Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | CANCER_NEOPLASTIC_META_UP |
| Enrichment Score (ES) | -0.3845178 |
| Normalized Enrichment Score (NES) | -1.2475499 |
| Nominal p-value | 0.14725275 |
| FDR q-value | 0.5237495 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 6 | 1.154 | 0.2535 | No |
| 2 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 1094 | 0.137 | 0.2020 | No |
| 3 | AHCY | AHCY Entrez, Source | S-adenosylhomocysteine hydrolase | 1169 | 0.131 | 0.2252 | No |
| 4 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 4069 | 0.032 | 0.0143 | No |
| 5 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 4192 | 0.029 | 0.0116 | No |
| 6 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 4541 | 0.022 | -0.0096 | No |
| 7 | COPB2 | COPB2 Entrez, Source | coatomer protein complex, subunit beta 2 (beta prime) | 4784 | 0.019 | -0.0237 | No |
| 8 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.0289 | No |
| 9 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 5536 | 0.007 | -0.0749 | No |
| 10 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 6475 | -0.007 | -0.1438 | No |
| 11 | CBX3 | CBX3 Entrez, Source | chromobox homolog 3 (HP1 gamma homolog, Drosophila) | 6693 | -0.011 | -0.1578 | No |
| 12 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 7283 | -0.019 | -0.1978 | No |
| 13 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 7774 | -0.027 | -0.2286 | No |
| 14 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 7811 | -0.028 | -0.2253 | No |
| 15 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 8646 | -0.041 | -0.2789 | No |
| 16 | G3BP | G3BP Entrez, Source | - | 8799 | -0.044 | -0.2807 | No |
| 17 | CANX | CANX Entrez, Source | calnexin | 8835 | -0.044 | -0.2736 | No |
| 18 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9384 | -0.054 | -0.3029 | No |
| 19 | HSPE1 | HSPE1 Entrez, Source | heat shock 10kDa protein 1 (chaperonin 10) | 9837 | -0.063 | -0.3230 | No |
| 20 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10056 | -0.067 | -0.3245 | No |
| 21 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 10249 | -0.072 | -0.3232 | No |
| 22 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11066 | -0.092 | -0.3642 | Yes |
| 23 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 11212 | -0.096 | -0.3540 | Yes |
| 24 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 11472 | -0.105 | -0.3504 | Yes |
| 25 | CCT4 | CCT4 Entrez, Source | chaperonin containing TCP1, subunit 4 (delta) | 11590 | -0.109 | -0.3352 | Yes |
| 26 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 11730 | -0.114 | -0.3205 | Yes |
| 27 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 11749 | -0.115 | -0.2966 | Yes |
| 28 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 11852 | -0.119 | -0.2780 | Yes |
| 29 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12150 | -0.134 | -0.2708 | Yes |
| 30 | PSME2 | PSME2 Entrez, Source | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 12296 | -0.142 | -0.2504 | Yes |
| 31 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 12324 | -0.144 | -0.2207 | Yes |
| 32 | SSR1 | SSR1 Entrez, Source | signal sequence receptor, alpha (translocon-associated protein alpha) | 12408 | -0.149 | -0.1942 | Yes |
| 33 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 12489 | -0.154 | -0.1663 | Yes |
| 34 | PAFAH1B3 | PAFAH1B3 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa | 12578 | -0.161 | -0.1376 | Yes |
| 35 | TUBB | TUBB Entrez, Source | tubulin, beta | 12909 | -0.201 | -0.1182 | Yes |
| 36 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 12993 | -0.216 | -0.0768 | Yes |
| 37 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13307 | -0.468 | 0.0026 | Yes |
