Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F4DP1_01 |
| Enrichment Score (ES) | -0.37692255 |
| Normalized Enrichment Score (NES) | -1.4222366 |
| Nominal p-value | 0.0074812965 |
| FDR q-value | 0.272634 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 100 | 0.661 | 0.0461 | No |
| 2 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 255 | 0.437 | 0.0699 | No |
| 3 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 293 | 0.407 | 0.1001 | No |
| 4 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.1322 | No |
| 5 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 412 | 0.330 | 0.1506 | No |
| 6 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 442 | 0.313 | 0.1738 | No |
| 7 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 597 | 0.258 | 0.1831 | No |
| 8 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 940 | 0.189 | 0.1726 | No |
| 9 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 1295 | 0.151 | 0.1582 | No |
| 10 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1784 | 0.118 | 0.1309 | No |
| 11 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0982 | No |
| 12 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 2376 | 0.093 | 0.1015 | No |
| 13 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 2578 | 0.084 | 0.0932 | No |
| 14 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2696 | 0.080 | 0.0909 | No |
| 15 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2790 | 0.077 | 0.0901 | No |
| 16 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.0429 | No |
| 17 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 3514 | 0.057 | 0.0449 | No |
| 18 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3580 | 0.055 | 0.0445 | No |
| 19 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 3623 | 0.054 | 0.0457 | No |
| 20 | CORT | CORT Entrez, Source | cortistatin | 3683 | 0.053 | 0.0456 | No |
| 21 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 3894 | 0.047 | 0.0335 | No |
| 22 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | 0.0213 | No |
| 23 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | 0.0150 | No |
| 24 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 4716 | 0.030 | -0.0193 | No |
| 25 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.0512 | No |
| 26 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 5268 | 0.019 | -0.0575 | No |
| 27 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5474 | 0.015 | -0.0717 | No |
| 28 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 5640 | 0.012 | -0.0832 | No |
| 29 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5643 | 0.012 | -0.0824 | No |
| 30 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 6034 | 0.005 | -0.1115 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6149 | 0.002 | -0.1199 | No |
| 32 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 6349 | -0.001 | -0.1348 | No |
| 33 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.1370 | No |
| 34 | CDC5L | CDC5L Entrez, Source | CDC5 cell division cycle 5-like (S. pombe) | 6411 | -0.002 | -0.1391 | No |
| 35 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | -0.1397 | No |
| 36 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1431 | No |
| 37 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 6480 | -0.003 | -0.1434 | No |
| 38 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.1553 | No |
| 39 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 6679 | -0.007 | -0.1572 | No |
| 40 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7148 | -0.015 | -0.1913 | No |
| 41 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7291 | -0.018 | -0.2006 | No |
| 42 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2224 | No |
| 43 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 7672 | -0.025 | -0.2253 | No |
| 44 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 7707 | -0.025 | -0.2258 | No |
| 45 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | -0.2255 | No |
| 46 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 7897 | -0.029 | -0.2355 | No |
| 47 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 8351 | -0.038 | -0.2666 | No |
| 48 | GATA1 | GATA1 Entrez, Source | GATA binding protein 1 (globin transcription factor 1) | 8429 | -0.040 | -0.2692 | No |
| 49 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.2692 | No |
| 50 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 8586 | -0.043 | -0.2741 | No |
| 51 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 8695 | -0.045 | -0.2785 | No |
| 52 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9009 | -0.052 | -0.2979 | No |
| 53 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9249 | -0.057 | -0.3114 | No |
| 54 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.3087 | No |
| 55 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 9324 | -0.059 | -0.3074 | No |
| 56 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | -0.3069 | No |
| 57 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 9601 | -0.065 | -0.3180 | No |
| 58 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 9688 | -0.068 | -0.3191 | No |
| 59 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 9808 | -0.071 | -0.3223 | No |
| 60 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 9887 | -0.073 | -0.3222 | No |
| 61 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 9896 | -0.074 | -0.3169 | No |
| 62 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 10181 | -0.081 | -0.3317 | No |
| 63 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.3268 | No |
| 64 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.3372 | No |
| 65 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3320 | No |
| 66 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 10508 | -0.090 | -0.3277 | No |
| 67 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 10515 | -0.091 | -0.3208 | No |
| 68 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.3180 | No |
| 69 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 10766 | -0.100 | -0.3241 | No |
| 70 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 11080 | -0.111 | -0.3387 | No |
| 71 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.3561 | No |
| 72 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11546 | -0.131 | -0.3528 | No |
| 73 | KCNS2 | KCNS2 Entrez, Source | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2 | 11867 | -0.148 | -0.3649 | Yes |
| 74 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3600 | Yes |
| 75 | XTP3TPA | XTP3TPA Entrez, Source | - | 12079 | -0.163 | -0.3550 | Yes |
| 76 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12095 | -0.164 | -0.3428 | Yes |
| 77 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3398 | Yes |
| 78 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.3259 | Yes |
| 79 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.3175 | Yes |
| 80 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.3030 | Yes |
| 81 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.3069 | Yes |
| 82 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12748 | -0.232 | -0.2975 | Yes |
| 83 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12773 | -0.237 | -0.2801 | Yes |
| 84 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2615 | Yes |
| 85 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2463 | Yes |
| 86 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12917 | -0.270 | -0.2289 | Yes |
| 87 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.2083 | Yes |
| 88 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1887 | Yes |
| 89 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 13014 | -0.296 | -0.1661 | Yes |
| 90 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.1461 | Yes |
| 91 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.1204 | Yes |
| 92 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0851 | Yes |
| 93 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | -0.0447 | Yes |
| 94 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13299 | -0.601 | 0.0032 | Yes |
