Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | VEGF_MMMEC_3HRS_UP |
| Enrichment Score (ES) | 0.54848 |
| Normalized Enrichment Score (NES) | 1.7325858 |
| Nominal p-value | 0.005484461 |
| FDR q-value | 0.04511731 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD9 | CD9 Entrez, Source | CD9 molecule | 41 | 0.871 | 0.0991 | Yes |
| 2 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 56 | 0.784 | 0.1899 | Yes |
| 3 | MGP | MGP Entrez, Source | matrix Gla protein | 108 | 0.644 | 0.2615 | Yes |
| 4 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 167 | 0.536 | 0.3200 | Yes |
| 5 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 183 | 0.515 | 0.3792 | Yes |
| 6 | BGN | BGN Entrez, Source | biglycan | 241 | 0.450 | 0.4276 | Yes |
| 7 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 405 | 0.336 | 0.4547 | Yes |
| 8 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 474 | 0.294 | 0.4841 | Yes |
| 9 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 656 | 0.244 | 0.4991 | Yes |
| 10 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 746 | 0.228 | 0.5191 | Yes |
| 11 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 909 | 0.194 | 0.5297 | Yes |
| 12 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 1133 | 0.167 | 0.5325 | Yes |
| 13 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 1178 | 0.163 | 0.5483 | Yes |
| 14 | HEMGN | HEMGN Entrez, Source | hemogen | 1555 | 0.131 | 0.5353 | Yes |
| 15 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1785 | 0.118 | 0.5319 | Yes |
| 16 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1870 | 0.113 | 0.5388 | Yes |
| 17 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 2041 | 0.106 | 0.5385 | Yes |
| 18 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 2072 | 0.105 | 0.5485 | Yes |
| 19 | VWF | VWF Entrez, Source | von Willebrand factor | 2400 | 0.092 | 0.5346 | No |
| 20 | GALNT1 | GALNT1 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) | 3331 | 0.062 | 0.4719 | No |
| 21 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 3348 | 0.061 | 0.4779 | No |
| 22 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 3378 | 0.061 | 0.4828 | No |
| 23 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 3399 | 0.060 | 0.4884 | No |
| 24 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 3514 | 0.057 | 0.4865 | No |
| 25 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 3591 | 0.055 | 0.4873 | No |
| 26 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 3758 | 0.051 | 0.4807 | No |
| 27 | HCLS1 | HCLS1 Entrez, Source | hematopoietic cell-specific Lyn substrate 1 | 3872 | 0.048 | 0.4779 | No |
| 28 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 4357 | 0.037 | 0.4458 | No |
| 29 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 4442 | 0.035 | 0.4435 | No |
| 30 | CEACAM1 | CEACAM1 Entrez, Source | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 4467 | 0.035 | 0.4458 | No |
| 31 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 4938 | 0.025 | 0.4134 | No |
| 32 | ISL1 | ISL1 Entrez, Source | ISL1 transcription factor, LIM/homeodomain, (islet-1) | 5512 | 0.014 | 0.3719 | No |
| 33 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 5689 | 0.011 | 0.3600 | No |
| 34 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 6720 | -0.008 | 0.2834 | No |
| 35 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 6888 | -0.010 | 0.2721 | No |
| 36 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 7179 | -0.015 | 0.2520 | No |
| 37 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 7315 | -0.018 | 0.2440 | No |
| 38 | PRKCI | PRKCI Entrez, Source | protein kinase C, iota | 7723 | -0.026 | 0.2164 | No |
| 39 | GSTT1 | GSTT1 Entrez, Source | glutathione S-transferase theta 1 | 7971 | -0.031 | 0.2014 | No |
| 40 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 8172 | -0.035 | 0.1904 | No |
| 41 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 8718 | -0.046 | 0.1548 | No |
| 42 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 8929 | -0.050 | 0.1449 | No |
| 43 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 9382 | -0.060 | 0.1179 | No |
| 44 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10704 | -0.097 | 0.0299 | No |
| 45 | NDUFA1 | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 10713 | -0.098 | 0.0407 | No |
| 46 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 10771 | -0.100 | 0.0481 | No |
| 47 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 10780 | -0.100 | 0.0593 | No |
| 48 | SLC6A8 | SLC6A8 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 11242 | -0.118 | 0.0384 | No |
| 49 | RBX1 | RBX1 Entrez, Source | ring-box 1 | 11606 | -0.134 | 0.0267 | No |
| 50 | TRIM23 | TRIM23 Entrez, Source | tripartite motif-containing 23 | 12278 | -0.177 | -0.0030 | No |
| 51 | RALA | RALA Entrez, Source | v-ral simian leukemia viral oncogene homolog A (ras related) | 12488 | -0.197 | 0.0044 | No |
| 52 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12617 | -0.213 | 0.0198 | No |
| 53 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 13014 | -0.296 | 0.0247 | No |
