Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetBOQUEST_CD31PLUS_VS_CD31MINUS_UP
Enrichment Score (ES)0.4836616
Normalized Enrichment Score (NES)2.0459166
Nominal p-value0.0
FDR q-value0.0025709972
FWER p-Value0.095
Table: GSEA Results Summary



Fig 1: Enrichment plot: BOQUEST_CD31PLUS_VS_CD31MINUS_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1MAP3K8MAP3K8
Entrez,  Source
mitogen-activated protein kinase kinase kinase 8120.8780.0172Yes
2RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa250.7710.0322Yes
3HLA-DMAHLA-DMA
Entrez,  Source
major histocompatibility complex, class II, DM alpha320.7250.0467Yes
4MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)430.6750.0598Yes
5LPLLPL
Entrez,  Source
lipoprotein lipase450.6710.0736Yes
6MGPMGP
Entrez,  Source
matrix Gla protein520.6340.0862Yes
7SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1560.6280.0989Yes
8RAPGEF4RAPGEF4
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 4660.6000.1106Yes
9PDK4PDK4
Entrez,  Source
pyruvate dehydrogenase kinase, isozyme 4840.5490.1206Yes
10EGR2EGR2
Entrez,  Source
early growth response 2 (Krox-20 homolog, Drosophila)870.5370.1315Yes
11RNASE1RNASE1
Entrez,  Source
ribonuclease, RNase A family, 1 (pancreatic)940.5290.1420Yes
12RGS16RGS16
Entrez,  Source
regulator of G-protein signalling 161030.5050.1518Yes
13OMDOMD
Entrez,  Source
osteomodulin1090.4900.1615Yes
14TNFAIP6TNFAIP6
Entrez,  Source
tumor necrosis factor, alpha-induced protein 61160.4830.1710Yes
15GPR64GPR64
Entrez,  Source
G protein-coupled receptor 641310.4660.1795Yes
16CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 21380.4580.1885Yes
17AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 11390.4570.1979Yes
18SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21400.4550.2073Yes
19CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 21450.4520.2164Yes
20APOC1APOC1
Entrez,  Source
apolipoprotein C-I1510.4450.2251Yes
21LOXLOX
Entrez,  Source
lysyl oxidase1540.4410.2341Yes
22PRKAR2BPRKAR2B
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, beta1600.4340.2427Yes
23BMP2BMP2
Entrez,  Source
bone morphogenetic protein 21640.4300.2513Yes
24PGCPPGCP
Entrez,  Source
-1830.4040.2582Yes
25ABCG1ABCG1
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 11870.4000.2663Yes
26GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)1990.3910.2735Yes
27PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein2040.3830.2811Yes
28CFDCFD
Entrez,  Source
complement factor D (adipsin)2280.3650.2868Yes
29SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 12310.3640.2942Yes
30PLA1APLA1A
Entrez,  Source
phospholipase A1 member A2360.3550.3012Yes
31FMO3FMO3
Entrez,  Source
flavin containing monooxygenase 32810.3220.3044Yes
32CD9CD9
Entrez,  Source
CD9 molecule2830.3200.3110Yes
33TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32860.3170.3173Yes
34ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)2980.3100.3229Yes
35CLIC2CLIC2
Entrez,  Source
chloride intracellular channel 23040.3040.3288Yes
36ATF3ATF3
Entrez,  Source
activating transcription factor 33100.2990.3346Yes
37CBSCBS
Entrez,  Source
cystathionine-beta-synthase3130.2970.3406Yes
38TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)3160.2940.3465Yes
39PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D3300.2900.3514Yes
40SLC5A3SLC5A3
Entrez,  Source
solute carrier family 5 (inositol transporters), member 33330.2890.3572Yes
41RAPGEF5RAPGEF5
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 53840.2670.3589Yes
42GDF15GDF15
Entrez,  Source
growth differentiation factor 153850.2670.3644Yes
43PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)4020.2580.3685Yes
44TMEM176BTMEM176B
Entrez,  Source
transmembrane protein 176B4030.2580.3738Yes
