Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$MAX_01 |
| Enrichment Score (ES) | -0.40581504 |
| Normalized Enrichment Score (NES) | -1.5874459 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.17203124 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 84 | 0.686 | 0.0430 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.0556 | No |
| 3 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 316 | 0.387 | 0.0823 | No |
| 4 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 631 | 0.249 | 0.0765 | No |
| 5 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 783 | 0.219 | 0.0808 | No |
| 6 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 819 | 0.210 | 0.0933 | No |
| 7 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.0999 | No |
| 8 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 970 | 0.186 | 0.1093 | No |
| 9 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.0981 | No |
| 10 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 1271 | 0.153 | 0.1088 | No |
| 11 | LZTFL1 | LZTFL1 Entrez, Source | leucine zipper transcription factor-like 1 | 1350 | 0.147 | 0.1135 | No |
| 12 | DZIP1 | DZIP1 Entrez, Source | DAZ interacting protein 1 | 1960 | 0.109 | 0.0753 | No |
| 13 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1993 | 0.108 | 0.0806 | No |
| 14 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 2030 | 0.106 | 0.0856 | No |
| 15 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2385 | 0.092 | 0.0654 | No |
| 16 | MAX | MAX Entrez, Source | MYC associated factor X | 2495 | 0.088 | 0.0635 | No |
| 17 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 2507 | 0.088 | 0.0690 | No |
| 18 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 2545 | 0.086 | 0.0724 | No |
| 19 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 2549 | 0.086 | 0.0783 | No |
| 20 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3101 | 0.068 | 0.0416 | No |
| 21 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 3348 | 0.061 | 0.0274 | No |
| 22 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 3403 | 0.060 | 0.0276 | No |
| 23 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 3423 | 0.060 | 0.0305 | No |
| 24 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 3556 | 0.056 | 0.0245 | No |
| 25 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 3964 | 0.045 | -0.0030 | No |
| 26 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 4246 | 0.039 | -0.0214 | No |
| 27 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 4274 | 0.038 | -0.0207 | No |
| 28 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 4337 | 0.037 | -0.0228 | No |
| 29 | GNAS | GNAS Entrez, Source | GNAS complex locus | 4431 | 0.035 | -0.0273 | No |
| 30 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 4986 | 0.024 | -0.0674 | No |
| 31 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4993 | 0.024 | -0.0661 | No |
| 32 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5509 | 0.014 | -0.1040 | No |
| 33 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5716 | 0.011 | -0.1188 | No |
| 34 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 5801 | 0.009 | -0.1245 | No |
| 35 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 5876 | 0.008 | -0.1295 | No |
| 36 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 6092 | 0.003 | -0.1455 | No |
| 37 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 6161 | 0.002 | -0.1505 | No |
| 38 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 6213 | 0.001 | -0.1543 | No |
| 39 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 6295 | -0.000 | -0.1604 | No |
| 40 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 6338 | -0.001 | -0.1636 | No |
| 41 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.1733 | No |
| 42 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.1897 | No |
| 43 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 6749 | -0.008 | -0.1931 | No |
| 44 | ACY1 | ACY1 Entrez, Source | aminoacylase 1 | 6868 | -0.010 | -0.2013 | No |
| 45 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 7017 | -0.013 | -0.2116 | No |
| 46 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 7067 | -0.014 | -0.2143 | No |
| 47 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 7459 | -0.021 | -0.2424 | No |
| 48 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 7607 | -0.024 | -0.2518 | No |
| 49 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 7771 | -0.027 | -0.2622 | No |
| 50 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 7843 | -0.028 | -0.2655 | No |
| 51 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 7920 | -0.030 | -0.2691 | No |
| 52 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 8002 | -0.031 | -0.2730 | No |
| 53 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 8010 | -0.031 | -0.2713 | No |
| 54 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 8026 | -0.032 | -0.2701 | No |
| 55 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8085 | -0.033 | -0.2721 | No |
