Details for gene set ALCALAY_AML_NPMC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	ALCALAY_AML_NPMC_DN
Enrichment Score (ES)	0.5024176
Normalized Enrichment Score (NES)	1.7998079
Nominal p-value	0.0
FDR q-value	0.025666272
FWER p-Value	0.971

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IGFBP7	IGFBP7 Entrez, Source	insulin-like growth factor binding protein 7	2	1.254	0.1141	Yes
2	HLA-DMA	HLA-DMA Entrez, Source	major histocompatibility complex, class II, DM alpha	32	0.725	0.1780	Yes
3	IL1R2	IL1R2 Entrez, Source	interleukin 1 receptor, type II	89	0.531	0.2221	Yes
4	IFITM2	IFITM2 Entrez, Source	interferon induced transmembrane protein 2 (1-8D)	254	0.339	0.2407	Yes
5	SPARC	SPARC Entrez, Source	secreted protein, acidic, cysteine-rich (osteonectin)	317	0.293	0.2627	Yes
6	CD48	CD48 Entrez, Source	CD48 molecule	352	0.281	0.2857	Yes
7	RGS10	RGS10 Entrez, Source	regulator of G-protein signalling 10	370	0.272	0.3093	Yes
8	PXMP2	PXMP2 Entrez, Source	peroxisomal membrane protein 2, 22kDa	408	0.257	0.3298	Yes
9	ACAA2	ACAA2 Entrez, Source	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	470	0.238	0.3469	Yes
10	GSN	GSN Entrez, Source	gelsolin (amyloidosis, Finnish type)	483	0.233	0.3672	Yes
11	ITM2C	ITM2C Entrez, Source	integral membrane protein 2C	491	0.231	0.3877	Yes
12	PROM1	PROM1 Entrez, Source	prominin 1	530	0.220	0.4049	Yes
13	HADH	HADH Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase	566	0.213	0.4216	Yes
14	PLAGL1	PLAGL1 Entrez, Source	pleiomorphic adenoma gene-like 1	576	0.211	0.4401	Yes
15	CD96	CD96 Entrez, Source	CD96 molecule	677	0.189	0.4498	Yes
16	ITGA9	ITGA9 Entrez, Source	integrin, alpha 9	767	0.175	0.4590	Yes
17	ACAT1	ACAT1 Entrez, Source	acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)	809	0.168	0.4712	Yes
18	TRAK2	TRAK2 Entrez, Source	trafficking protein, kinesin binding 2	882	0.158	0.4802	Yes
19	KYNU	KYNU Entrez, Source	kynureninase (L-kynurenine hydrolase)	934	0.153	0.4903	Yes
20	PBX2	PBX2 Entrez, Source	pre-B-cell leukemia transcription factor 2	956	0.151	0.5024	Yes
21	MLLT3	MLLT3 Entrez, Source	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	1443	0.111	0.4759	No
22	B4GALT6	B4GALT6 Entrez, Source	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6	1451	0.111	0.4854	No
23	KIF2C	KIF2C Entrez, Source	kinesin family member 2C	1773	0.094	0.4698	No
24	GNB5	GNB5 Entrez, Source	guanine nucleotide binding protein (G protein), beta 5	1878	0.089	0.4701	No
25	HPCAL1	HPCAL1 Entrez, Source	hippocalcin-like 1	2224	0.076	0.4510	No
26	INPP4B	INPP4B Entrez, Source	inositol polyphosphate-4-phosphatase, type II, 105kDa	2455	0.069	0.4399	No
27	FAAH	FAAH Entrez, Source	fatty acid amide hydrolase	2484	0.069	0.4440	No
28	SEPT9	SEPT9 Entrez, Source	septin 9	2498	0.068	0.4493	No
29	IL2RG	IL2RG Entrez, Source	interleukin 2 receptor, gamma (severe combined immunodeficiency)	2582	0.065	0.4489	No
