Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | V$USF_01 |
| Enrichment Score (ES) | -0.3952734 |
| Normalized Enrichment Score (NES) | -1.532826 |
| Nominal p-value | 0.004819277 |
| FDR q-value | 0.22347271 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 84 | 0.686 | 0.0399 | No |
| 2 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 98 | 0.666 | 0.0838 | No |
| 3 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 300 | 0.402 | 0.0958 | No |
| 4 | SLC38A2 | SLC38A2 Entrez, Source | solute carrier family 38, member 2 | 631 | 0.249 | 0.0876 | No |
| 5 | STX6 | STX6 Entrez, Source | syntaxin 6 | 766 | 0.222 | 0.0925 | No |
| 6 | SLC31A2 | SLC31A2 Entrez, Source | solute carrier family 31 (copper transporters), member 2 | 819 | 0.210 | 0.1027 | No |
| 7 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 926 | 0.191 | 0.1076 | No |
| 8 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 970 | 0.186 | 0.1169 | No |
| 9 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 1181 | 0.163 | 0.1120 | No |
| 10 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 1218 | 0.159 | 0.1200 | No |
| 11 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1266 | 0.154 | 0.1269 | No |
| 12 | NIT1 | NIT1 Entrez, Source | nitrilase 1 | 1271 | 0.153 | 0.1369 | No |
| 13 | TEF | TEF Entrez, Source | thyrotrophic embryonic factor | 1404 | 0.143 | 0.1366 | No |
| 14 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 1866 | 0.113 | 0.1094 | No |
| 15 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1870 | 0.113 | 0.1168 | No |
| 16 | KCNH4 | KCNH4 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 1993 | 0.108 | 0.1149 | No |
| 17 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 2030 | 0.106 | 0.1193 | No |
| 18 | MAX | MAX Entrez, Source | MYC associated factor X | 2495 | 0.088 | 0.0902 | No |
| 19 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 2507 | 0.088 | 0.0953 | No |
| 20 | BOK | BOK Entrez, Source | BCL2-related ovarian killer | 3556 | 0.056 | 0.0198 | No |
| 21 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 3675 | 0.053 | 0.0145 | No |
| 22 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 3779 | 0.051 | 0.0101 | No |
| 23 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 3920 | 0.047 | 0.0027 | No |
| 24 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 3964 | 0.045 | 0.0025 | No |
| 25 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 4337 | 0.037 | -0.0231 | No |
| 26 | GNAS | GNAS Entrez, Source | GNAS complex locus | 4431 | 0.035 | -0.0278 | No |
| 27 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 4644 | 0.031 | -0.0417 | No |
| 28 | SYT3 | SYT3 Entrez, Source | synaptotagmin III | 4986 | 0.024 | -0.0658 | No |
| 29 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 4992 | 0.024 | -0.0646 | No |
| 30 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4993 | 0.024 | -0.0630 | No |
| 31 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5193 | 0.020 | -0.0766 | No |
| 32 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 5213 | 0.020 | -0.0767 | No |
| 33 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5509 | 0.014 | -0.0980 | No |
| 34 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 5716 | 0.011 | -0.1129 | No |
| 35 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 5801 | 0.009 | -0.1186 | No |
| 36 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 5876 | 0.008 | -0.1237 | No |
| 37 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 6092 | 0.003 | -0.1397 | No |
| 38 | PER1 | PER1 Entrez, Source | period homolog 1 (Drosophila) | 6161 | 0.002 | -0.1447 | No |
| 39 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 6295 | -0.000 | -0.1547 | No |
| 40 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 6696 | -0.007 | -0.1845 | No |
| 41 | RAB3IL1 | RAB3IL1 Entrez, Source | RAB3A interacting protein (rabin3)-like 1 | 6749 | -0.008 | -0.1879 | No |
| 42 | ADAM10 | ADAM10 Entrez, Source | ADAM metallopeptidase domain 10 | 7189 | -0.016 | -0.2200 | No |
| 43 | SCYL1 | SCYL1 Entrez, Source | SCY1-like 1 (S. cerevisiae) | 7338 | -0.018 | -0.2299 | No |
| 44 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 7498 | -0.022 | -0.2405 | No |
| 45 | EIF3S10 | EIF3S10 Entrez, Source | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | 7771 | -0.027 | -0.2592 | No |
| 46 | SLC26A2 | SLC26A2 Entrez, Source | solute carrier family 26 (sulfate transporter), member 2 | 7843 | -0.028 | -0.2627 | No |
| 47 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 7908 | -0.029 | -0.2656 | No |
| 48 | OPRS1 | OPRS1 Entrez, Source | opioid receptor, sigma 1 | 7920 | -0.030 | -0.2644 | No |
| 49 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 8002 | -0.031 | -0.2684 | No |
| 50 | COMMD3 | COMMD3 Entrez, Source | COMM domain containing 3 | 8085 | -0.033 | -0.2724 | No |
| 51 | SLC12A6 | SLC12A6 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 6 | 8133 | -0.034 | -0.2736 | No |
| 52 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 8212 | -0.035 | -0.2771 | No |
| 53 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 8263 | -0.037 | -0.2784 | No |
| 54 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 8462 | -0.041 | -0.2906 | No |