45CCNL1CCNL1
Entrez,  Source
cyclin L14050.2570.3790Yes
46FOXO1AFOXO1A
Entrez,  Source
forkhead box O1A (rhabdomyosarcoma)4110.2560.3839Yes
47KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)4170.2540.3888Yes
48DDAH1DDAH1
Entrez,  Source
dimethylarginine dimethylaminohydrolase 14210.2540.3938Yes
49RAMP3RAMP3
Entrez,  Source
receptor (calcitonin) activity modifying protein 34290.2510.3984Yes
50RGS4RGS4
Entrez,  Source
regulator of G-protein signalling 44540.2440.4016Yes
51THBDTHBD
Entrez,  Source
thrombomodulin4740.2360.4050Yes
52GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4830.2330.4092Yes
53ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 44930.2300.4133Yes
54RGS5RGS5
Entrez,  Source
regulator of G-protein signalling 55130.2240.4164Yes
55VCAM1VCAM1
Entrez,  Source
vascular cell adhesion molecule 15160.2230.4209Yes
56CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator5230.2220.4250Yes
57SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 15380.2190.4284Yes
58ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule5390.2190.4329Yes
59SCARB1SCARB1
Entrez,  Source
scavenger receptor class B, member 16200.2030.4309Yes
60FLI1FLI1
Entrez,  Source
Friend leukemia virus integration 16270.2020.4346Yes
61STX11STX11
Entrez,  Source
syntaxin 116990.1860.4330Yes
62RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7090.1840.4361Yes
63NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha7540.1760.4363Yes
64EGR1EGR1
Entrez,  Source
early growth response 17560.1760.4399Yes
65IL6RIL6R
Entrez,  Source
interleukin 6 receptor7610.1760.4432Yes
66CD320CD320
Entrez,  Source
CD320 molecule7700.1740.4462Yes
67EMP2EMP2
Entrez,  Source
epithelial membrane protein 27730.1740.4496Yes
68SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)7840.1720.4524Yes
69FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)7890.1720.4556Yes
70CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 18370.1640.4554Yes
71JUNBJUNB
Entrez,  Source
jun B proto-oncogene8610.1610.4569Yes
72BTG2BTG2
Entrez,  Source
BTG family, member 28800.1590.4588Yes
73FABP4FABP4
Entrez,  Source
fatty acid binding protein 4, adipocyte8840.1580.4618Yes
74PALMDPALMD
Entrez,  Source
palmdelphin9860.1480.4571Yes
75KLF9KLF9
Entrez,  Source
Kruppel-like factor 99980.1470.4593Yes
76IL3RAIL3RA
Entrez,  Source
interleukin 3 receptor, alpha (low affinity)10130.1460.4612Yes
77CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)10410.1420.4621Yes
78SLC38A1SLC38A1
Entrez,  Source
solute carrier family 38, member 111090.1350.4597Yes
79AGC1AGC1
Entrez,  Source
aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)11180.1350.4619Yes
80ANXA3ANXA3
Entrez,  Source
annexin A311700.1310.4606Yes
81GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta12100.1270.4602Yes
82KLHL24KLHL24
Entrez,  Source
kelch-like 24 (Drosophila)12150.1260.4625Yes
83PHLDA1PHLDA1
Entrez,  Source
pleckstrin homology-like domain, family A, member 112210.1260.4648Yes
84ICA1ICA1
Entrez,  Source
islet cell autoantigen 1, 69kDa12230.1260.4673Yes
85CD302CD302
Entrez,  Source
CD302 molecule12330.1250.4691Yes
86PSCD1PSCD1
Entrez,  Source
pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)12370.1250.4715Yes
87TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 212410.1240.4738Yes
88ZFP36ZFP36
Entrez,  Source
zinc finger protein 36, C3H type, homolog (mouse)12600.1230.4750Yes
89DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112610.1230.4775Yes
90CLK1CLK1
Entrez,  Source
CDC-like kinase 112620.1230.4800Yes
91KLF6KLF6
Entrez,  Source
Kruppel-like factor 612860.1210.4808Yes
92TSPAN8TSPAN8
Entrez,  Source
tetraspanin 813110.1190.4814Yes
93SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 513140.1190.4837Yes
94TSPAN12TSPAN12
