Details for gene set CATABOLIC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	CATABOLIC_PROCESS
Enrichment Score (ES)	0.49903825
Normalized Enrichment Score (NES)	1.8961799
Nominal p-value	0.0
FDR q-value	0.013057268
FWER p-Value	0.626

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CPT1A	CPT1A Entrez, Source	carnitine palmitoyltransferase 1A (liver)	47	0.660	0.0434	Yes
2	HAO2	HAO2 Entrez, Source	hydroxyacid oxidase 2 (long chain)	54	0.630	0.0877	Yes
3	PFKFB1	PFKFB1 Entrez, Source	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	133	0.466	0.1150	Yes
4	GOT1	GOT1 Entrez, Source	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	144	0.453	0.1464	Yes
5	HGD	HGD Entrez, Source	homogentisate 1,2-dioxygenase (homogentisate oxidase)	146	0.449	0.1782	Yes
6	AMPD3	AMPD3 Entrez, Source	adenosine monophosphate deaminase (isoform E)	167	0.426	0.2070	Yes
7	MIOX	MIOX Entrez, Source	myo-inositol oxygenase	178	0.406	0.2351	Yes
8	ECH1	ECH1 Entrez, Source	enoyl Coenzyme A hydratase 1, peroxisomal	181	0.405	0.2638	Yes
9	GPX3	GPX3 Entrez, Source	glutathione peroxidase 3 (plasma)	199	0.391	0.2903	Yes
10	CES2	CES2 Entrez, Source	carboxylesterase 2 (intestine, liver)	227	0.365	0.3142	Yes
11	HK1	HK1 Entrez, Source	hexokinase 1	251	0.342	0.3368	Yes
12	APOA4	APOA4 Entrez, Source	apolipoprotein A-IV	253	0.340	0.3609	Yes
13	BCKDHA	BCKDHA Entrez, Source	branched chain keto acid dehydrogenase E1, alpha polypeptide	272	0.326	0.3827	Yes
14	STS	STS Entrez, Source	steroid sulfatase (microsomal), arylsulfatase C, isozyme S	288	0.316	0.4040	Yes
15	DDAH1	DDAH1 Entrez, Source	dimethylarginine dimethylaminohydrolase 1	421	0.254	0.4121	Yes
16	DDAH2	DDAH2 Entrez, Source	dimethylarginine dimethylaminohydrolase 2	501	0.227	0.4223	Yes
17	ECHS1	ECHS1 Entrez, Source	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	585	0.209	0.4308	Yes
18	ARG1	ARG1 Entrez, Source	arginase, liver	704	0.185	0.4350	Yes
19	PPT1	PPT1 Entrez, Source	palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)	810	0.168	0.4390	Yes
20	HACL1	HACL1 Entrez, Source	2-hydroxyacyl-CoA lyase 1	839	0.164	0.4486	Yes
21	COLQ	COLQ Entrez, Source	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	888	0.157	0.4562	Yes
22	ACADS	ACADS Entrez, Source	acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain	1025	0.145	0.4561	Yes
23	GUSB	GUSB Entrez, Source	glucuronidase, beta	1047	0.142	0.4646	Yes
24	LYPLA3	LYPLA3 Entrez, Source	lysophospholipase 3 (lysosomal phospholipase A2)	1075	0.138	0.4724	Yes
25	APOA5	APOA5 Entrez, Source	apolipoprotein A-V	1126	0.134	0.4782	Yes
26	RNASE6	RNASE6 Entrez, Source	ribonuclease, RNase A family, k6	1246	0.124	0.4780	Yes
27	BCKDHB	BCKDHB Entrez, Source	branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)	1252	0.124	0.4864	Yes
28	ZFP36	ZFP36 Entrez, Source	zinc finger protein 36, C3H type, homolog (mouse)	1260	0.123	0.4946	Yes
29	FAH	FAH Entrez, Source	fumarylacetoacetate hydrolase (fumarylacetoacetase)	1315	0.119	0.4990	Yes
30	SMPD3	SMPD3 Entrez, Source	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	1478	0.109	0.4945	Yes
31	ALDOA	ALDOA Entrez, Source	aldolase A, fructose-bisphosphate	1564	0.104	0.4955	Yes
