Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetCELLULAR_LIPID_METABOLIC_PROCESS
Enrichment Score (ES)0.49634865
Normalized Enrichment Score (NES)1.8961537
Nominal p-value0.0
FDR q-value0.012944388
FWER p-Value0.626
Table: GSEA Results Summary



Fig 1: Enrichment plot: CELLULAR_LIPID_METABOLIC_PROCESS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LPLLPL
Entrez,  Source
lipoprotein lipase450.6710.0345Yes
2CPT1ACPT1A
Entrez,  Source
carnitine palmitoyltransferase 1A (liver)470.6600.0717Yes
3HAO2HAO2
Entrez,  Source
hydroxyacid oxidase 2 (long chain)540.6300.1068Yes
4SOAT1SOAT1
Entrez,  Source
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1850.5480.1355Yes
5ADMADM
Entrez,  Source
adrenomedullin960.5230.1642Yes
6ECH1ECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal1810.4050.1807Yes
7ST8SIA3ST8SIA3
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 31850.4020.2032Yes
8ABCG1ABCG1
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 11870.4000.2257Yes
9PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 12030.3840.2462Yes
10PLA1APLA1A
Entrez,  Source
phospholipase A1 member A2360.3550.2638Yes
11STSSTS
Entrez,  Source
steroid sulfatase (microsomal), arylsulfatase C, isozyme S2880.3160.2778Yes
12HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 13020.3080.2942Yes
13ACOX2ACOX2
Entrez,  Source
acyl-Coenzyme A oxidase 2, branched chain3790.2690.3036Yes
14SERINC2SERINC2
Entrez,  Source
serine incorporator 23860.2660.3182Yes
15NR0B2NR0B2
Entrez,  Source
nuclear receptor subfamily 0, group B, member 24850.2320.3239Yes
16B4GALNT1B4GALNT1
Entrez,  Source
beta-1,4-N-acetyl-galactosaminyl transferase 15150.2230.3343Yes
17IHPK2IHPK2
Entrez,  Source
inositol hexaphosphate kinase 25360.2190.3451Yes
18ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial5850.2090.3533Yes
19SCARB1SCARB1
Entrez,  Source
scavenger receptor class B, member 16200.2030.3621Yes
20TSPOTSPO
Entrez,  Source
translocator protein (18kDa)6440.1980.3716Yes
21PEMTPEMT
Entrez,  Source
phosphatidylethanolamine N-methyltransferase7080.1840.3772Yes
22MLYCDMLYCD
Entrez,  Source
malonyl-CoA decarboxylase7130.1830.3872Yes
23SCP2SCP2
Entrez,  Source
sterol carrier protein 27260.1810.3965Yes
24RETSATRETSAT
Entrez,  Source
retinol saturase (all-trans-retinol 13,14-reductase)7300.1810.4065Yes
25PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)8100.1680.4100Yes
26HACL1HACL1
Entrez,  Source
2-hydroxyacyl-CoA lyase 18390.1640.4171Yes
27ACOT2ACOT2
Entrez,  Source
acyl-CoA thioesterase 28760.1590.4234Yes
28NR1I2NR1I2
Entrez,  Source
nuclear receptor subfamily 1, group I, member 28910.1570.4312Yes
29PECIPECI
Entrez,  Source
peroxisomal D3,D2-enoyl-CoA isomerase8940.1570.4399Yes
30BAATBAAT
Entrez,  Source
bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)9060.1560.4479Yes
31ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain10250.1450.4471Yes
32ST8SIA1ST8SIA1
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 110420.1420.4539Yes
33APOMAPOM
Entrez,  Source
apolipoprotein M10740.1380.4594Yes
34LYPLA3LYPLA3
Entrez,  Source
lysophospholipase 3 (lysosomal phospholipase A2)10750.1380.4672Yes
35APOA5APOA5
Entrez,  Source
apolipoprotein A-V11260.1340.4709Yes
36PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha11810.1300.4742Yes
37CLN8CLN8
Entrez,  Source
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)11880.1290.4810Yes
38RARRES2RARRES2
Entrez,  Source
retinoic acid receptor responder (tazarotene induced) 211900.1290.4882Yes
39CHPT1CHPT1
Entrez,  Source
choline phosphotransferase 112310.1250.4922Yes
40ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 113100.1190.4930Yes
41SMPD3SMPD3
Entrez,  Source
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)14780.1090.4866Yes
42SMPD2SMPD2
Entrez,  Source
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)15000.1080.4911Yes
43DGAT1DGAT1
Entrez,  Source
diacylglycerol O-acyltransferase homolog 1 (mouse)15290.1060.4950Yes
44DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)16210.1010.4938Yes
45SPHK1SPHK1
Entrez,  Source
sphingosine kinase 118210.0920.4839Yes
46PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 718470.0910.4871Yes
47APOA1APOA1
Entrez,  Source
apolipoprotein A-I18860.0890.4893Yes
48FADS1FADS1
Entrez,  Source
fatty acid desaturase 118870.0890.4943Yes
49PLCD1PLCD1
Entrez,  Source
phospholipase C, delta 119260.0880.4963Yes
50DHRS9DHRS9
Entrez,  Source
dehydrogenase/reductase (SDR family) member 920370.0840.4927No
51ADIPOR1ADIPOR1
Entrez,  Source
adiponectin receptor 121810.0780.4863No
52ALDH5A1ALDH5A1
Entrez,  Source
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)22100.0770.4885No
53LTA4HLTA4H
Entrez,  Source
leukotriene A4 hydrolase22560.0750.4893No
54CYP19A1CYP19A1
Entrez,  Source
cytochrome P450, family 19, subfamily A, polypeptide 124600.0690.4779No
55FAAHFAAH
Entrez,  Source
fatty acid amide hydrolase24840.0690.4800No
56CELCEL
Entrez,  Source
carboxyl ester lipase (bile salt-stimulated lipase)25220.0670.4810No
57CPT1BCPT1B
Entrez,  Source
carnitine palmitoyltransferase 1B (muscle)25910.0650.4795No
