Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F_03 |
| Enrichment Score (ES) | -0.40942028 |
| Normalized Enrichment Score (NES) | -1.5353601 |
| Nominal p-value | 0.012077294 |
| FDR q-value | 0.22755805 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LGALS1 | LGALS1 Entrez, Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 82 | 0.687 | 0.0470 | No |
| 2 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 158 | 0.552 | 0.0840 | No |
| 3 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 293 | 0.407 | 0.1054 | No |
| 4 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 412 | 0.330 | 0.1221 | No |
| 5 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 764 | 0.223 | 0.1128 | No |
| 6 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1784 | 0.118 | 0.0450 | No |
| 7 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 1796 | 0.117 | 0.0532 | No |
| 8 | VAMP3 | VAMP3 Entrez, Source | vesicle-associated membrane protein 3 (cellubrevin) | 2057 | 0.105 | 0.0418 | No |
| 9 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0294 | No |
| 10 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 2376 | 0.093 | 0.0323 | No |
| 11 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2444 | 0.090 | 0.0342 | No |
| 12 | SF4 | SF4 Entrez, Source | splicing factor 4 | 2610 | 0.083 | 0.0282 | No |
| 13 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2696 | 0.080 | 0.0280 | No |
| 14 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 2867 | 0.075 | 0.0210 | No |
| 15 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3071 | 0.069 | 0.0110 | No |
| 16 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | -0.0152 | No |
| 17 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3580 | 0.055 | -0.0185 | No |
| 18 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 3862 | 0.048 | -0.0359 | No |
| 19 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 3905 | 0.047 | -0.0355 | No |
| 20 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | -0.0470 | No |
| 21 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 4352 | 0.037 | -0.0629 | No |
| 22 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 4503 | 0.034 | -0.0716 | No |
| 23 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 4552 | 0.033 | -0.0727 | No |
| 24 | ARF3 | ARF3 Entrez, Source | ADP-ribosylation factor 3 | 4689 | 0.030 | -0.0806 | No |
| 25 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 5060 | 0.023 | -0.1068 | No |
| 26 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 5643 | 0.012 | -0.1498 | No |
| 27 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 5869 | 0.008 | -0.1662 | No |
| 28 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 6089 | 0.003 | -0.1824 | No |
| 29 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.2042 | No |
| 30 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | -0.2072 | No |
| 31 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 6700 | -0.007 | -0.2275 | No |
| 32 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 7017 | -0.013 | -0.2504 | No |
| 33 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7154 | -0.015 | -0.2595 | No |
| 34 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7291 | -0.018 | -0.2684 | No |
| 35 | ATP6V1D | ATP6V1D Entrez, Source | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 7326 | -0.018 | -0.2696 | No |
| 36 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 7404 | -0.020 | -0.2738 | No |
| 37 | SLC25A11 | SLC25A11 Entrez, Source | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 7432 | -0.020 | -0.2743 | No |
| 38 | CACNA1G | CACNA1G Entrez, Source | calcium channel, voltage-dependent, alpha 1G subunit | 7509 | -0.022 | -0.2783 | No |
| 39 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 7584 | -0.023 | -0.2821 | No |
| 40 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2819 | No |
| 41 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 8374 | -0.039 | -0.3368 | No |
| 42 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.3411 | No |
| 43 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 8685 | -0.045 | -0.3534 | No |
| 44 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 8941 | -0.051 | -0.3688 | No |
| 45 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9009 | -0.052 | -0.3698 | No |
| 46 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9249 | -0.057 | -0.3834 | No |
| 47 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | -0.3887 | No |
| 48 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 9463 | -0.062 | -0.3900 | No |
| 49 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 9688 | -0.068 | -0.4017 | No |
| 50 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 9713 | -0.068 | -0.3982 | No |
| 51 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 9714 | -0.068 | -0.3929 | No |
| 52 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 9808 | -0.071 | -0.3944 | No |
| 53 | RPL28 | RPL28 Entrez, Source | ribosomal protein L28 | 9854 | -0.073 | -0.3922 | No |
| 54 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 9887 | -0.073 | -0.3890 | No |
| 55 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 9896 | -0.074 | -0.3839 | No |
| 56 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 10178 | -0.081 | -0.3988 | No |
| 57 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.3944 | No |
| 58 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3993 | No |
| 59 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.3984 | No |
| 60 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3935 | No |
| 61 | SIAHBP1 | SIAHBP1 Entrez, Source | - | 10678 | -0.096 | -0.4020 | Yes |
| 62 | RPS20 | RPS20 Entrez, Source | ribosomal protein S20 | 10766 | -0.100 | -0.4008 | Yes |
| 63 | EIF4G2 | EIF4G2 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 2 | 10777 | -0.100 | -0.3939 | Yes |
| 64 | TCP1 | TCP1 Entrez, Source | t-complex 1 | 10898 | -0.105 | -0.3948 | Yes |
| 65 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11050 | -0.110 | -0.3977 | Yes |
| 66 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 11091 | -0.112 | -0.3921 | Yes |
| 67 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 11114 | -0.113 | -0.3850 | Yes |
| 68 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11128 | -0.113 | -0.3772 | Yes |
| 69 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 11453 | -0.127 | -0.3918 | Yes |
| 70 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 11644 | -0.136 | -0.3957 | Yes |
| 71 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 11725 | -0.140 | -0.3909 | Yes |
| 72 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 11739 | -0.140 | -0.3811 | Yes |
| 73 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11964 | -0.154 | -0.3860 | Yes |
| 74 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3744 | Yes |
| 75 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11979 | -0.156 | -0.3629 | Yes |
| 76 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12006 | -0.158 | -0.3527 | Yes |
| 77 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.3427 | Yes |
| 78 | XTP3TPA | XTP3TPA Entrez, Source | - | 12079 | -0.163 | -0.3330 | Yes |
| 79 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3319 | Yes |
| 80 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 12249 | -0.175 | -0.3186 | Yes |
| 81 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.3112 | Yes |
| 82 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 12585 | -0.209 | -0.3135 | Yes |
| 83 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12830 | -0.249 | -0.3127 | Yes |
| 84 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12917 | -0.270 | -0.2982 | Yes |
| 85 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.2790 | Yes |
| 86 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.2601 | Yes |
| 87 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 13014 | -0.296 | -0.2386 | Yes |
| 88 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13034 | -0.303 | -0.2166 | Yes |
| 89 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.1954 | Yes |
| 90 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.1715 | Yes |
| 91 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 13218 | -0.424 | -0.1474 | Yes |
| 92 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.1145 | Yes |
| 93 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0808 | Yes |
| 94 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | -0.0425 | Yes |
| 95 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13299 | -0.601 | 0.0032 | Yes |