32	PFKL	PFKL Entrez, Source	phosphofructokinase, liver	1624	0.101	0.4982	Yes
33	ACO2	ACO2 Entrez, Source	aconitase 2, mitochondrial	1737	0.096	0.4965	Yes
34	GNS	GNS Entrez, Source	glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID)	1850	0.091	0.4945	Yes
35	GAA	GAA Entrez, Source	glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)	1940	0.087	0.4940	Yes
36	GLUD1	GLUD1 Entrez, Source	glutamate dehydrogenase 1	1962	0.087	0.4985	Yes
37	UBE2B	UBE2B Entrez, Source	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	2086	0.081	0.4950	Yes
38	MCCC2	MCCC2 Entrez, Source	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	2111	0.080	0.4989	Yes
39	ALDH5A1	ALDH5A1 Entrez, Source	aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)	2210	0.077	0.4970	Yes
40	PYGB	PYGB Entrez, Source	phosphorylase, glycogen; brain	2273	0.075	0.4976	Yes
41	EGLN2	EGLN2 Entrez, Source	egl nine homolog 2 (C. elegans)	2331	0.073	0.4985	Yes
42	BNIP3	BNIP3 Entrez, Source	BCL2/adenovirus E1B 19kDa interacting protein 3	2391	0.071	0.4990	Yes
43	CEL	CEL Entrez, Source	carboxyl ester lipase (bile salt-stimulated lipase)	2522	0.067	0.4940	No
44	CPT1B	CPT1B Entrez, Source	carnitine palmitoyltransferase 1B (muscle)	2591	0.065	0.4935	No
45	PRSS2	PRSS2 Entrez, Source	protease, serine, 2 (trypsin 2)	2794	0.060	0.4824	No
46	ANAPC2	ANAPC2 Entrez, Source	anaphase promoting complex subunit 2	2963	0.056	0.4737	No
47	ASL	ASL Entrez, Source	argininosuccinate lyase	3041	0.053	0.4717	No
48	NUDT3	NUDT3 Entrez, Source	nudix (nucleoside diphosphate linked moiety X)-type motif 3	3099	0.052	0.4710	No
49	RNASEH2A	RNASEH2A Entrez, Source	ribonuclease H2, subunit A	3157	0.051	0.4703	No
50	ALDOB	ALDOB Entrez, Source	aldolase B, fructose-bisphosphate	3253	0.048	0.4665	No
51	TPP1	TPP1 Entrez, Source	tripeptidyl peptidase I	3294	0.047	0.4669	No
52	SIAH2	SIAH2 Entrez, Source	seven in absentia homolog 2 (Drosophila)	3372	0.046	0.4643	No
53	CDKN2A	CDKN2A Entrez, Source	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	3401	0.045	0.4654	No
54	UBE4A	UBE4A Entrez, Source	ubiquitination factor E4A (UFD2 homolog, yeast)	3642	0.040	0.4501	No
55	ASPA	ASPA Entrez, Source	aspartoacylase (Canavan disease)	3681	0.039	0.4500	No
56	ISG20	ISG20 Entrez, Source	interferon stimulated exonuclease gene 20kDa	3732	0.038	0.4489	No
57	PDHB	PDHB Entrez, Source	pyruvate dehydrogenase (lipoamide) beta	3755	0.037	0.4499	No
58	SDHD	SDHD Entrez, Source	succinate dehydrogenase complex, subunit D, integral membrane protein	3852	0.036	0.4452	No
59	BCKDK	BCKDK Entrez, Source	branched chain ketoacid dehydrogenase kinase	3853	0.036	0.4477	No
60	DFFA	DFFA Entrez, Source	DNA fragmentation factor, 45kDa, alpha polypeptide	3973	0.033	0.4411	No
61	SDHC	SDHC Entrez, Source	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	4192	0.029	0.4266	No
62	BTRC	BTRC Entrez, Source	beta-transducin repeat containing	4396	0.025	0.4131	No
63	ACADVL	ACADVL Entrez, Source	acyl-Coenzyme A dehydrogenase, very long chain	4485	0.024	0.4081	No
64	ALDH1L1	ALDH1L1 Entrez, Source	aldehyde dehydrogenase 1 family, member L1	4510	0.023	0.4079	No