Entrez,  Source
tetraspanin 1214310.1120.4770No
95PER2PER2
Entrez,  Source
period homolog 2 (Drosophila)14540.1100.4776No
96DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 615040.1080.4761No
97RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 415250.1070.4767No
98PELI1PELI1
Entrez,  Source
pellino homolog 1 (Drosophila)15680.1040.4756No
99NFIBNFIB
Entrez,  Source
nuclear factor I/B15820.1030.4768No
100TGM2TGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)16500.1000.4737No
101GPC3GPC3
Entrez,  Source
glypican 316560.1000.4753No
102PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E16720.0990.4762No
103UPP1UPP1
Entrez,  Source
uridine phosphorylase 116790.0980.4778No
104SLC16A3SLC16A3
Entrez,  Source
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)16900.0980.4790No
105DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)17080.0970.4797No
106AKAP13AKAP13
Entrez,  Source
A kinase (PRKA) anchor protein 1317250.0960.4805No
107COL11A1COL11A1
Entrez,  Source
collagen, type XI, alpha 117490.0950.4806No
108ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta17740.0940.4807No
109FXYD1FXYD1
Entrez,  Source
FXYD domain containing ion transport regulator 1 (phospholemman)17810.0940.4822No
110HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor18490.0910.4789No
111CXCL14CXCL14
Entrez,  Source
chemokine (C-X-C motif) ligand 1418560.0900.4803No
112COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 119420.0870.4756No
113SULF1SULF1
Entrez,  Source
sulfatase 119550.0870.4764No
114LCP2LCP2
Entrez,  Source
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)19580.0870.4781No
115DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 119900.0850.4774No
116ST6GAL1ST6GAL1
Entrez,  Source
ST6 beta-galactosamide alpha-2,6-sialyltranferase 120130.0850.4775No
117PTGER2PTGER2
Entrez,  Source
prostaglandin E receptor 2 (subtype EP2), 53kDa20270.0840.4782No
118GLIPR1GLIPR1
Entrez,  Source
GLI pathogenesis-related 1 (glioma)20280.0840.4799No
119MYRIPMYRIP
Entrez,  Source
myosin VIIA and Rab interacting protein20800.0820.4777No
120APOEAPOE
Entrez,  Source
apolipoprotein E21230.0800.4761No
121CHRDL1CHRDL1
Entrez,  Source
chordin-like 121700.0780.4742No
122TPM4TPM4
Entrez,  Source
tropomyosin 422050.0770.4731No
123SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)22310.0760.4728No
124WISP2WISP2
Entrez,  Source
WNT1 inducible signaling pathway protein 222850.0740.4702No
125NELL2NELL2
Entrez,  Source
NEL-like 2 (chicken)23240.0730.4688No
126CUGBP2CUGBP2
Entrez,  Source
CUG triplet repeat, RNA binding protein 224510.0690.4605No
127TNMDTNMD
Entrez,  Source
tenomodulin24740.0690.4603No
128CSF3CSF3
Entrez,  Source
colony stimulating factor 3 (granulocyte)24830.0690.4610No
129CLIC3CLIC3
Entrez,  Source
chloride intracellular channel 325620.0660.4564No
130SLC19A2SLC19A2
Entrez,  Source
solute carrier family 19 (thiamine transporter), member 226670.0630.4497No
131FN1FN1
Entrez,  Source
fibronectin 127150.0620.4473No
132CTSHCTSH
Entrez,  Source
cathepsin H27230.0620.4481No
133LMO7LMO7
Entrez,  Source
LIM domain 727450.0620.4477No
134TIE1TIE1
Entrez,  Source
tyrosine kinase with immunoglobulin-like and EGF-like domains 127690.0610.4472No
135SELPSELP
Entrez,  Source
selectin P (granule membrane protein 140kDa, antigen CD62)27890.0600.4470No
136TRIB1TRIB1
Entrez,  Source
tribbles homolog 1 (Drosophila)27920.0600.4481No
137ING1ING1
Entrez,  Source
inhibitor of growth family, member 128070.0600.4482No
138BAALCBAALC
Entrez,  Source
brain and acute leukemia, cytoplasmic28190.0600.4486No
139TPST2TPST2
Entrez,  Source
tyrosylprotein sulfotransferase 228560.0590.4471No
140ME1ME1
Entrez,  Source
malic enzyme 1, NADP(+)-dependent, cytosolic29020.0570.4448No
141ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)29350.0570.4435No
142LMO3LMO3
Entrez,  Source
LIM domain only 3 (rhombotin-like 2)30280.0540.4375No
143TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)30340.0540.4382No
144CTSSCTSS
Entrez,  Source
cathepsin S30840.0520.4355No
145JUNJUN
Entrez,  Source
jun oncogene31040.0520.4351No
146MFAP4MFAP4
Entrez,  Source
microfibrillar-associated protein 431050.0520.4362No
147MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)31220.0510.4360No
148AP2S1AP2S1
Entrez,  Source
adaptor-related protein complex 2, sigma 1 subunit31750.0500.4330No
149CYP26B1CYP26B1
Entrez,  Source
cytochrome P450, family 26, subfamily B, polypeptide 132310.0490.4298No
150APODAPOD
Entrez,  Source
apolipoprotein D32550.0480.4290No
151CA4CA4
Entrez,  Source
carbonic anhydrase IV32580.0480.4298No
152JAG2JAG2
Entrez,  Source
jagged 233700.0460.4222No
153DCNDCN
Entrez,  Source
decorin34050.0450.4205No
154FRMD4BFRMD4B
Entrez,  Source
FERM domain containing 4B34220.0450.4202No
155SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 234280.0440.4208No
156GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)34290.0440.4217No
157MCF2LMCF2L
Entrez,  Source
MCF.2 cell line derived transforming sequence-like34540.0440.4207No
158WNT11WNT11
Entrez,  Source
wingless-type MMTV integration site family, member 1134950.0430.4185No
159SEMA3GSEMA3G
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G35580.0420.4146No
160KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)35670.0410.4148No
161MOXD1MOXD1
Entrez,  Source
monooxygenase, DBH-like 136030.0410.4130No
162SEPP1SEPP1
Entrez,  Source
selenoprotein P, plasma, 136250.0400.4122No
163TCF4TCF4
Entrez,  Source
transcription factor 436280.0400.4129No
164PER3PER3
Entrez,  Source
period homolog 3 (Drosophila)36600.0400.4113No
165ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)36810.0390.4106No
166ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa37320.0380.4075No
167SPARCL1SPARCL1
Entrez,  Source
SPARC-like 1 (mast9, hevin)37710.0370.4053No
168F11RF11R
Entrez,  Source
F11 receptor38370.0360.4011No
169JUNDJUND
Entrez,  Source
jun D proto-oncogene38460.0360.4012No
170SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 138800.0350.3994No
171CXCR7CXCR7
Entrez,  Source
chemokine (C-X-C motif) receptor 739530.0340.3945No
172GAS7GAS7
Entrez,  Source
growth arrest-specific 739560.0340.3950No
173NRN1NRN1
Entrez,  Source
neuritin 139570.0340.3957No
174NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)39640.0330.3960No
175KLKL
Entrez,  Source
klotho40120.0330.3930No
176ELOVL5ELOVL5
Entrez,  Source
ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)40370.0320.3918No
177MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 140770.0310.3895No
178DSPDSP
Entrez,  Source
desmoplakin40790.0310.3900No
179RGC32RGC32
Entrez,  Source
-41040.0310.3888No
180NQO1NQO1
Entrez,  Source
NAD(P)H dehydrogenase, quinone 141790.0300.3837No
181SCRG1SCRG1
Entrez,  Source
-42150.0290.3816No
182FLNCFLNC
Entrez,  Source
filamin C, gamma (actin binding protein 280)42300.0290.3811No
183RND1RND1
Entrez,  Source
Rho family GTPase 143180.0270.3750No
184AGTRL1AGTRL1
Entrez,  Source
angiotensin II receptor-like 143380.0270.3741No
185CPECPE
Entrez,  Source
carboxypeptidase E44440.0250.3665No
186RPS6KA2RPS6KA2
Entrez,  Source
ribosomal protein S6 kinase, 90kDa, polypeptide 244600.0240.3658No
187SH2B3SH2B3
Entrez,  Source
SH2B adaptor protein 345230.0230.3615No
188GDF10GDF10
Entrez,  Source
growth differentiation factor 1045640.0220.3589No
189HLFHLF
Entrez,  Source
hepatic leukemia factor46320.0210.3542No
190SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 146970.0200.3496No
191ADRB2ADRB2
Entrez,  Source
adrenergic, beta-2-, receptor, surface47330.0200.3473No
