Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$MYCMAX_01 |
| Enrichment Score (ES) | -0.4801018 |
| Normalized Enrichment Score (NES) | -1.8754115 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.023524037 |
| FWER p-Value | 0.547 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 316 | 0.387 | 0.0052 | No |
| 2 | CGREF1 | CGREF1 Entrez, Source | cell growth regulator with EF-hand domain 1 | 537 | 0.273 | 0.0091 | No |
| 3 | GPC3 | GPC3 Entrez, Source | glypican 3 | 757 | 0.224 | 0.0094 | No |
| 4 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 916 | 0.193 | 0.0120 | No |
| 5 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 926 | 0.191 | 0.0257 | No |
| 6 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 1319 | 0.149 | 0.0073 | No |
| 7 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1486 | 0.136 | 0.0050 | No |
| 8 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 1770 | 0.118 | -0.0075 | No |
| 9 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1870 | 0.113 | -0.0065 | No |
| 10 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1993 | 0.108 | -0.0076 | No |
| 11 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 2154 | 0.101 | -0.0120 | No |
| 12 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 2507 | 0.088 | -0.0321 | No |
| 13 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 2549 | 0.086 | -0.0287 | No |
| 14 | PPARGC1B | PPARGC1B Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, beta | 2782 | 0.077 | -0.0404 | No |
| 15 | G6PC3 | G6PC3 Entrez, Source | glucose 6 phosphatase, catalytic, 3 | 3011 | 0.071 | -0.0523 | No |
| 16 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 3101 | 0.068 | -0.0539 | No |
| 17 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 3403 | 0.060 | -0.0721 | No |
| 18 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 3423 | 0.060 | -0.0691 | No |
| 19 | PITX3 | PITX3 Entrez, Source | paired-like homeodomain transcription factor 3 | 3470 | 0.059 | -0.0682 | No |
| 20 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 3556 | 0.056 | -0.0704 | No |
| 21 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 3862 | 0.048 | -0.0898 | No |
| 22 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 3887 | 0.048 | -0.0880 | No |
| 23 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 3964 | 0.045 | -0.0903 | No |
| 24 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 4246 | 0.039 | -0.1087 | No |
| 25 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 4274 | 0.038 | -0.1079 | No |
| 26 | DIABLO | DIABLO Entrez, Source | diablo homolog (Drosophila) | 4276 | 0.038 | -0.1051 | No |
| 27 | KCMF1 | KCMF1 Entrez, Source | potassium channel modulatory factor 1 | 4680 | 0.030 | -0.1333 | No |
| 28 | SC65 | SC65 Entrez, Source | - | 4719 | 0.030 | -0.1339 | No |
| 29 | SLC6A15 | SLC6A15 Entrez, Source | solute carrier family 6, member 15 | 4739 | 0.029 | -0.1331 | No |
| 30 | RAMP2 | RAMP2 Entrez, Source | receptor (calcitonin) activity modifying protein 2 | 4826 | 0.027 | -0.1375 | No |
| 31 | ARL3 | ARL3 Entrez, Source | ADP-ribosylation factor-like 3 | 4846 | 0.027 | -0.1369 | No |
| 32 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 4953 | 0.025 | -0.1431 | No |
| 33 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 4986 | 0.024 | -0.1437 | No |
| 34 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4993 | 0.024 | -0.1423 | No |
| 35 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 5876 | 0.008 | -0.2084 | No |
| 36 | MPP3 | MPP3 Entrez, Source | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) | 5882 | 0.007 | -0.2082 | No |
| 37 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 6161 | 0.002 | -0.2291 | No |
| 38 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 6213 | 0.001 | -0.2328 | No |
| 39 | STXBP2 | STXBP2 Entrez, Source | syntaxin binding protein 2 | 6439 | -0.002 | -0.2497 | No |
| 40 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 6471 | -0.003 | -0.2518 | No |
| 41 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.2682 | No |
| 42 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 6749 | -0.008 | -0.2715 | No |
| 43 | ACY1 | ACY1 Entrez, Source | aminoacylase 1 | 6868 | -0.010 | -0.2797 | No |
| 44 | NRAS | NRAS Entrez, Source | neuroblastoma RAS viral (v-ras) oncogene homolog | 6918 | -0.011 | -0.2826 | No |
| 45 | WDR23 | WDR23 Entrez, Source | WD repeat domain 23 | 6960 | -0.012 | -0.2848 | No |
| 46 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 7017 | -0.013 | -0.2881 | No |
| 47 | POU3F2 | POU3F2 Entrez, Source | POU domain, class 3, transcription factor 2 | 7036 | -0.013 | -0.2885 | No |
| 48 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 7498 | -0.022 | -0.3217 | No |
| 49 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 7607 | -0.024 | -0.3281 | No |
| 50 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 7632 | -0.024 | -0.3281 | No |
| 51 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 7920 | -0.030 | -0.3475 | No |
| 52 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 7975 | -0.031 | -0.3493 | No |
| 53 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 8026 | -0.032 | -0.3507 | No |
| 54 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 8060 | -0.032 | -0.3508 | No |
| 55 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 8092 | -0.033 | -0.3506 | No |
| 56 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8263 | -0.037 | -0.3607 | No |