30	SERPINI1	SERPINI1 Entrez, Source	serpin peptidase inhibitor, clade I (neuroserpin), member 1	2621	0.064	0.4519	No
31	FKBP1B	FKBP1B Entrez, Source	FK506 binding protein 1B, 12.6 kDa	2776	0.061	0.4458	No
32	PTTG1	PTTG1 Entrez, Source	pituitary tumor-transforming 1	2806	0.060	0.4491	No
33	BAALC	BAALC Entrez, Source	brain and acute leukemia, cytoplasmic	2819	0.060	0.4536	No
34	STOM	STOM Entrez, Source	stomatin	3184	0.050	0.4307	No
35	PIP5K1B	PIP5K1B Entrez, Source	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	3423	0.045	0.4168	No
36	ANK1	ANK1 Entrez, Source	ankyrin 1, erythrocytic	3656	0.040	0.4029	No
37	HMMR	HMMR Entrez, Source	hyaluronan-mediated motility receptor (RHAMM)	3845	0.036	0.3920	No
38	CD69	CD69 Entrez, Source	CD69 molecule	4095	0.031	0.3760	No
39	TRH	TRH Entrez, Source	thyrotropin-releasing hormone	4399	0.025	0.3554	No
40	RPS6KA2	RPS6KA2 Entrez, Source	ribosomal protein S6 kinase, 90kDa, polypeptide 2	4460	0.024	0.3531	No
41	WASF1	WASF1 Entrez, Source	WAS protein family, member 1	4524	0.023	0.3504	No
42	SERPINF1	SERPINF1 Entrez, Source	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1	4697	0.020	0.3393	No
43	INSL3	INSL3 Entrez, Source	insulin-like 3 (Leydig cell)	4741	0.019	0.3378	No
44	HMGN3	HMGN3 Entrez, Source	high mobility group nucleosomal binding domain 3	5116	0.013	0.3108	No
45	TMEM106C	TMEM106C Entrez, Source	transmembrane protein 106C	5202	0.012	0.3054	No
46	TNFRSF14	TNFRSF14 Entrez, Source	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	5269	0.011	0.3014	No
47	CCNF	CCNF Entrez, Source	cyclin F	5366	0.009	0.2950	No
48	FOXM1	FOXM1 Entrez, Source	forkhead box M1	5399	0.009	0.2934	No
49	GNG7	GNG7 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 7	5497	0.007	0.2867	No
50	TUBG1	TUBG1 Entrez, Source	tubulin, gamma 1	5540	0.007	0.2842	No
51	ASNA1	ASNA1 Entrez, Source	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	5871	0.002	0.2594	No
52	KIF4A	KIF4A Entrez, Source	kinesin family member 4A	6014	-0.000	0.2487	No
53	SLC1A4	SLC1A4 Entrez, Source	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	6096	-0.002	0.2428	No
54	CRHBP	CRHBP Entrez, Source	corticotropin releasing hormone binding protein	6512	-0.008	0.2122	No
55	KCNIP2	KCNIP2 Entrez, Source	Kv channel interacting protein 2	6562	-0.009	0.2092	No
56	NINJ2	NINJ2 Entrez, Source	ninjurin 2	6616	-0.009	0.2061	No
57	CCNB1	CCNB1 Entrez, Source	cyclin B1	6785	-0.012	0.1945	No
58	EVL	EVL Entrez, Source	Enah/Vasp-like	6806	-0.012	0.1941	No
59	CIITA	CIITA Entrez, Source	class II, major histocompatibility complex, transactivator	6886	-0.013	0.1894	No
60	CDKN2C	CDKN2C Entrez, Source	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	7011	-0.015	0.1814	No
61	BIRC5	BIRC5 Entrez, Source	baculoviral IAP repeat-containing 5 (survivin)	7015	-0.015	0.1825	No
62	CORO2A	CORO2A Entrez, Source	coronin, actin binding protein, 2A	7122	-0.017	0.1761	No