65	PRDX6	PRDX6 Entrez, Source	peroxiredoxin 6	4787	0.019	0.3884	No
66	HPD	HPD Entrez, Source	4-hydroxyphenylpyruvate dioxygenase	4885	0.017	0.3823	No
67	CYCS	CYCS Entrez, Source	cytochrome c, somatic	4888	0.017	0.3833	No
68	ACADM	ACADM Entrez, Source	acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	4941	0.016	0.3805	No
69	SDHA	SDHA Entrez, Source	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	4953	0.016	0.3808	No
70	AKR1D1	AKR1D1 Entrez, Source	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	5260	0.011	0.3584	No
71	MPST	MPST Entrez, Source	mercaptopyruvate sulfurtransferase	5279	0.010	0.3578	No
72	GBA2	GBA2 Entrez, Source	glucosidase, beta (bile acid) 2	5370	0.009	0.3516	No
73	AMT	AMT Entrez, Source	aminomethyltransferase	5396	0.009	0.3504	No
74	PFKM	PFKM Entrez, Source	phosphofructokinase, muscle	5738	0.004	0.3248	No
75	NEU3	NEU3 Entrez, Source	sialidase 3 (membrane sialidase)	6050	-0.001	0.3013	No
76	SQSTM1	SQSTM1 Entrez, Source	sequestosome 1	6184	-0.003	0.2915	No
77	NPLOC4	NPLOC4 Entrez, Source	nuclear protein localization 4 homolog (S. cerevisiae)	6354	-0.006	0.2791	No
78	HADHB	HADHB Entrez, Source	hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit	6362	-0.006	0.2790	No
79	GCSH	GCSH Entrez, Source	glycine cleavage system protein H (aminomethyl carrier)	6406	-0.006	0.2762	No
80	STUB1	STUB1 Entrez, Source	STIP1 homology and U-box containing protein 1	6444	-0.007	0.2738	No
81	UBB	UBB Entrez, Source	ubiquitin B	6484	-0.007	0.2714	No
82	YWHAH	YWHAH Entrez, Source	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	6649	-0.010	0.2597	No
83	FAF1	FAF1 Entrez, Source	Fas (TNFRSF6) associated factor 1	6848	-0.013	0.2456	No
84	VCP	VCP Entrez, Source	valosin-containing protein	7037	-0.016	0.2325	No
85	ERCC3	ERCC3 Entrez, Source	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	7085	-0.016	0.2301	No
86	GAPDHS	GAPDHS Entrez, Source	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	7146	-0.017	0.2268	No
87	NEDD8	NEDD8 Entrez, Source	neural precursor cell expressed, developmentally down-regulated 8	7156	-0.018	0.2274	No
88	PARK2	PARK2 Entrez, Source	Parkinson disease (autosomal recessive, juvenile) 2, parkin	7304	-0.020	0.2177	No
89	UBE2N	UBE2N Entrez, Source	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	7534	-0.023	0.2020	No
90	SOD1	SOD1 Entrez, Source	superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))	7545	-0.023	0.2029	No
91	ACLY	ACLY Entrez, Source	ATP citrate lyase	7774	-0.027	0.1875	No
92	TREH	TREH Entrez, Source	trehalase (brush-border membrane glycoprotein)	7852	-0.028	0.1837	No
93	PSMC5	PSMC5 Entrez, Source	proteasome (prosome, macropain) 26S subunit, ATPase, 5	7944	-0.030	0.1789	No
94	SYVN1	SYVN1 Entrez, Source	synovial apoptosis inhibitor 1, synoviolin	8081	-0.032	0.1709	No
95	DHPS	DHPS Entrez, Source	deoxyhypusine synthase	8259	-0.035	0.1600	No
96	GOT2	GOT2 Entrez, Source	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)	8497	-0.039	0.1448	No
97	ASRGL1	ASRGL1 Entrez, Source	asparaginase like 1	8649	-0.041	0.1363	No
98	UBE2I	UBE2I Entrez, Source	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	8725	-0.043	0.1337	No
