Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F1_Q3 |
| Enrichment Score (ES) | -0.3507931 |
| Normalized Enrichment Score (NES) | -1.3283404 |
| Nominal p-value | 0.0487239 |
| FDR q-value | 0.38037103 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 100 | 0.661 | 0.0560 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 293 | 0.407 | 0.0807 | No |
| 3 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.1189 | No |
| 4 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 442 | 0.313 | 0.1383 | No |
| 5 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 597 | 0.258 | 0.1514 | No |
| 6 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 724 | 0.231 | 0.1641 | No |
| 7 | ASCL1 | ASCL1 Entrez, Source | achaete-scute complex-like 1 (Drosophila) | 2026 | 0.107 | 0.0762 | No |
| 8 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0633 | No |
| 9 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 2376 | 0.093 | 0.0679 | No |
| 10 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 2578 | 0.084 | 0.0609 | No |
| 11 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2696 | 0.080 | 0.0597 | No |
| 12 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2790 | 0.077 | 0.0601 | No |
| 13 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 2867 | 0.075 | 0.0616 | No |
| 14 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.0211 | No |
| 15 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 3514 | 0.057 | 0.0240 | No |
| 16 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3580 | 0.055 | 0.0245 | No |
| 17 | ATP1B4 | ATP1B4 Entrez, Source | ATPase, (Na+)/K+ transporting, beta 4 polypeptide | 3612 | 0.054 | 0.0274 | No |
| 18 | CORT | CORT Entrez, Source | cortistatin | 3683 | 0.053 | 0.0271 | No |
| 19 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 3905 | 0.047 | 0.0150 | No |
| 20 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | 0.0042 | No |
| 21 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.0015 | No |
| 22 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 4503 | 0.034 | -0.0189 | No |
| 23 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4552 | 0.033 | -0.0193 | No |
| 24 | BARHL1 | BARHL1 Entrez, Source | BarH-like 1 (Drosophila) | 4685 | 0.030 | -0.0264 | No |
| 25 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 4806 | 0.028 | -0.0328 | No |
| 26 | SYT11 | SYT11 Entrez, Source | synaptotagmin XI | 4918 | 0.026 | -0.0387 | No |
| 27 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.0550 | No |
| 28 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 5268 | 0.019 | -0.0610 | No |
| 29 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5474 | 0.015 | -0.0750 | No |
| 30 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5481 | 0.015 | -0.0740 | No |
| 31 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 5640 | 0.012 | -0.0848 | No |
| 32 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 5869 | 0.008 | -0.1012 | No |
| 33 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 6034 | 0.005 | -0.1132 | No |
| 34 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6149 | 0.002 | -0.1216 | No |
| 35 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 6351 | -0.001 | -0.1367 | No |
| 36 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.1386 | No |
| 37 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | -0.1415 | No |
| 38 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 6480 | -0.003 | -0.1455 | No |
| 39 | BAT3 | BAT3 Entrez, Source | HLA-B associated transcript 3 | 6518 | -0.004 | -0.1479 | No |
| 40 | GRIK2 | GRIK2 Entrez, Source | glutamate receptor, ionotropic, kainate 2 | 7092 | -0.014 | -0.1898 | No |
| 41 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7148 | -0.015 | -0.1926 | No |
| 42 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7291 | -0.018 | -0.2016 | No |
| 43 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 7509 | -0.022 | -0.2159 | No |
| 44 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2209 | No |
| 45 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 7683 | -0.025 | -0.2242 | No |
| 46 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | -0.2253 | No |
| 47 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 7818 | -0.028 | -0.2291 | No |
| 48 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 7827 | -0.028 | -0.2270 | No |
| 49 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 8351 | -0.038 | -0.2628 | No |
| 50 | PELP1 | PELP1 Entrez, Source | proline, glutamic acid and leucine rich protein 1 | 8455 | -0.041 | -0.2667 | No |
| 51 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.2641 | No |
| 52 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 8586 | -0.043 | -0.2683 | No |
| 53 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 8695 | -0.045 | -0.2721 | No |
| 54 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9009 | -0.052 | -0.2907 | No |
| 55 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9249 | -0.057 | -0.3033 | No |
| 56 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.2998 | No |
| 57 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 9688 | -0.068 | -0.3242 | No |
| 58 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 9887 | -0.073 | -0.3321 | No |
| 59 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 9896 | -0.074 | -0.3256 | No |
| 60 | ADCY8 | ADCY8 Entrez, Source | adenylate cyclase 8 (brain) | 9950 | -0.075 | -0.3224 | No |
| 61 | PHF12 | PHF12 Entrez, Source | PHD finger protein 12 | 9978 | -0.076 | -0.3172 | No |
| 62 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.3264 | No |
| 63 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3296 | No |
| 64 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.3270 | No |
| 65 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3205 | No |
| 66 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 10515 | -0.091 | -0.3154 | No |
| 67 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.3111 | No |
| 68 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 10898 | -0.105 | -0.3251 | No |
| 69 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 11239 | -0.117 | -0.3395 | Yes |
| 70 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 11249 | -0.118 | -0.3288 | Yes |
| 71 | ABCE1 | ABCE1 Entrez, Source | ATP-binding cassette, sub-family E (OABP), member 1 | 11335 | -0.122 | -0.3236 | Yes |
| 72 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.3199 | Yes |
| 73 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 11453 | -0.127 | -0.3079 | Yes |
| 74 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11546 | -0.131 | -0.3022 | Yes |
| 75 | SSBP3 | SSBP3 Entrez, Source | single stranded DNA binding protein 3 | 11675 | -0.137 | -0.2987 | Yes |
| 76 | XTP3TPA | XTP3TPA Entrez, Source | - | 12079 | -0.163 | -0.3135 | Yes |
| 77 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12095 | -0.164 | -0.2989 | Yes |
| 78 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.2932 | Yes |
| 79 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12298 | -0.179 | -0.2800 | Yes |
| 80 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2654 | Yes |
| 81 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.2661 | Yes |
| 82 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 12629 | -0.215 | -0.2460 | Yes |
| 83 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.2368 | Yes |
| 84 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2148 | Yes |
| 85 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.1946 | Yes |
| 86 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1706 | Yes |
| 87 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 13014 | -0.296 | -0.1436 | Yes |
| 88 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.1186 | Yes |
| 89 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.0865 | Yes |
| 90 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0446 | Yes |
| 91 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
