Details for gene set CALCIUM_REGULATION_IN_CARDIAC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	CALCIUM_REGULATION_IN_CARDIAC_CELLS
Enrichment Score (ES)	0.4881081
Normalized Enrichment Score (NES)	1.8058915
Nominal p-value	0.0
FDR q-value	0.0245353
FWER p-Value	0.96

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	25	0.771	0.0688	Yes
2	RGS1	RGS1 Entrez, Source	regulator of G-protein signalling 1	75	0.565	0.1169	Yes
3	RGS16	RGS16 Entrez, Source	regulator of G-protein signalling 16	103	0.505	0.1612	Yes
4	GRK5	GRK5 Entrez, Source	G protein-coupled receptor kinase 5	115	0.484	0.2047	Yes
5	PRKAR2B	PRKAR2B Entrez, Source	protein kinase, cAMP-dependent, regulatory, type II, beta	160	0.434	0.2412	Yes
6	GJA1	GJA1 Entrez, Source	gap junction protein, alpha 1, 43kDa (connexin 43)	173	0.414	0.2782	Yes
7	PEA15	PEA15 Entrez, Source	phosphoprotein enriched in astrocytes 15	279	0.322	0.2998	Yes
8	RGS3	RGS3 Entrez, Source	regulator of G-protein signalling 3	338	0.287	0.3217	Yes
9	PRKAR1B	PRKAR1B Entrez, Source	protein kinase, cAMP-dependent, regulatory, type I, beta	369	0.272	0.3444	Yes
10	RGS10	RGS10 Entrez, Source	regulator of G-protein signalling 10	370	0.272	0.3694	Yes
11	PKIB	PKIB Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor beta	446	0.246	0.3863	Yes
12	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	454	0.244	0.4081	Yes
13	GJB3	GJB3 Entrez, Source	gap junction protein, beta 3, 31kDa (connexin 31)	475	0.236	0.4282	Yes
14	RGS5	RGS5 Entrez, Source	regulator of G-protein signalling 5	513	0.224	0.4459	Yes
15	GJB5	GJB5 Entrez, Source	gap junction protein, beta 5 (connexin 31.1)	534	0.219	0.4645	Yes
16	ITPR1	ITPR1 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 1	816	0.167	0.4586	Yes
17	GNAI2	GNAI2 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	931	0.153	0.4640	Yes
18	YWHAQ	YWHAQ Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	1294	0.120	0.4477	Yes
19	PKIA	PKIA Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	1340	0.117	0.4550	Yes
20	ATP2A3	ATP2A3 Entrez, Source	ATPase, Ca++ transporting, ubiquitous	1390	0.114	0.4618	Yes
21	PLN	PLN Entrez, Source	phospholamban	1420	0.112	0.4699	Yes
22	ANXA6	ANXA6 Entrez, Source	annexin A6	1439	0.111	0.4787	Yes
23	PRKCA	PRKCA Entrez, Source	protein kinase C, alpha	1663	0.099	0.4710	Yes
24	CACNA1E	CACNA1E Entrez, Source	calcium channel, voltage-dependent, alpha 1E subunit	1771	0.094	0.4715	Yes
25	GJB1	GJB1 Entrez, Source	gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)	1871	0.090	0.4722	Yes
26	GNB5	GNB5 Entrez, Source	guanine nucleotide binding protein (G protein), beta 5	1878	0.089	0.4800	Yes
27	PKIG	PKIG Entrez, Source	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	1880	0.089	0.4881	Yes
28	ATP1B1	ATP1B1 Entrez, Source	ATPase, Na+/K+ transporting, beta 1 polypeptide	2395	0.071	0.4557	No
29	ADCY6	ADCY6 Entrez, Source	adenylate cyclase 6	2414	0.070	0.4608	No
30	PRKAR1A	PRKAR1A Entrez, Source	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	2585	0.065	0.4540	No
31	CAMK1	CAMK1 Entrez, Source	calcium/calmodulin-dependent protein kinase I	2617	0.064	0.4575	No
32	ATP1A4	ATP1A4 Entrez, Source	ATPase, Na+/K+ transporting, alpha 4 polypeptide	2855	0.059	0.4450	No
33	GNAQ	GNAQ Entrez, Source	guanine nucleotide binding protein (G protein), q polypeptide	2897	0.057	0.4471	No
34	ITPR3	ITPR3 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 3	2923	0.057	0.4505	No
35	ARRB1	ARRB1 Entrez, Source	arrestin, beta 1	3016	0.054	0.4484	No
36	GNAI3	GNAI3 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	3147	0.051	0.4433	No
37	PLCB3	PLCB3 Entrez, Source	phospholipase C, beta 3 (phosphatidylinositol-specific)	3154	0.051	0.4475	No
38	CALM3	CALM3 Entrez, Source	calmodulin 3 (phosphorylase kinase, delta)	3289	0.048	0.4417	No
39	NME7	NME7 Entrez, Source	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)	3369	0.046	0.4399	No