192GGTLA1GGTLA1
Entrez,  Source
gamma-glutamyltransferase-like activity 147610.0190.3457No
193CREMCREM
Entrez,  Source
cAMP responsive element modulator47940.0190.3436No
194SYNPOSYNPO
Entrez,  Source
synaptopodin48980.0170.3360No
195KIAA0101KIAA0101
Entrez,  Source
KIAA010149030.0170.3360No
196ATF5ATF5
Entrez,  Source
activating transcription factor 549370.0160.3338No
197PRKCHPRKCH
Entrez,  Source
protein kinase C, eta49720.0160.3315No
198ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1650420.0140.3265No
199INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)50810.0140.3238No
200FGL2FGL2
Entrez,  Source
fibrinogen-like 250860.0140.3238No
201GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 352320.0110.3129No
202PDE2APDE2A
Entrez,  Source
phosphodiesterase 2A, cGMP-stimulated52640.0110.3107No
203AQP1AQP1
Entrez,  Source
aquaporin 1 (Colton blood group)54000.0090.3005No
204ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 254480.0080.2970No
205CDK7CDK7
Entrez,  Source
cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)55910.0060.2862No
206EPHA3EPHA3
Entrez,  Source
EPH receptor A356210.0050.2840No
207IL15IL15
Entrez,  Source
interleukin 1556740.0050.2801No
208SPATA6SPATA6
Entrez,  Source
spermatogenesis associated 656770.0050.2801No
209WSB2WSB2
Entrez,  Source
WD repeat and SOCS box-containing 256790.0050.2801No
210CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)57040.0040.2783No
211SMAD1SMAD1
Entrez,  Source
SMAD, mothers against DPP homolog 1 (Drosophila)57310.0040.2764No
212LIMK2LIMK2
Entrez,  Source
LIM domain kinase 257430.0040.2756No
213MAOAMAOA
Entrez,  Source
monoamine oxidase A57510.0030.2752No
214ENGENG
Entrez,  Source
endoglin (Osler-Rendu-Weber syndrome 1)57610.0030.2745No
215GIMAP6GIMAP6
Entrez,  Source
GTPase, IMAP family member 658390.0020.2686No
216GLSGLS
Entrez,  Source
glutaminase59350.0010.2613No
217STC2STC2
Entrez,  Source
stanniocalcin 259550.0010.2599No
218SLC1A4SLC1A4
Entrez,  Source
solute carrier family 1 (glutamate/neutral amino acid transporter), member 46096-0.0020.2491No
219CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I6103-0.0020.2487No
220ACSL5ACSL5
Entrez,  Source
acyl-CoA synthetase long-chain family member 56137-0.0020.2462No
221JAM2JAM2
Entrez,  Source
junctional adhesion molecule 26141-0.0020.2460No
222NOX4NOX4
Entrez,  Source
NADPH oxidase 46149-0.0020.2455No
223OXTROXTR
Entrez,  Source
oxytocin receptor6165-0.0020.2444No
224FMO2FMO2
Entrez,  Source
flavin containing monooxygenase 2 (non-functional)6188-0.0030.2428No
225CFICFI
Entrez,  Source
complement factor I6257-0.0040.2376No
226ESR1ESR1
Entrez,  Source
estrogen receptor 16300-0.0050.2345No
227RRADRRAD
Entrez,  Source
Ras-related associated with diabetes6316-0.0050.2334No
228ADAM10ADAM10
Entrez,  Source
ADAM metallopeptidase domain 106375-0.0060.2291No
229ACACBACACB
Entrez,  Source
acetyl-Coenzyme A carboxylase beta6400-0.0060.2274No
230LAPTM5LAPTM5
Entrez,  Source
lysosomal associated multispanning membrane protein 56572-0.0090.2144No
231NINJ2NINJ2
Entrez,  Source
ninjurin 26616-0.0090.2112No
232PLVAPPLVAP
Entrez,  Source
plasmalemma vesicle associated protein6633-0.0100.2102No
233PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M6655-0.0100.2088No
234C3ORF64C3ORF64
Entrez,  Source
chromosome 3 open reading frame 646713-0.0110.2046No
235ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 26736-0.0110.2031No
236EDNRBEDNRB
Entrez,  Source
endothelin receptor type B6802-0.0120.1984No
237CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)6833-0.0130.1963No
238ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 16882-0.0130.1929No
239STC1STC1
Entrez,  Source
stanniocalcin 16986-0.0150.1853No
240HSPB7HSPB7
Entrez,  Source