63	CD200	CD200 Entrez, Source	CD200 molecule	7585	-0.024	0.1434	No
64	OGG1	OGG1 Entrez, Source	8-oxoguanine DNA glycosylase	8478	-0.039	0.0796	No
65	EGFL7	EGFL7 Entrez, Source	EGF-like-domain, multiple 7	8671	-0.041	0.0689	No
66	CHEK1	CHEK1 Entrez, Source	CHK1 checkpoint homolog (S. pombe)	8812	-0.044	0.0623	No
67	S100B	S100B Entrez, Source	S100 calcium binding protein B	8923	-0.046	0.0582	No
68	CCNA2	CCNA2 Entrez, Source	cyclin A2	8927	-0.046	0.0622	No
69	MECR	MECR Entrez, Source	mitochondrial trans-2-enoyl-CoA reductase	9194	-0.050	0.0467	No
70	CDKN3	CDKN3 Entrez, Source	cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)	9384	-0.054	0.0373	No
71	SRD5A1	SRD5A1 Entrez, Source	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	9458	-0.055	0.0369	No
72	KIFC1	KIFC1 Entrez, Source	kinesin family member C1	9575	-0.057	0.0333	No
73	RAD23B	RAD23B Entrez, Source	RAD23 homolog B (S. cerevisiae)	9740	-0.061	0.0265	No
74	HGF	HGF Entrez, Source	hepatocyte growth factor (hepapoietin A; scatter factor)	9857	-0.063	0.0235	No
75	CD38	CD38 Entrez, Source	CD38 molecule	9966	-0.066	0.0213	No
76	POU4F1	POU4F1 Entrez, Source	POU domain, class 4, transcription factor 1	10099	-0.068	0.0176	No
77	GAMT	GAMT Entrez, Source	guanidinoacetate N-methyltransferase	10494	-0.078	-0.0051	No
78	POLD1	POLD1 Entrez, Source	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	11062	-0.092	-0.0395	No
79	HAAO	HAAO Entrez, Source	3-hydroxyanthranilate 3,4-dioxygenase	11121	-0.094	-0.0353	No
80	MTHFD1	MTHFD1 Entrez, Source	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	11221	-0.096	-0.0340	No
81	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	11386	-0.102	-0.0372	No
82	SYNGR1	SYNGR1 Entrez, Source	synaptogyrin 1	11408	-0.103	-0.0294	No
83	DHRS3	DHRS3 Entrez, Source	dehydrogenase/reductase (SDR family) member 3	11541	-0.107	-0.0296	No
84	HNRPD	HNRPD Entrez, Source	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	11613	-0.110	-0.0250	No
85	RHD	RHD Entrez, Source	Rh blood group, D antigen	11838	-0.119	-0.0311	No
86	CCNB2	CCNB2 Entrez, Source	cyclin B2	12025	-0.128	-0.0335	No
87	ARL2	ARL2 Entrez, Source	ADP-ribosylation factor-like 2	12040	-0.128	-0.0228	No
88	NUP210	NUP210 Entrez, Source	nucleoporin 210kDa	12052	-0.129	-0.0119	No
89	NPR3	NPR3 Entrez, Source	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	12092	-0.131	-0.0029	No
90	TYMS	TYMS Entrez, Source	thymidylate synthetase	12217	-0.137	0.0003	No
91	CDC20	CDC20 Entrez, Source	CDC20 cell division cycle 20 homolog (S. cerevisiae)	12218	-0.137	0.0128	No
92	DUT	DUT Entrez, Source	dUTP pyrophosphatase	12414	-0.149	0.0116	No
93	ABCG2	ABCG2 Entrez, Source	ATP-binding cassette, sub-family G (WHITE), member 2	12709	-0.174	0.0053	No
94	RBM3	RBM3 Entrez, Source	RNA binding motif (RNP1, RRM) protein 3	12930	-0.204	0.0073	No
95	HOMER2	HOMER2 Entrez, Source	homer homolog 2 (Drosophila)	13128	-0.260	0.0162	No