Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F1_Q6_01 |
| Enrichment Score (ES) | -0.4100918 |
| Normalized Enrichment Score (NES) | -1.5319657 |
| Nominal p-value | 0.004750594 |
| FDR q-value | 0.2196941 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 207 | 0.480 | 0.0245 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 293 | 0.407 | 0.0522 | No |
| 3 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 412 | 0.330 | 0.0710 | No |
| 4 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 442 | 0.313 | 0.0950 | No |
| 5 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 509 | 0.282 | 0.1136 | No |
| 6 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 597 | 0.258 | 0.1286 | No |
| 7 | FZD1 | FZD1 Entrez, Source | frizzled homolog 1 (Drosophila) | 708 | 0.233 | 0.1398 | No |
| 8 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 724 | 0.231 | 0.1580 | No |
| 9 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 940 | 0.189 | 0.1576 | No |
| 10 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 1290 | 0.152 | 0.1439 | No |
| 11 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0743 | No |
| 12 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 2548 | 0.086 | 0.0642 | No |
| 13 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2790 | 0.077 | 0.0525 | No |
| 14 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 2867 | 0.075 | 0.0531 | No |
| 15 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3071 | 0.069 | 0.0435 | No |
| 16 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.0177 | No |
| 17 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | -0.0257 | No |
| 18 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 4204 | 0.039 | -0.0300 | No |
| 19 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.0286 | No |
| 20 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 4469 | 0.035 | -0.0437 | No |
| 21 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 4503 | 0.034 | -0.0434 | No |
| 22 | SPHK2 | SPHK2 Entrez, Source | sphingosine kinase 2 | 4673 | 0.031 | -0.0536 | No |
| 23 | HR | HR Entrez, Source | hairless homolog (mouse) | 4958 | 0.025 | -0.0729 | No |
| 24 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.0865 | No |
| 25 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5474 | 0.015 | -0.1087 | No |
| 26 | SYT6 | SYT6 Entrez, Source | synaptotagmin VI | 5481 | 0.015 | -0.1079 | No |
| 27 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 6034 | 0.005 | -0.1491 | No |
| 28 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 6089 | 0.003 | -0.1529 | No |
| 29 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6149 | 0.002 | -0.1572 | No |
| 30 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6181 | 0.001 | -0.1594 | No |
| 31 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 6411 | -0.002 | -0.1765 | No |
| 32 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1807 | No |
| 33 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.1933 | No |
| 34 | DHH | DHH Entrez, Source | desert hedgehog homolog (Drosophila) | 6747 | -0.008 | -0.2002 | No |
| 35 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7148 | -0.015 | -0.2292 | No |
| 36 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7154 | -0.015 | -0.2283 | No |
| 37 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7291 | -0.018 | -0.2371 | No |
| 38 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2588 | No |
| 39 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 7672 | -0.025 | -0.2616 | No |
| 40 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | -0.2639 | No |
| 41 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 8351 | -0.038 | -0.3073 | No |
| 42 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 8374 | -0.039 | -0.3057 | No |
| 43 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 8429 | -0.040 | -0.3065 | No |
| 44 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.3064 | No |
| 45 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 8586 | -0.043 | -0.3111 | No |
| 46 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 8695 | -0.045 | -0.3155 | No |
| 47 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9009 | -0.052 | -0.3348 | No |
| 48 | ENPP1 | ENPP1 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 9193 | -0.056 | -0.3439 | No |
| 49 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 9324 | -0.059 | -0.3488 | No |
| 50 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | -0.3481 | No |
| 51 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.4032 | Yes |
| 52 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 10287 | -0.084 | -0.4023 | Yes |
| 53 | FAF1 | FAF1 Entrez, Source | Fas (TNFRSF6) associated factor 1 | 10352 | -0.086 | -0.4000 | Yes |
| 54 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3932 | Yes |
| 55 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3937 | Yes |
| 56 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 10528 | -0.091 | -0.3907 | Yes |
| 57 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 10541 | -0.091 | -0.3840 | Yes |
| 58 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.3790 | Yes |
| 59 | RPL18 | RPL18 Entrez, Source | ribosomal protein L18 | 10646 | -0.095 | -0.3760 | Yes |
| 60 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 10675 | -0.096 | -0.3701 | Yes |
| 61 | POU2F1 | POU2F1 Entrez, Source | POU domain, class 2, transcription factor 1 | 10684 | -0.097 | -0.3626 | Yes |
| 62 | MGAT2 | MGAT2 Entrez, Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 10868 | -0.104 | -0.3678 | Yes |
| 63 | TCF8 | TCF8 Entrez, Source | transcription factor 8 (represses interleukin 2 expression) | 10979 | -0.107 | -0.3671 | Yes |
| 64 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11050 | -0.110 | -0.3631 | Yes |
| 65 | TRIM39 | TRIM39 Entrez, Source | tripartite motif-containing 39 | 11239 | -0.117 | -0.3675 | Yes |
| 66 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 11310 | -0.121 | -0.3627 | Yes |
| 67 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.3625 | Yes |
| 68 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 11867 | -0.148 | -0.3815 | Yes |
| 69 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 11948 | -0.154 | -0.3747 | Yes |
| 70 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11964 | -0.154 | -0.3629 | Yes |
| 71 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3503 | Yes |
| 72 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.3421 | Yes |
| 73 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.3292 | Yes |
| 74 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12095 | -0.164 | -0.3190 | Yes |
| 75 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12145 | -0.168 | -0.3086 | Yes |
| 76 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 12159 | -0.169 | -0.2955 | Yes |
| 77 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.2872 | Yes |
| 78 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.2728 | Yes |
| 79 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2642 | Yes |
| 80 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.2676 | Yes |
| 81 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 12683 | -0.222 | -0.2536 | Yes |
| 82 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2412 | Yes |
| 83 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2253 | Yes |
| 84 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.2085 | Yes |
| 85 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.1858 | Yes |
| 86 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 12969 | -0.282 | -0.1640 | Yes |
| 87 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1414 | Yes |
| 88 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.1212 | Yes |
| 89 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.0953 | Yes |
| 90 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13151 | -0.360 | -0.0688 | Yes |
| 91 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0377 | Yes |
| 92 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