heat shock 27kDa protein family, member 7 (cardiovascular)7043-0.0160.1813No
241LTBP4LTBP4
Entrez,  Source
latent transforming growth factor beta binding protein 47185-0.0180.1708No
242MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)7189-0.0180.1709No
243CFHCFH
Entrez,  Source
complement factor H7191-0.0180.1712No
244DNM3DNM3
Entrez,  Source
dynamin 37241-0.0190.1678No
245CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 27253-0.0190.1674No
246CDH2CDH2
Entrez,  Source
cadherin 2, type 1, N-cadherin (neuronal)7290-0.0190.1650No
247HAPLN1HAPLN1
Entrez,  Source
hyaluronan and proteoglycan link protein 17300-0.0200.1647No
248GATA2GATA2
Entrez,  Source
GATA binding protein 27313-0.0200.1642No
249DNM1DNM1
Entrez,  Source
dynamin 17344-0.0200.1623No
250COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 17379-0.0210.1601No
251PPARGPPARG
Entrez,  Source
peroxisome proliferative activated receptor, gamma7396-0.0210.1593No
252ALDH1A2ALDH1A2
Entrez,  Source
aldehyde dehydrogenase 1 family, member A27402-0.0210.1593No
253EMCNEMCN
Entrez,  Source
endomucin7455-0.0220.1558No
254ANGPT2ANGPT2
Entrez,  Source
angiopoietin 27458-0.0220.1561No
255MTUS1MTUS1
Entrez,  Source
mitochondrial tumor suppressor 17482-0.0220.1548No
256ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein7557-0.0230.1495No
257PDGFRLPDGFRL
Entrez,  Source
platelet-derived growth factor receptor-like7568-0.0240.1493No
258DMNDMN
Entrez,  Source
desmuslin7569-0.0240.1497No
259PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)7649-0.0250.1442No
260NOVA1NOVA1
Entrez,  Source
neuro-oncological ventral antigen 17658-0.0250.1441No
261ACLYACLY
Entrez,  Source
ATP citrate lyase7774-0.0270.1358No
262SOCS3SOCS3
Entrez,  Source
suppressor of cytokine signaling 37799-0.0270.1345No
263C6C6
Entrez,  Source
complement component 67841-0.0280.1319No
264F10F10
Entrez,  Source
coagulation factor X7895-0.0290.1284No
265NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 97899-0.0290.1288No
266MCFD2MCFD2
Entrez,  Source
multiple coagulation factor deficiency 27936-0.0300.1266No
267PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 37937-0.0300.1272No
268IGF1IGF1
Entrez,  Source
insulin-like growth factor 1 (somatomedin C)7950-0.0300.1269No
269CYP1B1CYP1B1
Entrez,  Source
cytochrome P450, family 1, subfamily B, polypeptide 17989-0.0310.1246No
270NPY1RNPY1R
Entrez,  Source
neuropeptide Y receptor Y18092-0.0320.1174No
271CTSKCTSK
Entrez,  Source
cathepsin K (pycnodysostosis)8117-0.0320.1162No
272COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein8125-0.0330.1164No
273KCNK2KCNK2
Entrez,  Source
potassium channel, subfamily K, member 28139-0.0330.1161No
274PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)8146-0.0330.1163No
275PIK3R3PIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)8161-0.0330.1159No
276VWFVWF
Entrez,  Source
von Willebrand factor8376-0.0370.1001No
277CDC37CDC37
Entrez,  Source
CDC37 cell division cycle 37 homolog (S. cerevisiae)8391-0.0370.0998No
278ELTD1ELTD1
Entrez,  Source
EGF, latrophilin and seven transmembrane domain containing 18400-0.0370.1000No
279KCNAB1KCNAB1
Entrez,  Source
potassium voltage-gated channel, shaker-related subfamily, beta member 18440-0.0380.0978No
280FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)8465-0.0380.0967No
281CAPN6CAPN6
Entrez,  Source
calpain 68491-0.0390.0956No
282SCG5SCG5
Entrez,  Source
secretogranin V (7B2 protein)8494-0.0390.0962No
283IER5IER5
Entrez,  Source
immediate early response 58527-0.0390.0946No
284ASNSASNS
Entrez,  Source
asparagine synthetase8596-0.0400.0902No
285TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein8667-0.0410.0856No
286NR5A2NR5A2
Entrez,  Source
nuclear receptor subfamily 5, group A, member 28704-0.0420.0837No