| 56 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8263 | -0.037 | -0.2829 | No |
| 57 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 8295 | -0.037 | -0.2825 | No |
| 58 | GUCY1A2 | GUCY1A2 Entrez, Source | guanylate cyclase 1, soluble, alpha 2 | 8381 | -0.039 | -0.2861 | No |
| 59 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 8436 | -0.040 | -0.2873 | No |
| 60 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 8462 | -0.041 | -0.2863 | No |
| 61 | IPO13 | IPO13 Entrez, Source | importin 13 | 8599 | -0.043 | -0.2934 | No |
| 62 | GGN | GGN Entrez, Source | gametogenetin | 8728 | -0.046 | -0.2998 | No |
| 63 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 8841 | -0.049 | -0.3048 | No |
| 64 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 9018 | -0.052 | -0.3143 | No |
| 65 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9112 | -0.054 | -0.3175 | No |
| 66 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 9339 | -0.059 | -0.3303 | No |
| 67 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 9447 | -0.062 | -0.3340 | No |
| 68 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9506 | -0.063 | -0.3338 | No |
| 69 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9594 | -0.065 | -0.3357 | No |
| 70 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 10050 | -0.078 | -0.3645 | No |
| 71 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10349 | -0.086 | -0.3808 | No |
| 72 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 10396 | -0.087 | -0.3780 | No |
| 73 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 10459 | -0.089 | -0.3763 | No |
| 74 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 10469 | -0.089 | -0.3706 | No |
| 75 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 10474 | -0.089 | -0.3644 | No |
| 76 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10485 | -0.090 | -0.3587 | No |
| 77 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 10765 | -0.099 | -0.3727 | No |
| 78 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 11066 | -0.111 | -0.3874 | No |
| 79 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 11249 | -0.118 | -0.3927 | No |
| 80 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 11382 | -0.124 | -0.3937 | No |
| 81 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 11489 | -0.129 | -0.3925 | No |
| 82 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11666 | -0.137 | -0.3960 | Yes |
| 83 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 11674 | -0.137 | -0.3867 | Yes |
| 84 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 11829 | -0.146 | -0.3878 | Yes |
| 85 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 11907 | -0.150 | -0.3828 | Yes |
| 86 | FKBP11 | FKBP11 Entrez, Source | FK506 binding protein 11, 19 kDa | 11942 | -0.153 | -0.3744 | Yes |
| 87 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 12007 | -0.158 | -0.3679 | Yes |
| 88 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.3594 | Yes |
| 89 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12098 | -0.164 | -0.3512 | Yes |
| 90 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 12176 | -0.170 | -0.3449 | Yes |
| 91 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.3374 | Yes |
| 92 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.3257 | Yes |
| 93 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12263 | -0.177 | -0.3133 | Yes |
| 94 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.3058 | Yes |
| 95 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 12345 | -0.183 | -0.2930 | Yes |
| 96 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 12366 | -0.185 | -0.2812 | Yes |
| 97 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12583 | -0.209 | -0.2825 | Yes |
| 98 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 12721 | -0.227 | -0.2766 | Yes |
| 99 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12748 | -0.232 | -0.2618 | Yes |
| 100 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2473 | Yes |
| 101 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.2325 | Yes |
| 102 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12936 | -0.273 | -0.2213 | Yes |
| 103 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.2019 | Yes |
| 104 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.1824 | Yes |
| 105 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 12959 | -0.279 | -0.1633 | Yes |
| 106 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.1438 | Yes |
| 107 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13030 | -0.302 | -0.1265 | Yes |
| 108 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13050 | -0.307 | -0.1058 | Yes |
| 109 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.0851 | Yes |
| 110 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 13111 | -0.334 | -0.0634 | Yes |
| 111 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13269 | -0.522 | -0.0378 | Yes |
| 112 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13299 | -0.601 | 0.0032 | Yes |
