Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$E2F_Q4 |
| Enrichment Score (ES) | -0.38776547 |
| Normalized Enrichment Score (NES) | -1.4351336 |
| Nominal p-value | 0.02905569 |
| FDR q-value | 0.26487324 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 100 | 0.661 | 0.0525 | No |
| 2 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 293 | 0.407 | 0.0751 | No |
| 3 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.1112 | No |
| 4 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 442 | 0.313 | 0.1289 | No |
| 5 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 597 | 0.258 | 0.1408 | No |
| 6 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 647 | 0.246 | 0.1594 | No |
| 7 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 940 | 0.189 | 0.1546 | No |
| 8 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 1676 | 0.124 | 0.1104 | No |
| 9 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 2319 | 0.095 | 0.0705 | No |
| 10 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 2376 | 0.093 | 0.0747 | No |
| 11 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 2578 | 0.084 | 0.0672 | No |
| 12 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 2696 | 0.080 | 0.0657 | No |
| 13 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2790 | 0.077 | 0.0657 | No |
| 14 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 3071 | 0.069 | 0.0508 | No |
| 15 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 3479 | 0.058 | 0.0254 | No |
| 16 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 3514 | 0.057 | 0.0280 | No |
| 17 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3580 | 0.055 | 0.0282 | No |
| 18 | CORT | CORT Entrez, Source | cortistatin | 3683 | 0.053 | 0.0252 | No |
| 19 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4102 | 0.042 | -0.0025 | No |
| 20 | TMPO | TMPO Entrez, Source | thymopoietin | 4229 | 0.039 | -0.0084 | No |
| 21 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 4511 | 0.034 | -0.0266 | No |
| 22 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 4996 | 0.024 | -0.0609 | No |
| 23 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 5060 | 0.023 | -0.0636 | No |
| 24 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 5162 | 0.021 | -0.0693 | No |
| 25 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 5268 | 0.019 | -0.0755 | No |
| 26 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5474 | 0.015 | -0.0895 | No |
| 27 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 5640 | 0.012 | -0.1009 | No |
| 28 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 6034 | 0.005 | -0.1301 | No |
| 29 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 6089 | 0.003 | -0.1339 | No |
| 30 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6149 | 0.002 | -0.1381 | No |
| 31 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 6380 | -0.001 | -0.1554 | No |
| 32 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 6422 | -0.002 | -0.1583 | No |
| 33 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1616 | No |
| 34 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 6480 | -0.003 | -0.1619 | No |
| 35 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6646 | -0.006 | -0.1738 | No |
| 36 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 7148 | -0.015 | -0.2103 | No |
| 37 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 7154 | -0.015 | -0.2093 | No |
| 38 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 7291 | -0.018 | -0.2180 | No |
| 39 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 7584 | -0.023 | -0.2379 | No |
| 40 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 7606 | -0.024 | -0.2373 | No |
| 41 | EFNA5 | EFNA5 Entrez, Source | ephrin-A5 | 7672 | -0.025 | -0.2400 | No |
| 42 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 7732 | -0.026 | -0.2421 | No |
| 43 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 7897 | -0.029 | -0.2518 | No |
| 44 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 8351 | -0.038 | -0.2825 | No |
| 45 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 8374 | -0.039 | -0.2806 | No |
| 46 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8474 | -0.041 | -0.2844 | No |
| 47 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 8586 | -0.043 | -0.2888 | No |
| 48 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 8695 | -0.045 | -0.2928 | No |
| 49 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 8752 | -0.047 | -0.2928 | No |
| 50 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 9009 | -0.052 | -0.3074 | No |
| 51 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9249 | -0.057 | -0.3203 | No |
| 52 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 9277 | -0.058 | -0.3171 | No |
| 53 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | -0.3195 | No |
| 54 | FANCD2 | FANCD2 Entrez, Source | Fanconi anemia, complementation group D2 | 9601 | -0.065 | -0.3300 | No |
| 55 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 9688 | -0.068 | -0.3303 | No |
| 56 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 9887 | -0.073 | -0.3386 | No |
| 57 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 9896 | -0.074 | -0.3325 | No |
| 58 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9974 | -0.076 | -0.3314 | No |
| 59 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 10205 | -0.082 | -0.3414 | No |
| 60 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3451 | No |
| 61 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 10438 | -0.088 | -0.3429 | No |
| 62 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 10466 | -0.089 | -0.3369 | No |
| 63 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 10515 | -0.091 | -0.3323 | No |
| 64 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 10578 | -0.093 | -0.3285 | No |
| 65 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11050 | -0.110 | -0.3541 | No |
| 66 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 11128 | -0.113 | -0.3496 | No |
| 67 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11449 | -0.127 | -0.3622 | No |
| 68 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11546 | -0.131 | -0.3575 | No |
| 69 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 11948 | -0.154 | -0.3738 | Yes |
| 70 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 11964 | -0.154 | -0.3609 | Yes |
| 71 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3472 | Yes |
| 72 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11979 | -0.156 | -0.3336 | Yes |
| 73 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 12039 | -0.160 | -0.3235 | Yes |
| 74 | XTP3TPA | XTP3TPA Entrez, Source | - | 12079 | -0.163 | -0.3117 | Yes |
| 75 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 12095 | -0.164 | -0.2979 | Yes |
| 76 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 12159 | -0.169 | -0.2873 | Yes |
| 77 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.2778 | Yes |
| 78 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12334 | -0.182 | -0.2680 | Yes |
| 79 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2517 | Yes |
| 80 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12477 | -0.196 | -0.2442 | Yes |
| 81 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 12621 | -0.214 | -0.2356 | Yes |
| 82 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2301 | Yes |
| 83 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.2114 | Yes |
| 84 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 12994 | -0.291 | -0.1889 | Yes |
| 85 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 13014 | -0.296 | -0.1634 | Yes |
| 86 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.1394 | Yes |
| 87 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13101 | -0.328 | -0.1112 | Yes |
| 88 | DCK | DCK Entrez, Source | deoxycytidine kinase | 13222 | -0.428 | -0.0813 | Yes |
| 89 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0417 | Yes |
| 90 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | 0.0041 | Yes |