287CD14CD14
Entrez,  Source
CD14 molecule8706-0.0420.0845No
288LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)8708-0.0420.0853No
289SLCO4A1SLCO4A1
Entrez,  Source
solute carrier organic anion transporter family, member 4A18782-0.0430.0806No
290SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 38829-0.0440.0779No
291TRPC4TRPC4
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 49085-0.0490.0593No
292GIMAP4GIMAP4
Entrez,  Source
GTPase, IMAP family member 49106-0.0490.0587No
293FHL2FHL2
Entrez,  Source
four and a half LIM domains 29173-0.0500.0547No
294TMPOTMPO
Entrez,  Source
thymopoietin9189-0.0500.0546No
295GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb9192-0.0500.0555No
296HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed9234-0.0510.0534No
297CD93CD93
Entrez,  Source
CD93 molecule9341-0.0530.0463No
298SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)9458-0.0550.0385No
299NR1H3NR1H3
Entrez,  Source
nuclear receptor subfamily 1, group H, member 39459-0.0550.0396No
300CLDN5CLDN5
Entrez,  Source
claudin 5 (transmembrane protein deleted in velocardiofacial syndrome)9647-0.0590.0264No
301EIF5EIF5
Entrez,  Source
eukaryotic translation initiation factor 59653-0.0590.0272No
302FRZBFRZB
Entrez,  Source
frizzled-related protein9829-0.0630.0150No
303PGK1PGK1
Entrez,  Source
phosphoglycerate kinase 19880-0.0640.0125No
304PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule10004-0.0660.0044No
305KCNS3KCNS3
Entrez,  Source
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 310019-0.0670.0047No
306MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response10189-0.070-0.0069No
307COLEC12COLEC12
Entrez,  Source
collectin sub-family member 1210217-0.071-0.0075No
308SRPXSRPX
Entrez,  Source
sushi-repeat-containing protein, X-linked10360-0.074-0.0169No
309AOC3AOC3
Entrez,  Source
amine oxidase, copper containing 3 (vascular adhesion protein 1)10438-0.076-0.0213No
310TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)10443-0.076-0.0200No
311SELESELE
Entrez,  Source
selectin E (endothelial adhesion molecule 1)10446-0.076-0.0186No
312MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)10547-0.079-0.0247No
313BAXBAX
Entrez,  Source
BCL2-associated X protein10615-0.080-0.0282No
314EIF2S2EIF2S2
Entrez,  Source
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa10731-0.084-0.0354No
315BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 210960-0.089-0.0511No
316UCHL1UCHL1
Entrez,  Source
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)11042-0.092-0.0555No
317TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa11066-0.092-0.0553No
318TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 211118-0.094-0.0573No
319GMFGGMFG
Entrez,  Source
glia maturation factor, gamma11174-0.095-0.0596No
320SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 111210-0.096-0.0603No
321WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A11232-0.097-0.0600No
322SFRS7SFRS7
Entrez,  Source
splicing factor, arginine/serine-rich 7, 35kDa11272-0.098-0.0609No
323NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 211369-0.101-0.0663No
324WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase11445-0.104-0.0699No
325RAI14RAI14
Entrez,  Source
retinoic acid induced 1411447-0.104-0.0678No
326GFPT1GFPT1
Entrez,  Source
glutamine-fructose-6-phosphate transaminase 111452-0.104-0.0660No
327IRF1IRF1
Entrez,  Source
interferon regulatory factor 111466-0.105-0.0648No
328SHMT2SHMT2
Entrez,  Source
serine hydroxymethyltransferase 2 (mitochondrial)11474-0.105-0.0632No
329ITGA6ITGA6
Entrez,  Source
integrin, alpha 611513-0.106-0.0639No
330PRKD1PRKD1
Entrez,  Source
protein kinase D111594-0.109-0.0679No
331TRIB3TRIB3
Entrez,  Source