99	FBXO7	FBXO7 Entrez, Source	F-box protein 7	8758	-0.043	0.1343	No
100	ANAPC4	ANAPC4 Entrez, Source	anaphase promoting complex subunit 4	8855	-0.045	0.1303	No
101	INDO	INDO Entrez, Source	indoleamine-pyrrole 2,3 dioxygenase	8856	-0.045	0.1335	No
102	RNASEH1	RNASEH1 Entrez, Source	ribonuclease H1	8861	-0.045	0.1363	No
103	UBE2D3	UBE2D3 Entrez, Source	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	8991	-0.047	0.1299	No
104	UBE2D2	UBE2D2 Entrez, Source	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	9056	-0.048	0.1285	No
105	PPARD	PPARD Entrez, Source	peroxisome proliferative activated receptor, delta	9075	-0.048	0.1306	No
106	USP33	USP33 Entrez, Source	ubiquitin specific peptidase 33	9360	-0.053	0.1129	No
107	CDC23	CDC23 Entrez, Source	CDC23 (cell division cycle 23, yeast, homolog)	9367	-0.054	0.1163	No
108	HGS	HGS Entrez, Source	hepatocyte growth factor-regulated tyrosine kinase substrate	9370	-0.054	0.1199	No
109	TSG101	TSG101 Entrez, Source	tumor susceptibility gene 101	9444	-0.055	0.1183	No
110	UBE2G1	UBE2G1 Entrez, Source	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	9631	-0.058	0.1084	No
111	FBXO22	FBXO22 Entrez, Source	F-box protein 22	9993	-0.066	0.0858	No
112	UBE2A	UBE2A Entrez, Source	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	10509	-0.078	0.0523	No
113	TST	TST Entrez, Source	thiosulfate sulfurtransferase (rhodanese)	10520	-0.078	0.0572	No
114	GSPT1	GSPT1 Entrez, Source	G1 to S phase transition 1	10533	-0.079	0.0618	No
115	BAX	BAX Entrez, Source	BCL2-associated X protein	10615	-0.080	0.0614	No
116	DFFB	DFFB Entrez, Source	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	10724	-0.083	0.0592	No
117	BLVRA	BLVRA Entrez, Source	biliverdin reductase A	11052	-0.092	0.0409	No
118	ABCE1	ABCE1 Entrez, Source	ATP-binding cassette, sub-family E (OABP), member 1	11152	-0.095	0.0402	No
119	UFD1L	UFD1L Entrez, Source	ubiquitin fusion degradation 1 like (yeast)	11173	-0.095	0.0454	No
120	GAD2	GAD2 Entrez, Source	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	11228	-0.096	0.0482	No
121	GAD1	GAD1 Entrez, Source	glutamate decarboxylase 1 (brain, 67kDa)	11300	-0.099	0.0498	No
122	ARIH1	ARIH1 Entrez, Source	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	11547	-0.107	0.0388	No
123	PABPC4	PABPC4 Entrez, Source	poly(A) binding protein, cytoplasmic 4 (inducible form)	11571	-0.108	0.0448	No
124	HNRPD	HNRPD Entrez, Source	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	11613	-0.110	0.0495	No
125	UBE2V2	UBE2V2 Entrez, Source	ubiquitin-conjugating enzyme E2 variant 2	12194	-0.136	0.0153	No
126	CDC20	CDC20 Entrez, Source	CDC20 cell division cycle 20 homolog (S. cerevisiae)	12218	-0.137	0.0233	No
127	PPARA	PPARA Entrez, Source	peroxisome proliferative activated receptor, alpha	12287	-0.141	0.0282	No
128	NUDT5	NUDT5 Entrez, Source	nudix (nucleoside diphosphate linked moiety X)-type motif 5	12409	-0.149	0.0297	No
129	FRAP1	FRAP1 Entrez, Source	FK506 binding protein 12-rapamycin associated protein 1	13090	-0.248	-0.0042	No
130	MDM4	MDM4 Entrez, Source	Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse)	13232	-0.326	0.0083	No