40	ADRA1D	ADRA1D Entrez, Source	adrenergic, alpha-1D-, receptor	3501	0.043	0.4339	No
41	GNB4	GNB4 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 4	3549	0.042	0.4342	No
42	CHRM2	CHRM2 Entrez, Source	cholinergic receptor, muscarinic 2	3622	0.040	0.4325	No
43	CAMK2A	CAMK2A Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha	3720	0.038	0.4286	No
44	CACNA1D	CACNA1D Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1D subunit	3745	0.038	0.4303	No
45	CACNB3	CACNB3 Entrez, Source	calcium channel, voltage-dependent, beta 3 subunit	3774	0.037	0.4316	No
46	PRKCD	PRKCD Entrez, Source	protein kinase C, delta	3824	0.036	0.4311	No
47	RYR2	RYR2 Entrez, Source	ryanodine receptor 2 (cardiac)	4005	0.033	0.4205	No
48	KCNB1	KCNB1 Entrez, Source	potassium voltage-gated channel, Shab-related subfamily, member 1	4161	0.030	0.4116	No
49	GNG5	GNG5 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 5	4174	0.030	0.4134	No
50	GNB2	GNB2 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 2	4175	0.030	0.4161	No
51	KCNJ3	KCNJ3 Entrez, Source	potassium inwardly-rectifying channel, subfamily J, member 3	4308	0.027	0.4086	No
52	YWHAB	YWHAB Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	4394	0.025	0.4045	No
53	PRKCZ	PRKCZ Entrez, Source	protein kinase C, zeta	4529	0.023	0.3965	No
54	RGS7	RGS7 Entrez, Source	regulator of G-protein signalling 7	4582	0.022	0.3945	No
55	ADRB3	ADRB3 Entrez, Source	adrenergic, beta-3-, receptor	4672	0.021	0.3897	No
56	ADRB2	ADRB2 Entrez, Source	adrenergic, beta-2-, receptor, surface	4733	0.020	0.3869	No
57	ATP2B3	ATP2B3 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 3	4775	0.019	0.3855	No
58	ADCY5	ADCY5 Entrez, Source	adenylate cyclase 5	4781	0.019	0.3869	No
59	PRKCH	PRKCH Entrez, Source	protein kinase C, eta	4972	0.016	0.3739	No
60	GNG7	GNG7 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 7	5497	0.007	0.3350	No
61	CAMK4	CAMK4 Entrez, Source	calcium/calmodulin-dependent protein kinase IV	5529	0.007	0.3333	No
62	GJB2	GJB2 Entrez, Source	gap junction protein, beta 2, 26kDa (connexin 26)	5644	0.005	0.3251	No
63	ARRB2	ARRB2 Entrez, Source	arrestin, beta 2	5791	0.003	0.3143	No
64	GNAZ	GNAZ Entrez, Source	guanine nucleotide binding protein (G protein), alpha z polypeptide	5810	0.003	0.3132	No
65	CAMK2G	CAMK2G Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma	5913	0.001	0.3056	No
66	FXYD2	FXYD2 Entrez, Source	FXYD domain containing ion transport regulator 2	5938	0.001	0.3039	No
67	GNB3	GNB3 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 3	6067	-0.001	0.2943	No
68	CHRM4	CHRM4 Entrez, Source	cholinergic receptor, muscarinic 4	6218	-0.003	0.2833	No
69	PRKACA	PRKACA Entrez, Source	protein kinase, cAMP-dependent, catalytic, alpha	6428	-0.007	0.2681	No
70	RYR1	RYR1 Entrez, Source	ryanodine receptor 1 (skeletal)	6453	-0.007	0.2669	No
71	YWHAH	YWHAH Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	6649	-0.010	0.2531	No
72	ITPR2	ITPR2 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 2	6675	-0.010	0.2521	No
73	CHRM5	CHRM5 Entrez, Source	cholinergic receptor, muscarinic 5	6708	-0.011	0.2507	No
74	KCNJ5	KCNJ5 Entrez, Source	potassium inwardly-rectifying channel, subfamily J, member 5	6781	-0.012	0.2463	No
75	RGS6	RGS6 Entrez, Source	regulator of G-protein signalling 6	6832	-0.013	0.2437	No
76	GJA4	GJA4 Entrez, Source	gap junction protein, alpha 4, 37kDa (connexin 37)	6909	-0.014	0.2392	No
77	GRK4	GRK4 Entrez, Source	G protein-coupled receptor kinase 4	6984	-0.015	0.2350	No
78	CALM2	CALM2 Entrez, Source	calmodulin 2 (phosphorylase kinase, delta)	7147	-0.017	0.2243	No
79	CACNA1B	CACNA1B Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1B subunit	7282	-0.019	0.2160	No
80	ADRB1	ADRB1 Entrez, Source	adrenergic, beta-1-, receptor	7285	-0.019	0.2176	No
