Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | CANTHARIDIN_DN |
| Enrichment Score (ES) | -0.59763074 |
| Normalized Enrichment Score (NES) | -1.804167 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.04688884 |
| FWER p-Value | 0.895 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1594 | 0.103 | -0.0871 | No |
| 2 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 1624 | 0.101 | -0.0572 | No |
| 3 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 1728 | 0.096 | -0.0344 | No |
| 4 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 2381 | 0.071 | -0.0608 | No |
| 5 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 3950 | 0.034 | -0.1679 | No |
| 6 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 4048 | 0.032 | -0.1650 | No |
| 7 | ATP5G3 | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 5923 | 0.001 | -0.3054 | No |
| 8 | ABCA3 | ABCA3 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 3 | 6472 | -0.007 | -0.3443 | No |
| 9 | TRAP1 | TRAP1 Entrez, Source | TNF receptor-associated protein 1 | 6975 | -0.015 | -0.3773 | No |
| 10 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 7875 | -0.029 | -0.4358 | No |
| 11 | RPL29 | RPL29 Entrez, Source | ribosomal protein L29 | 9941 | -0.065 | -0.5703 | No |
| 12 | SLK | SLK Entrez, Source | STE20-like kinase (yeast) | 10306 | -0.073 | -0.5746 | Yes |
| 13 | RPL4 | RPL4 Entrez, Source | ribosomal protein L4 | 10426 | -0.075 | -0.5597 | Yes |
| 14 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.5437 | Yes |
| 15 | FARSLB | FARSLB Entrez, Source | phenylalanine-tRNA synthetase-like, beta subunit | 10582 | -0.079 | -0.5210 | Yes |
| 16 | RPL15 | RPL15 Entrez, Source | ribosomal protein L15 | 11041 | -0.091 | -0.5265 | Yes |
| 17 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11221 | -0.096 | -0.5094 | Yes |
| 18 | EIF3S9 | EIF3S9 Entrez, Source | eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa | 11339 | -0.100 | -0.4865 | Yes |
| 19 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 11381 | -0.101 | -0.4575 | Yes |
| 20 | GTF3A | GTF3A Entrez, Source | general transcription factor IIIA | 11457 | -0.104 | -0.4300 | Yes |
| 21 | EEF1D | EEF1D Entrez, Source | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 11614 | -0.110 | -0.4070 | Yes |
| 22 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 11673 | -0.112 | -0.3758 | Yes |
| 23 | HNRPC | HNRPC Entrez, Source | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 11740 | -0.115 | -0.3444 | Yes |
| 24 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 12121 | -0.133 | -0.3310 | Yes |
| 25 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 12204 | -0.137 | -0.2937 | Yes |
| 26 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12284 | -0.141 | -0.2549 | Yes |
| 27 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 12316 | -0.144 | -0.2117 | Yes |
| 28 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1939 | Yes |
| 29 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 13076 | -0.242 | -0.1214 | Yes |
| 30 | ABCC4 | ABCC4 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 13299 | -0.446 | 0.0032 | Yes |