tribbles homolog 3 (Drosophila)11605-0.110-0.0664No
332YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase11607-0.110-0.0642No
333EIF1EIF1
Entrez,  Source
eukaryotic translation initiation factor 111662-0.112-0.0660No
334SOD2SOD2
Entrez,  Source
superoxide dismutase 2, mitochondrial11710-0.114-0.0673No
335TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)11720-0.114-0.0657No
336PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 511910-0.122-0.0777No
337GPR56GPR56
Entrez,  Source
G protein-coupled receptor 5612030-0.128-0.0843No
338A2MA2M
Entrez,  Source
alpha-2-macroglobulin12069-0.130-0.0845No
339NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)12092-0.131-0.0835No
340EFNA1EFNA1
Entrez,  Source
ephrin-A112095-0.131-0.0810No
341NDRG2NDRG2
Entrez,  Source
NDRG family member 212174-0.135-0.0842No
342TSPAN6TSPAN6
Entrez,  Source
tetraspanin 612255-0.140-0.0875No
343PODXLPODXL
Entrez,  Source
podocalyxin-like12264-0.140-0.0852No
344PSAT1PSAT1
Entrez,  Source
phosphoserine aminotransferase 112281-0.141-0.0835No
345BCHEBCHE
Entrez,  Source
butyrylcholinesterase12286-0.141-0.0809No
346ARTS-1ARTS-1
Entrez,  Source
-12308-0.143-0.0796No
347IFI44IFI44
Entrez,  Source
interferon-induced protein 4412405-0.149-0.0839No
348USP3USP3
Entrez,  Source
ubiquitin specific peptidase 312588-0.162-0.0946No
349GIMAP5GIMAP5
Entrez,  Source
GTPase, IMAP family member 512589-0.162-0.0912No
350SLC7A1SLC7A1
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 112592-0.163-0.0880No
351METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)12611-0.164-0.0860No
352TXNRD1TXNRD1
Entrez,  Source
thioredoxin reductase 112775-0.181-0.0949No
353DOCK9DOCK9
Entrez,  Source
dedicator of cytokinesis 912801-0.185-0.0930No
354CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)12802-0.185-0.0891No
355CYP4B1CYP4B1
Entrez,  Source
cytochrome P450, family 4, subfamily B, polypeptide 112818-0.188-0.0864No
356EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)12857-0.193-0.0854No
357MX2MX2
Entrez,  Source
myxovirus (influenza virus) resistance 2 (mouse)12876-0.196-0.0827No
358GBP2GBP2
Entrez,  Source
guanylate binding protein 2, interferon-inducible12940-0.207-0.0833No
359GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 1113005-0.219-0.0837No
360ZBTB10ZBTB10
Entrez,  Source
zinc finger and BTB domain containing 1013012-0.220-0.0796No
361HNRPMHNRPM
Entrez,  Source
heterogeneous nuclear ribonucleoprotein M13088-0.247-0.0803No
362FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 113123-0.259-0.0776No
363G0S2G0S2
Entrez,  Source
G0/G1switch 213137-0.265-0.0732No
364SLC7A5SLC7A5
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 513201-0.300-0.0718No
365BST2BST2
Entrez,  Source
bone marrow stromal cell antigen 213220-0.317-0.0667No
366CES1CES1
Entrez,  Source
carboxylesterase 1 (monocyte/macrophage serine esterase 1)13281-0.399-0.0631No
367ABCC4ABCC4
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 413299-0.446-0.0552No
368CXCL10CXCL10
Entrez,  Source
chemokine (C-X-C motif) ligand 1013301-0.450-0.0460No
369GADD45GGADD45G
Entrez,  Source
growth arrest and DNA-damage-inducible, gamma13302-0.454-0.0366No
370PPP1R3CPPP1R3C
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3C13309-0.475-0.0273No
371CD74CD74
Entrez,  Source
CD74 molecule, major histocompatibility complex, class II invariant chain13325-0.617-0.0157No
372EDG1EDG1
Entrez,  Source
endothelial differentiation, sphingolipid G-protein-coupled receptor, 113334-0.8220.0006No
Table: GSEA details [plain text format]



Fig 2: BOQUEST_CD31PLUS_VS_CD31MINUS_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BOQUEST_CD31PLUS_VS_CD31MINUS_UP: Random ES distribution   
Gene set null distribution of ES for BOQUEST_CD31PLUS_VS_CD31MINUS_UP