Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetV$DR4_Q2
Enrichment Score (ES)0.48413777
Normalized Enrichment Score (NES)1.7189989
Nominal p-value0.0
FDR q-value0.049597975
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: V$DR4_Q2   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 2121.2540.1081Yes
2ARHGAP24ARHGAP24
Entrez,  Source
Rho GTPase activating protein 24440.8380.1787Yes
3ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle600.7620.2438Yes
4ABCG1ABCG1
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 11790.5190.2800Yes
5SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase1910.4980.3224Yes
6PTK2BPTK2B
Entrez,  Source
PTK2B protein tyrosine kinase 2 beta2240.4630.3603Yes
7IHPK2IHPK2
Entrez,  Source
inositol hexaphosphate kinase 23130.3880.3874Yes
8NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha5650.2650.3914Yes
9EDN1EDN1
Entrez,  Source
endothelin 16480.2450.4066Yes
10CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 17960.2150.4141Yes
11FOXP1FOXP1
Entrez,  Source
forkhead box P18330.2070.4294Yes
12ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide9730.1860.4351Yes
13OPTNOPTN
Entrez,  Source
optineurin9970.1830.4493Yes
14PLAG1PLAG1
Entrez,  Source
pleiomorphic adenoma gene 111150.1690.4551Yes
15ABCA1ABCA1
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 113190.1490.4527Yes
16RASL11BRASL11B
Entrez,  Source
RAS-like, family 11, member B13640.1460.4621Yes
17TNFRSF12ATNFRSF12A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 12A13740.1450.4740Yes
18TGOLN2TGOLN2
Entrez,  Source
trans-golgi network protein 214340.1400.4817Yes
19NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)15540.1310.4841Yes
20LRP3LRP3
Entrez,  Source
low density lipoprotein receptor-related protein 318220.1160.4741No
21ENO2ENO2
Entrez,  Source
enolase 2 (gamma, neuronal)18890.1120.4788No
22ACSL3ACSL3
Entrez,  Source
acyl-CoA synthetase long-chain family member 321160.1030.4707No
23HMGB1HMGB1
Entrez,  Source
high-mobility group box 123370.0940.4623No
24NRG1NRG1
Entrez,  Source
neuregulin 123470.0940.4697No
25OBSCNOBSCN
Entrez,  Source
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF25760.0840.4598No
26APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 226570.0820.4609No
27CX36CX36
Entrez,  Source
-26950.0800.4651No
28ACACAACACA
Entrez,  Source
acetyl-Coenzyme A carboxylase alpha29480.0730.4524No
29ACCN3ACCN3
Entrez,  Source
amiloride-sensitive cation channel 331750.0660.4411No
30SNIPSNIP
Entrez,  Source
-33010.0630.4371No
31COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 433200.0620.4411No
32MYH13MYH13
Entrez,  Source
myosin, heavy chain 13, skeletal muscle33830.0610.4417No
33NR5A2NR5A2
Entrez,  Source
nuclear receptor subfamily 5, group A, member 235280.0570.4358No
34SLC7A9SLC7A9
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 935590.0560.4383No
35NOVA1NOVA1
Entrez,  Source
neuro-oncological ventral antigen 136640.0530.4351No
36GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)37490.0510.4332No
37TEAD3TEAD3
Entrez,  Source
TEA domain family member 338390.0490.4308No
38ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)40050.0440.4222No
39ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)40110.0440.4256No
40APOC1APOC1
Entrez,  Source
apolipoprotein C-I40220.0440.4287No
41MAP1LC3AMAP1LC3A
Entrez,  Source
microtubule-associated protein 1 light chain 3 alpha40390.0440.4313No
42NPEPPSNPEPPS
Entrez,  Source
aminopeptidase puromycin sensitive40430.0440.4348No
43TGFB3TGFB3
Entrez,  Source
transforming growth factor, beta 341130.0420.4333No
44NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)47670.0290.3864No
45ATP1A2ATP1A2
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide49430.0250.3754No
46GGPS1GGPS1
Entrez,  Source
geranylgeranyl diphosphate synthase 151080.0220.3649No
47DLX1DLX1
Entrez,  Source
distal-less homeobox 152430.0200.3565No
48AMHR2AMHR2
Entrez,  Source
anti-Mullerian hormone receptor, type II54080.0170.3456No
49NLGN3NLGN3
Entrez,  Source
neuroligin 354670.0160.3425No
50NEUROG1NEUROG1
Entrez,  Source
neurogenin 154880.0150.3423No
51PPARDPPARD
Entrez,  Source
peroxisome proliferative activated receptor, delta55320.0140.3403No
52ATP5G1ATP5G1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)56040.0130.3361No
53SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase56500.0120.3337No
54GNB2GNB2
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 258010.0090.3231No
55ADD3ADD3
Entrez,  Source
adducin 3 (gamma)58200.0090.3225No
56FOXD3FOXD3
Entrez,  Source
forkhead box D358760.0080.3190No
57RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)58920.0070.3185No
58UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I59270.0070.3165No
59FGF11FGF11
Entrez,  Source
fibroblast growth factor 1159650.0060.3143No
60PEX11BPEX11B
Entrez,  Source
peroxisomal biogenesis factor 11B59880.0050.3131No
61CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 259970.0050.3129No
62DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)61860.0010.2988No
63NELL2NELL2
Entrez,  Source
NEL-like 2 (chicken)6480-0.0030.2770No
64MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)6716-0.0070.2599No
65NNATNNAT
Entrez,  Source
neuronatin6767-0.0080.2568No
66HRH3HRH3
Entrez,  Source
histamine receptor H36821-0.0090.2536No
67ACY1ACY1
Entrez,  Source
aminoacylase 16868-0.0100.2510No
68SEMA6CSEMA6C
Entrez,  Source
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C6955-0.0110.2455No
69NXPH4NXPH4
Entrez,  Source
neurexophilin 47004-0.0120.2430No
70GARTGART
Entrez,  Source
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase7019-0.0130.2430No
71CRABP2CRABP2
Entrez,  Source
cellular retinoic acid binding protein 27366-0.0190.2185No
72GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor7663-0.0250.1983No
73SCAMP3SCAMP3
Entrez,  Source
secretory carrier membrane protein 37665-0.0250.2004No
74PCSK1NPCSK1N
Entrez,  Source
proprotein convertase subtilisin/kexin type 1 inhibitor7755-0.0260.1960No
75KCND3KCND3
Entrez,  Source
potassium voltage-gated channel, Shal-related subfamily, member 37872-0.0290.1897No
76ESRRAESRRA
Entrez,  Source
estrogen-related receptor alpha8092-0.0330.1761No
77CAMKK2CAMKK2
Entrez,  Source
calcium/calmodulin-dependent protein kinase kinase 2, beta8568-0.0430.1439No
78RARARARA
Entrez,  Source
retinoic acid receptor, alpha8595-0.0430.1457No
79PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein8718-0.0460.1405No
80TFEBTFEB
Entrez,  Source
transcription factor EB8952-0.0510.1273No
81RAB10RAB10
Entrez,  Source
RAB10, member RAS oncogene family9126-0.0550.1190No
82SONSON
Entrez,  Source
SON DNA binding protein9229-0.0570.1162No
83GAD1GAD1
Entrez,  Source
glutamate decarboxylase 1 (brain, 67kDa)9270-0.0570.1182No
84SFRS7SFRS7
Entrez,  Source
splicing factor, arginine/serine-rich 7, 35kDa9277-0.0580.1227No
85BTBD14BBTBD14B
Entrez,  Source
BTB (POZ) domain containing 14B9670-0.0670.0989No
86UBE2D3UBE2D3
Entrez,  Source
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)9797-0.0710.0956No
87DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)9896-0.0740.0946No
88PHF12PHF12
Entrez,  Source
PHD finger protein 129978-0.0760.0950No
89TIMM10TIMM10
Entrez,  Source
translocase of inner mitochondrial membrane 10 homolog (yeast)10050-0.0780.0965No
90PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)10272-0.0840.0870No
91IL11IL11
Entrez,  Source
interleukin 1110348-0.0860.0888No
92AMD1AMD1
Entrez,  Source
adenosylmethionine decarboxylase 110528-0.0910.0832No
93EIF4G1EIF4G1
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 110984-0.1080.0582No
94DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1711050-0.1100.0629No
95ADMADM
Entrez,  Source
adrenomedullin11063-0.1100.0716No
96PDGFRLPDGFRL
Entrez,  Source
platelet-derived growth factor receptor-like11182-0.1160.0727No
97PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 211205-0.1160.0811No
98ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein11229-0.1170.0896No
99POLR3CPOLR3C
Entrez,  Source
polymerase (RNA) III (DNA directed) polypeptide C (62kD)11398-0.1250.0877No
100BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 111682-0.1370.0783No
101ARID4BARID4B
Entrez,  Source
AT rich interactive domain 4B (RBP1- like)12232-0.1740.0519No
102ADNPADNP
Entrez,  Source
activity-dependent neuroprotector12323-0.1810.0609No
103NR1D1NR1D1
Entrez,  Source
nuclear receptor subfamily 1, group D, member 112353-0.1840.0747No
Table: GSEA details [plain text format]



Fig 2: V$DR4_Q2   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: V$DR4_Q2: Random ES distribution   
Gene set null distribution of ES for V$DR4_Q2