Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | BILE_ACID_BIOSYNTHESIS |
| Enrichment Score (ES) | 0.73372126 |
| Normalized Enrichment Score (NES) | 1.9944974 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.004915552 |
| FWER p-Value | 0.22 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 74 | 0.567 | 0.2339 | Yes |
| 2 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 394 | 0.263 | 0.3210 | Yes |
| 3 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 470 | 0.238 | 0.4157 | Yes |
| 4 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 517 | 0.223 | 0.5066 | Yes |
| 5 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 739 | 0.178 | 0.5652 | Yes |
| 6 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 798 | 0.170 | 0.6325 | Yes |
| 7 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 906 | 0.156 | 0.6903 | Yes |
| 8 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 1096 | 0.137 | 0.7337 | Yes |
| 9 | CEL | CEL Entrez, Source | carboxyl ester lipase (bile salt-stimulated lipase) | 2522 | 0.067 | 0.6551 | No |
| 10 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 3072 | 0.052 | 0.6360 | No |
| 11 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 3245 | 0.048 | 0.6435 | No |
| 12 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 3254 | 0.048 | 0.6633 | No |
| 13 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 3480 | 0.043 | 0.6647 | No |
| 14 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 5260 | 0.011 | 0.5357 | No |
| 15 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 5740 | 0.004 | 0.5013 | No |
| 16 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6171 | -0.003 | 0.4701 | No |
| 17 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 6362 | -0.006 | 0.4582 | No |
| 18 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 7402 | -0.021 | 0.3891 | No |
| 19 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 8528 | -0.039 | 0.3212 | No |
| 20 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 8536 | -0.039 | 0.3373 | No |
| 21 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 9458 | -0.055 | 0.2915 | No |