| 57 | FGF14 | FGF14 Entrez, Source | fibroblast growth factor 14 | 8295 | -0.037 | -0.3602 | No |
| 58 | FGF6 | FGF6 Entrez, Source | fibroblast growth factor 6 | 8436 | -0.040 | -0.3678 | No |
| 59 | IPO13 | IPO13 Entrez, Source | importin 13 | 8599 | -0.043 | -0.3768 | No |
| 60 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 8812 | -0.048 | -0.3892 | No |
| 61 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 8841 | -0.049 | -0.3877 | No |
| 62 | SLC12A5 | SLC12A5 Entrez, Source | solute carrier family 12, (potassium-chloride transporter) member 5 | 9114 | -0.054 | -0.4041 | No |
| 63 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 9204 | -0.056 | -0.4066 | No |
| 64 | RHEBL1 | RHEBL1 Entrez, Source | Ras homolog enriched in brain like 1 | 9295 | -0.058 | -0.4091 | No |
| 65 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 9339 | -0.059 | -0.4079 | No |
| 66 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 9434 | -0.061 | -0.4104 | No |
| 67 | KCNN4 | KCNN4 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 | 9973 | -0.076 | -0.4454 | No |
| 68 | GPS1 | GPS1 Entrez, Source | G protein pathway suppressor 1 | 10011 | -0.077 | -0.4424 | No |
| 69 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 10050 | -0.078 | -0.4394 | No |
| 70 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10135 | -0.080 | -0.4397 | No |
| 71 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 10349 | -0.086 | -0.4494 | No |
| 72 | QTRT1 | QTRT1 Entrez, Source | queuine tRNA-ribosyltransferase 1 (tRNA-guanine transglycosylase) | 10396 | -0.087 | -0.4463 | No |
| 73 | PUS1 | PUS1 Entrez, Source | pseudouridylate synthase 1 | 10418 | -0.088 | -0.4413 | No |
| 74 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 10459 | -0.089 | -0.4376 | No |
| 75 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 10469 | -0.089 | -0.4315 | No |
| 76 | LYAR | LYAR Entrez, Source | - | 10519 | -0.091 | -0.4284 | No |
| 77 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 11125 | -0.113 | -0.4656 | No |
| 78 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 11249 | -0.118 | -0.4661 | No |
| 79 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 11310 | -0.121 | -0.4615 | No |
| 80 | ATAD3A | ATAD3A Entrez, Source | ATPase family, AAA domain containing 3A | 11557 | -0.131 | -0.4702 | Yes |
| 81 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11646 | -0.136 | -0.4667 | Yes |
| 82 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11666 | -0.137 | -0.4578 | Yes |
| 83 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 11829 | -0.146 | -0.4591 | Yes |
| 84 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 11907 | -0.150 | -0.4536 | Yes |
| 85 | FKBP11 | FKBP11 Entrez, Source | FK506 binding protein 11, 19 kDa | 11942 | -0.153 | -0.4447 | Yes |
| 86 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.4350 | Yes |
| 87 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.4288 | Yes |
| 88 | XTP3TPA | XTP3TPA Entrez, Source | - | 12079 | -0.163 | -0.4188 | Yes |
| 89 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.4180 | Yes |
| 90 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.4058 | Yes |
| 91 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.3981 | Yes |
| 92 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 12345 | -0.183 | -0.3847 | Yes |
| 93 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 12366 | -0.185 | -0.3722 | Yes |
| 94 | EWSR1 | EWSR1 Entrez, Source | Ewing sarcoma breakpoint region 1 | 12393 | -0.187 | -0.3601 | Yes |
| 95 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 12438 | -0.192 | -0.3490 | Yes |
| 96 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 12583 | -0.209 | -0.3442 | Yes |
| 97 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12614 | -0.213 | -0.3305 | Yes |
| 98 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 12680 | -0.221 | -0.3188 | Yes |
| 99 | EIF2C2 | EIF2C2 Entrez, Source | eukaryotic translation initiation factor 2C, 2 | 12721 | -0.227 | -0.3047 | Yes |
| 100 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 12742 | -0.232 | -0.2888 | Yes |
| 101 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12748 | -0.232 | -0.2717 | Yes |
| 102 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 12783 | -0.238 | -0.2563 | Yes |
| 103 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 12827 | -0.248 | -0.2409 | Yes |
| 104 | NCL | NCL Entrez, Source | nucleolin | 12857 | -0.256 | -0.2239 | Yes |
| 105 | DAZAP1 | DAZAP1 Entrez, Source | DAZ associated protein 1 | 12861 | -0.256 | -0.2048 | Yes |
| 106 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12882 | -0.262 | -0.1867 | Yes |
| 107 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12914 | -0.270 | -0.1687 | Yes |
| 108 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.1500 | Yes |
| 109 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.1296 | Yes |
| 110 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 13030 | -0.302 | -0.1133 | Yes |
| 111 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 13050 | -0.307 | -0.0916 | Yes |
| 112 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 13080 | -0.318 | -0.0699 | Yes |
| 113 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 13297 | -0.589 | -0.0419 | Yes |
| 114 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13299 | -0.601 | 0.0033 | Yes |
