Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_24h.class.cls #double_gel_8d_versus_double_gel_24h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_24h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ZHAN_MULTIPLE_MYELOMA_VS_NORMAL_DN |
| Enrichment Score (ES) | 0.7395036 |
| Normalized Enrichment Score (NES) | 2.12773 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0011392061 |
| FWER p-Value | 0.011 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12 | 1.254 | 0.2090 | Yes |
| 2 | CD24 | CD24 Entrez, Source | CD24 molecule | 66 | 0.745 | 0.3298 | Yes |
| 3 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 103 | 0.659 | 0.4374 | Yes |
| 4 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 183 | 0.515 | 0.5176 | Yes |
| 5 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 185 | 0.510 | 0.6029 | Yes |
| 6 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 214 | 0.474 | 0.6801 | Yes |
| 7 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 364 | 0.357 | 0.7287 | Yes |
| 8 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 746 | 0.228 | 0.7382 | Yes |
| 9 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 1232 | 0.158 | 0.7282 | Yes |
| 10 | CTSH | CTSH Entrez, Source | cathepsin H | 1401 | 0.143 | 0.7395 | Yes |
| 11 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 2628 | 0.083 | 0.6613 | No |
| 12 | HNMT | HNMT Entrez, Source | histamine N-methyltransferase | 2986 | 0.072 | 0.6464 | No |
| 13 | PYGL | PYGL Entrez, Source | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 3567 | 0.056 | 0.6122 | No |
| 14 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 3776 | 0.051 | 0.6050 | No |
| 15 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 4022 | 0.044 | 0.5940 | No |
| 16 | LST1 | LST1 Entrez, Source | leukocyte specific transcript 1 | 4729 | 0.030 | 0.5459 | No |
| 17 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 4951 | 0.025 | 0.5335 | No |
| 18 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 5694 | 0.011 | 0.4797 | No |
| 19 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 5704 | 0.011 | 0.4808 | No |
| 20 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 6299 | -0.000 | 0.4362 | No |
| 21 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 6435 | -0.002 | 0.4264 | No |
| 22 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 6461 | -0.003 | 0.4250 | No |
| 23 | SYK | SYK Entrez, Source | spleen tyrosine kinase | 7042 | -0.013 | 0.3837 | No |
| 24 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 8582 | -0.043 | 0.2753 | No |
| 25 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 8638 | -0.044 | 0.2785 | No |
| 26 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 10160 | -0.081 | 0.1778 | No |
| 27 | CD99 | CD99 Entrez, Source | CD99 molecule | 10623 | -0.094 | 0.1589 | No |
| 28 | HHEX | HHEX Entrez, Source | homeobox, hematopoietically expressed | 10765 | -0.099 | 0.1650 | No |
| 29 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 12188 | -0.170 | 0.0867 | No |
