 110 | LMNA | LMNA Entrez, Source | lamin A/C | 12500 | -0.199 | 0.0131 | No |
| 111 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 12653 | -0.218 | 0.0165 | No |
| 112 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12748 | -0.232 | 0.0253 | No |
| 113 | NDNL2 | NDNL2 Entrez, Source | necdin-like 2 | 12975 | -0.285 | 0.0277 | No |
