Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_24h |
| GeneSet | WIELAND_HEPATITIS_B_INDUCED |
| Enrichment Score (ES) | -0.4583191 |
| Normalized Enrichment Score (NES) | -1.5703048 |
| Nominal p-value | 0.009756098 |
| FDR q-value | 0.18658103 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HLA-DMA | HLA-DMA Entrez, Source | major histocompatibility complex, class II, DM alpha | 33 | 0.905 | 0.0794 | No |
| 2 | UCP2 | UCP2 Entrez, Source | uncoupling protein 2 (mitochondrial, proton carrier) | 443 | 0.313 | 0.0769 | No |
| 3 | HLA-DMB | HLA-DMB Entrez, Source | major histocompatibility complex, class II, DM beta | 483 | 0.292 | 0.1003 | No |
| 4 | CD48 | CD48 Entrez, Source | CD48 molecule | 611 | 0.256 | 0.1139 | No |
| 5 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 786 | 0.217 | 0.1204 | No |
| 6 | IGSF6 | IGSF6 Entrez, Source | immunoglobulin superfamily, member 6 | 872 | 0.199 | 0.1321 | No |
| 7 | TYROBP | TYROBP Entrez, Source | TYRO protein tyrosine kinase binding protein | 965 | 0.187 | 0.1420 | No |
| 8 | LPXN | LPXN Entrez, Source | leupaxin | 979 | 0.185 | 0.1578 | No |
| 9 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 1866 | 0.113 | 0.1013 | No |
| 10 | IL10RA | IL10RA Entrez, Source | interleukin 10 receptor, alpha | 2351 | 0.093 | 0.0733 | No |
| 11 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 2353 | 0.093 | 0.0817 | No |
| 12 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 2541 | 0.086 | 0.0754 | No |
| 13 | CD53 | CD53 Entrez, Source | CD53 molecule | 2932 | 0.073 | 0.0527 | No |
| 14 | GZMK | GZMK Entrez, Source | granzyme K (granzyme 3; tryptase II) | 2942 | 0.073 | 0.0586 | No |
| 15 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 3128 | 0.068 | 0.0508 | No |
| 16 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 3438 | 0.060 | 0.0329 | No |
| 17 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 3660 | 0.053 | 0.0211 | No |
| 18 | RAB27A | RAB27A Entrez, Source | RAB27A, member RAS oncogene family | 3739 | 0.051 | 0.0198 | No |
| 19 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 3767 | 0.051 | 0.0224 | No |
| 20 | CD38 | CD38 Entrez, Source | CD38 molecule | 4439 | 0.035 | -0.0250 | No |
| 21 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 4454 | 0.035 | -0.0229 | No |
| 22 | CTSC | CTSC Entrez, Source | cathepsin C | 4468 | 0.035 | -0.0207 | No |
| 23 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 4488 | 0.034 | -0.0191 | No |
| 24 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 4630 | 0.031 | -0.0268 | No |
| 25 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 4875 | 0.027 | -0.0428 | No |
| 26 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 5264 | 0.019 | -0.0703 | No |
| 27 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 5827 | 0.009 | -0.1118 | No |
| 28 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 6381 | -0.001 | -0.1533 | No |
| 29 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 6393 | -0.002 | -0.1540 | No |
| 30 | B2M | B2M Entrez, Source | beta-2-microglobulin | 7066 | -0.014 | -0.2034 | No |
| 31 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 8284 | -0.037 | -0.2916 | No |
| 32 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 8369 | -0.039 | -0.2944 | No |
| 33 | PSMB10 | PSMB10 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 10 | 8678 | -0.045 | -0.3136 | No |
| 34 | GIMAP5 | GIMAP5 Entrez, Source | GTPase, IMAP family member 5 | 8827 | -0.048 | -0.3203 | No |
| 35 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 9675 | -0.067 | -0.3780 | No |
| 36 | CD3D | CD3D Entrez, Source | CD3d molecule, delta (CD3-TCR complex) | 9702 | -0.068 | -0.3738 | No |
| 37 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 10002 | -0.077 | -0.3894 | No |
| 38 | EMR1 | EMR1 Entrez, Source | egf-like module containing, mucin-like, hormone receptor-like 1 | 10780 | -0.100 | -0.4389 | No |
| 39 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 10958 | -0.107 | -0.4425 | No |
| 40 | CTSB | CTSB Entrez, Source | cathepsin B | 11060 | -0.110 | -0.4401 | No |
| 41 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 11180 | -0.115 | -0.4386 | No |
| 42 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 11382 | -0.124 | -0.4426 | No |
| 43 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 11592 | -0.133 | -0.4463 | Yes |
| 44 | GM2A | GM2A Entrez, Source | GM2 ganglioside activator | 11721 | -0.139 | -0.4433 | Yes |
| 45 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 11883 | -0.149 | -0.4419 | Yes |
| 46 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 11894 | -0.150 | -0.4291 | Yes |
| 47 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 11943 | -0.153 | -0.4189 | Yes |
| 48 | WARS | WARS Entrez, Source | tryptophanyl-tRNA synthetase | 12088 | -0.163 | -0.4150 | Yes |
| 49 | TAPBP | TAPBP Entrez, Source | TAP binding protein (tapasin) | 12132 | -0.167 | -0.4031 | Yes |
| 50 | AURKA | AURKA Entrez, Source | aurora kinase A | 12238 | -0.175 | -0.3953 | Yes |
| 51 | PSMB9 | PSMB9 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 12678 | -0.221 | -0.4083 | Yes |
| 52 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 12797 | -0.241 | -0.3954 | Yes |
| 53 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 12851 | -0.254 | -0.3764 | Yes |
| 54 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12914 | -0.270 | -0.3567 | Yes |
| 55 | CD68 | CD68 Entrez, Source | CD68 molecule | 13210 | -0.414 | -0.3415 | Yes |
| 56 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13288 | -0.553 | -0.2972 | Yes |
| 57 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13307 | -0.629 | -0.2417 | Yes |
| 58 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13322 | -0.789 | -0.1714 | Yes |
| 59 | CD5L | CD5L Entrez, Source | CD5 molecule-like | 13324 | -0.805 | -0.0986 | Yes |
| 60 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 13337 | -1.105 | 0.0004 | Yes |
