Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_24h.class.cls
#double_gel_8d_versus_double_gel_24h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_24h_repos
Upregulated in classdouble_gel_8d
GeneSetVEGF_MMMEC_ALL_UP
Enrichment Score (ES)0.6071244
Normalized Enrichment Score (NES)2.040503
Nominal p-value0.0
FDR q-value0.0029559692
FWER p-Value0.069
Table: GSEA Results Summary



Fig 1: Enrichment plot: VEGF_MMMEC_ALL_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 2121.2540.1047Yes
2CD9CD9
Entrez,  Source
CD9 molecule410.8710.1760Yes
3ANKRD1ANKRD1
Entrez,  Source
ankyrin repeat domain 1 (cardiac muscle)560.7840.2410Yes
4MGPMGP
Entrez,  Source
matrix Gla protein1080.6440.2914Yes
5RGS5RGS5
Entrez,  Source
regulator of G-protein signalling 51250.6160.3421Yes
6AQP7AQP7
Entrez,  Source
aquaporin 71670.5360.3842Yes
7VCAM1VCAM1
Entrez,  Source
vascular cell adhesion molecule 11830.5150.4264Yes
8FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 12030.4840.4658Yes
9BGNBGN
Entrez,  Source
biglycan2410.4500.5009Yes
10CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 24050.3360.5169Yes
11CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)4740.2940.5366Yes
12IGFBP3IGFBP3
Entrez,  Source
insulin-like growth factor binding protein 35330.2740.5553Yes
13FOXO1AFOXO1A
Entrez,  Source
forkhead box O1A (rhabdomyosarcoma)6560.2440.5666Yes
14IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 37460.2280.5791Yes
15SULT1E1SULT1E1
Entrez,  Source
sulfotransferase family 1E, estrogen-preferring, member 19090.1940.5833Yes
16DIRC2DIRC2
Entrez,  Source
disrupted in renal carcinoma 29260.1910.5982Yes
17HEXAHEXA
Entrez,  Source
hexosaminidase A (alpha polypeptide)11330.1670.5967Yes
18FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 111780.1630.6071Yes
19HEMGNHEMGN
Entrez,  Source
hemogen15550.1310.5898No
20NR4A1NR4A1
Entrez,  Source
nuclear receptor subfamily 4, group A, member 117850.1180.5825No
21BMP4BMP4
Entrez,  Source
bone morphogenetic protein 418700.1130.5857No
22TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 120410.1060.5818No
23RHOBRHOB
Entrez,  Source
ras homolog gene family, member B20720.1050.5884No
24SGCESGCE
Entrez,  Source
sarcoglycan, epsilon22740.0960.5814No
25VWFVWF
Entrez,  Source
von Willebrand factor24000.0920.5797No
26GALNT1GALNT1
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)33310.0620.5148No
27BMP6BMP6
Entrez,  Source
bone morphogenetic protein 633480.0610.5188No
28EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 133780.0610.5217No
29ESR1ESR1
Entrez,  Source
estrogen receptor 133990.0600.5253No
30SP3SP3
Entrez,  Source
Sp3 transcription factor35140.0570.5215No
31TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 235910.0550.5204No
32PIRPIR
Entrez,  Source
pirin (iron-binding nuclear protein)37580.0510.5122No
33UBDUBD
Entrez,  Source
ubiquitin D37830.0500.5146No
34SDC4SDC4
Entrez,  Source
syndecan 4 (amphiglycan, ryudocan)37990.0500.5177No
35HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 138720.0480.5164No
36NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)40250.0440.5086No
37PVALBPVALB
Entrez,  Source
parvalbumin43380.0370.4882No
38HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 243570.0370.4899No
39CCL7CCL7
Entrez,  Source
chemokine (C-C motif) ligand 744090.0360.4891No
40KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)44420.0350.4896No
41CEACAM1CEACAM1
Entrez,  Source
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)44670.0350.4907No
42THY1THY1
Entrez,  Source
Thy-1 cell surface antigen44780.0340.4929No
43MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)49380.0250.4604No
44HTR2BHTR2B
Entrez,  Source
5-hydroxytryptamine (serotonin) receptor 2B50100.0240.4571No
45ISL1ISL1
Entrez,  Source
ISL1 transcription factor, LIM/homeodomain, (islet-1)55120.0140.4205No
46MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)55400.0140.4197No
47GJA4GJA4
Entrez,  Source
gap junction protein, alpha 4, 37kDa (connexin 37)56890.0110.4095No
48ADORA2BADORA2B
Entrez,  Source
adenosine A2b receptor57720.0100.4041No
49OXTROXTR
Entrez,  Source
oxytocin receptor59400.0060.3920No
50ADD2ADD2
Entrez,  Source
adducin 2 (beta)6720-0.0080.3340No
51DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 16888-0.0100.3223No
52PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)7179-0.0150.3017No
53ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)7315-0.0180.2931No
54PRKCIPRKCI
Entrez,  Source
protein kinase C, iota7723-0.0260.2646No
55CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)7897-0.0290.2540No
56GSTT1GSTT1
Entrez,  Source
glutathione S-transferase theta 17971-0.0310.2511No
57NAGKNAGK
Entrez,  Source
N-acetylglucosamine kinase8172-0.0350.2389No
58PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein8718-0.0460.2017No
59ANGPT2ANGPT2
Entrez,  Source
angiopoietin 28929-0.0500.1901No
60UNGUNG
Entrez,  Source
uracil-DNA glycosylase9382-0.0600.1611No
61FAPFAP
Entrez,  Source
fibroblast activation protein, alpha10470-0.0890.0868No
62RANGAP1RANGAP1
Entrez,  Source
Ran GTPase activating protein 110704-0.0970.0774No
63NDUFA1NDUFA1
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa10713-0.0980.0850No
64MRPL19MRPL19
Entrez,  Source
mitochondrial ribosomal protein L1910771-0.1000.0891No
65EMR1EMR1
Entrez,  Source
egf-like module containing, mucin-like, hormone receptor-like 110780-0.1000.0970No
66SLC6A8SLC6A8
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, creatine), member 811242-0.1180.0721No
67RBX1RBX1
Entrez,  Source
ring-box 111606-0.1340.0560No
68TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2312278-0.1770.0204No
69RALARALA
Entrez,  Source
v-ral simian leukemia viral oncogene homolog A (ras related)12488-0.1970.0213No
70GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12617-0.2130.0296No
71PIM1PIM1
Entrez,  Source
pim-1 oncogene13014-0.2960.0247No
Table: GSEA details [plain text format]



Fig 2: VEGF_MMMEC_ALL_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: VEGF_MMMEC_ALL_UP: Random ES distribution   
Gene set null distribution of ES for VEGF_MMMEC_ALL_UP