81	CACNA1C	CACNA1C Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1C subunit	7330	-0.020	0.2161	No
82	SLC8A1	SLC8A1 Entrez, Source	solute carrier family 8 (sodium/calcium exchanger), member 1	7449	-0.022	0.2092	No
83	RGS9	RGS9 Entrez, Source	regulator of G-protein signalling 9	7456	-0.022	0.2107	No
84	GNG3	GNG3 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 3	7522	-0.023	0.2079	No
85	ADCY2	ADCY2 Entrez, Source	adenylate cyclase 2 (brain)	7570	-0.024	0.2065	No
86	ADRA1A	ADRA1A Entrez, Source	adrenergic, alpha-1A-, receptor	7726	-0.026	0.1972	No
87	PRKAR2A	PRKAR2A Entrez, Source	protein kinase, cAMP-dependent, regulatory, type II, alpha	7798	-0.027	0.1943	No
88	GNAO1	GNAO1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	7919	-0.029	0.1880	No
89	CAMK2D	CAMK2D Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta	7932	-0.030	0.1898	No
90	GJB4	GJB4 Entrez, Source	gap junction protein, beta 4 (connexin 30.3)	7942	-0.030	0.1918	No
91	ATP2A2	ATP2A2 Entrez, Source	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	7943	-0.030	0.1946	No
92	GRK6	GRK6 Entrez, Source	G protein-coupled receptor kinase 6	8007	-0.031	0.1926	No
93	PRKCE	PRKCE Entrez, Source	protein kinase C, epsilon	8210	-0.034	0.1805	No
94	CAMK2B	CAMK2B Entrez, Source	calcium/calmodulin-dependent protein kinase (CaM kinase) II beta	8673	-0.041	0.1493	No
95	ADCY8	ADCY8 Entrez, Source	adenylate cyclase 8 (brain)	8892	-0.045	0.1370	No
96	CALR	CALR Entrez, Source	calreticulin	9052	-0.048	0.1294	No
97	ATP1B2	ATP1B2 Entrez, Source	ATPase, Na+/K+ transporting, beta 2 polypeptide	9203	-0.051	0.1227	No
98	CACNA1A	CACNA1A Entrez, Source	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	9227	-0.051	0.1256	No
99	ATP1B3	ATP1B3 Entrez, Source	ATPase, Na+/K+ transporting, beta 3 polypeptide	9230	-0.051	0.1302	No
100	SLC8A3	SLC8A3 Entrez, Source	solute carrier family 8 (sodium-calcium exchanger), member 3	9258	-0.052	0.1329	No
101	PRKCQ	PRKCQ Entrez, Source	protein kinase C, theta	9522	-0.056	0.1182	No
102	GNG12	GNG12 Entrez, Source	guanine nucleotide binding protein (G protein), gamma 12	9681	-0.059	0.1117	No
103	CACNB1	CACNB1 Entrez, Source	calcium channel, voltage-dependent, beta 1 subunit	9858	-0.063	0.1041	No
104	CACNA1S	CACNA1S Entrez, Source	calcium channel, voltage-dependent, L type, alpha 1S subunit	9910	-0.065	0.1062	No
105	CHRM3	CHRM3 Entrez, Source	cholinergic receptor, muscarinic 3	10072	-0.068	0.1003	No
106	CALM1	CALM1 Entrez, Source	calmodulin 1 (phosphorylase kinase, delta)	10213	-0.071	0.0962	No
107	ATP2B1	ATP2B1 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 1	10314	-0.073	0.0953	No
108	GJB6	GJB6 Entrez, Source	gap junction protein, beta 6 (connexin 30)	10353	-0.074	0.0992	No
109	ADCY3	ADCY3 Entrez, Source	adenylate cyclase 3	10657	-0.081	0.0837	No
110	ATP2B2	ATP2B2 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 2	10683	-0.082	0.0893	No
111	GJA5	GJA5 Entrez, Source	gap junction protein, alpha 5, 40kDa (connexin 40)	10784	-0.085	0.0895	No
112	RGS19	RGS19 Entrez, Source	regulator of G-protein signalling 19	10872	-0.087	0.0910	No
113	GNA11	GNA11 Entrez, Source	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	10947	-0.089	0.0935	No
114	CASQ2	CASQ2 Entrez, Source	calsequestrin 2 (cardiac muscle)	11010	-0.091	0.0972	No
115	PRKCB1	PRKCB1 Entrez, Source	protein kinase C, beta 1	11192	-0.096	0.0922	No
116	RGS14	RGS14 Entrez, Source	regulator of G-protein signalling 14	11575	-0.108	0.0733	No
117	PRKD1	PRKD1 Entrez, Source	protein kinase D1	11594	-0.109	0.0819	No
118	GNB1	GNB1 Entrez, Source	guanine nucleotide binding protein (G protein), beta polypeptide 1	11712	-0.114	0.0835	No
119	ADRA1B	ADRA1B Entrez, Source	adrenergic, alpha-1B-, receptor	11763	-0.115	0.0903	No
120	CHRM1	CHRM1 Entrez, Source	cholinergic receptor, muscarinic 1	12509	-0.155	0.0482	No
121	ADCY4	ADCY4 Entrez, Source	adenylate cyclase 4	12581	-0.161	0.0576	No