| 55 | GGN | GGN Entrez, Source | gametogenetin | 8728 | -0.046 | -0.3076 | No |
| 56 | NEUROD1 | NEUROD1 Entrez, Source | neurogenic differentiation 1 | 8841 | -0.049 | -0.3128 | No |
| 57 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 9018 | -0.052 | -0.3225 | No |
| 58 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 9213 | -0.056 | -0.3334 | No |
| 59 | TESK2 | TESK2 Entrez, Source | testis-specific kinase 2 | 9339 | -0.059 | -0.3389 | No |
| 60 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 9447 | -0.062 | -0.3428 | No |
| 61 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 9465 | -0.062 | -0.3399 | No |
| 62 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 9594 | -0.065 | -0.3452 | No |
| 63 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 10054 | -0.078 | -0.3746 | No |
| 64 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10112 | -0.079 | -0.3736 | No |
| 65 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 10248 | -0.083 | -0.3782 | No |
| 66 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 10359 | -0.086 | -0.3807 | No |
| 67 | OPRD1 | OPRD1 Entrez, Source | opioid receptor, delta 1 | 10459 | -0.089 | -0.3821 | No |
| 68 | RAI14 | RAI14 Entrez, Source | retinoic acid induced 14 | 10469 | -0.089 | -0.3768 | No |
| 69 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 10474 | -0.089 | -0.3711 | No |
| 70 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10485 | -0.090 | -0.3658 | No |
| 71 | ATIC | ATIC Entrez, Source | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 10497 | -0.090 | -0.3605 | No |
| 72 | TOM1 | TOM1 Entrez, Source | target of myb1 (chicken) | 10506 | -0.090 | -0.3550 | No |
| 73 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 10893 | -0.105 | -0.3772 | No |
| 74 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10984 | -0.108 | -0.3767 | No |
| 75 | VPS16 | VPS16 Entrez, Source | vacuolar protein sorting 16 (yeast) | 11066 | -0.111 | -0.3754 | No |
| 76 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 11249 | -0.118 | -0.3812 | No |
| 77 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 11398 | -0.125 | -0.3839 | No |
| 78 | RAB24 | RAB24 Entrez, Source | RAB24, member RAS oncogene family | 11518 | -0.130 | -0.3842 | No |
| 79 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 11666 | -0.137 | -0.3861 | Yes |
| 80 | VPS33A | VPS33A Entrez, Source | vacuolar protein sorting 33 homolog A (S. cerevisiae) | 11733 | -0.140 | -0.3816 | Yes |
| 81 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 11829 | -0.146 | -0.3789 | Yes |
| 82 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 11907 | -0.150 | -0.3746 | Yes |
| 83 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 11929 | -0.152 | -0.3660 | Yes |
| 84 | HTF9C | HTF9C Entrez, Source | - | 11970 | -0.155 | -0.3585 | Yes |
| 85 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11989 | -0.156 | -0.3493 | Yes |
| 86 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 12002 | -0.158 | -0.3396 | Yes |
| 87 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 12007 | -0.158 | -0.3292 | Yes |
| 88 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 12048 | -0.161 | -0.3214 | Yes |
| 89 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12098 | -0.164 | -0.3141 | Yes |
| 90 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 12176 | -0.170 | -0.3085 | Yes |
| 91 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12198 | -0.171 | -0.2985 | Yes |
| 92 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 12244 | -0.175 | -0.2901 | Yes |
| 93 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12259 | -0.176 | -0.2793 | Yes |
| 94 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 12263 | -0.177 | -0.2676 | Yes |
| 95 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 12339 | -0.183 | -0.2609 | Yes |
| 96 | USP15 | USP15 Entrez, Source | ubiquitin specific peptidase 15 | 12366 | -0.185 | -0.2504 | Yes |
| 97 | GTF2A1 | GTF2A1 Entrez, Source | general transcription factor IIA, 1, 19/37kDa | 12822 | -0.246 | -0.2682 | Yes |
| 98 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 12823 | -0.247 | -0.2516 | Yes |
| 99 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 12882 | -0.262 | -0.2383 | Yes |
| 100 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12936 | -0.273 | -0.2239 | Yes |
| 101 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 12940 | -0.274 | -0.2056 | Yes |
| 102 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12945 | -0.275 | -0.1874 | Yes |
| 103 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 12959 | -0.279 | -0.1696 | Yes |
| 104 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12971 | -0.283 | -0.1513 | Yes |
| 105 | CUL5 | CUL5 Entrez, Source | cullin 5 | 13074 | -0.316 | -0.1377 | Yes |
| 106 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 13111 | -0.334 | -0.1179 | Yes |
| 107 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 13227 | -0.440 | -0.0970 | Yes |
| 108 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 13267 | -0.519 | -0.0649 | Yes |
| 109 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13269 | -0.522 | -0.0298 | Yes |
| 110 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 13271 | -0.523 | 0.0054 | Yes |
