Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F_01 |
| Enrichment Score (ES) | -0.45265785 |
| Normalized Enrichment Score (NES) | -1.4014927 |
| Nominal p-value | 0.07236842 |
| FDR q-value | 0.2890888 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 207 | 0.480 | 0.0822 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.1572 | No |
| 3 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 1690 | 0.123 | 0.0780 | No |
| 4 | GATA6 | GATA6 Entrez, Source | GATA binding protein 6 | 2206 | 0.099 | 0.0594 | No |
| 5 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0703 | No |
| 6 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 2744 | 0.079 | 0.0545 | No |
| 7 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3101 | 0.068 | 0.0417 | No |
| 8 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 4753 | 0.029 | -0.0765 | No |
| 9 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 5060 | 0.023 | -0.0948 | No |
| 10 | NLGN3 | NLGN3 Entrez, Source | neuroligin 3 | 5467 | 0.016 | -0.1222 | No |
| 11 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | -0.1934 | No |
| 12 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2775 | No |
| 13 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.3343 | No |
| 14 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 9093 | -0.054 | -0.3697 | No |
| 15 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 9324 | -0.059 | -0.3750 | No |
| 16 | ECEL1 | ECEL1 Entrez, Source | endothelin converting enzyme-like 1 | 9326 | -0.059 | -0.3631 | No |
| 17 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.4305 | Yes |
| 18 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 10528 | -0.091 | -0.4166 | Yes |
| 19 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 10924 | -0.106 | -0.4247 | Yes |
| 20 | SFMBT1 | SFMBT1 Entrez, Source | Scm-like with four mbt domains 1 | 11109 | -0.112 | -0.4156 | Yes |
| 21 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.4152 | Yes |
| 22 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 11948 | -0.154 | -0.4214 | Yes |
| 23 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3913 | Yes |
| 24 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.3644 | Yes |
| 25 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.3437 | Yes |
| 26 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12304 | -0.180 | -0.3111 | Yes |
| 27 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 12323 | -0.181 | -0.2755 | Yes |
| 28 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2394 | Yes |
| 29 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.2170 | Yes |
| 30 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 12789 | -0.239 | -0.1809 | Yes |
| 31 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1369 | Yes |
| 32 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13151 | -0.360 | -0.0753 | Yes |
| 33 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | 0.0086 | Yes |