58PSAPPSAP
Entrez,  Source
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)26420.0640.4793No
59UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase27790.0610.4724No
60AGPAT1AGPAT1
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)28130.0600.4733No
61DPM2DPM2
Entrez,  Source
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit29090.0570.4693No
62PIGSPIGS
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class S30590.0530.4610No
63PIGKPIGK
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class K31150.0510.4597No
64GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase31450.0510.4604No
65ABCD2ABCD2
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 231590.0510.4623No
66APOC3APOC3
Entrez,  Source
apolipoprotein C-III31720.0500.4642No
67GPX4GPX4
Entrez,  Source
glutathione peroxidase 4 (phospholipid hydroperoxidase)31900.0500.4657No
68PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A32160.0490.4666No
69NPC2NPC2
Entrez,  Source
Niemann-Pick disease, type C232370.0490.4678No
70ADIPOR2ADIPOR2
Entrez,  Source
adiponectin receptor 232610.0480.4688No
71ST6GALNAC6ST6GALNAC6
Entrez,  Source
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 633070.0470.4680No
72PLA2G5PLA2G5
Entrez,  Source
phospholipase A2, group V36910.0390.4412No
73IHPK1IHPK1
Entrez,  Source
inositol hexaphosphate kinase 137350.0380.4401No
74FDPSFDPS
Entrez,  Source
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)39020.0350.4294No
75DGAT2DGAT2
Entrez,  Source
diacylglycerol O-acyltransferase homolog 2 (mouse)40920.0310.4169No
76SULT2A1SULT2A1
Entrez,  Source
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 143520.0260.3987No
77SERINC1SERINC1
Entrez,  Source
serine incorporator 144420.0250.3934No
78ACADVLACADVL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, very long chain44850.0240.3915No
79BMP6BMP6
Entrez,  Source
bone morphogenetic protein 644980.0230.3919No
80PRDX6PRDX6
Entrez,  Source
peroxiredoxin 647870.0190.3711No
81TNFRSF1ATNFRSF1A
Entrez,  Source
tumor necrosis factor receptor superfamily, member 1A48250.0180.3693No
82ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain49410.0160.3615No
83CROTCROT
Entrez,  Source
carnitine O-octanoyltransferase50090.0150.3573No
84CYP11A1CYP11A1
Entrez,  Source
cytochrome P450, family 11, subfamily A, polypeptide 150930.0140.3518No
85PLA2G6PLA2G6
Entrez,  Source
phospholipase A2, group VI (cytosolic, calcium-independent)51210.0130.3505No
86AKR1D1AKR1D1
Entrez,  Source
aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)52600.0110.3406No
87NSDHLNSDHL
Entrez,  Source
NAD(P) dependent steroid dehydrogenase-like53150.0100.3371No
88GBA2GBA2
Entrez,  Source
glucosidase, beta (bile acid) 253700.0090.3335No
89B4GALT4B4GALT4
Entrez,  Source
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 454030.0090.3316No
90PI4K2A56600.0050.3124No
91HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)57280.0040.3076No
92CYP7B1CYP7B1
Entrez,  Source
cytochrome P450, family 7, subfamily B, polypeptide 158620.0020.2976No
93MBTPS2MBTPS2
Entrez,  Source
membrane-bound transcription factor peptidase, site 259650.0010.2899No
94CD81CD81
Entrez,  Source
CD81 molecule6049-0.0010.2836No
95NEU3NEU3
Entrez,  Source
sialidase 3 (membrane sialidase)6050-0.0010.2837No
96IMPA1IMPA1
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 16056-0.0010.2833No
97HSD3B7HSD3B7
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 76084-0.0010.2814No
98ACOT12ACOT12
Entrez,  Source
acyl-CoA thioesterase 126086-0.0010.2814No
99SERINC5SERINC5
Entrez,  Source
serine incorporator 56205-0.0030.2726No
100PTGS1PTGS1
Entrez,  Source
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)6341-0.0050.2627No
101PTGESPTGES
Entrez,  Source
prostaglandin E synthase6358-0.0060.2618No
102HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit6362-0.0060.2619No
103PIGCPIGC
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class C6374-0.0060.2614No
104STUB1STUB1
Entrez,  Source
STIP1 homology and U-box containing protein 16444-0.0070.2565No
105PNLIPRP2PNLIPRP2
Entrez,  Source
pancreatic lipase-related protein 26579-0.0090.2469No
106YWHAHYWHAH
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide6649-0.0100.2422No
107BRCA1BRCA1
Entrez,  Source
breast cancer 1, early onset6790-0.0120.2323No
108HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 26935-0.0140.2221No
109SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)6999-0.0150.2182No
110ST8SIA5ST8SIA5
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 57111-0.0170.2107No
111FDXRFDXR
Entrez,  Source
ferredoxin reductase7264-0.0190.2003No
112SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7545-0.0230.1804No
113PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)7649-0.0250.1740No
114DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase7755-0.0270.1675No
115PLCB2PLCB2
Entrez,  Source
phospholipase C, beta 27765-0.0270.1684No
116MVKMVK
Entrez,  Source
mevalonate kinase (mevalonic aciduria)7967-0.0300.1548No
117AGPAT6AGPAT6
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)7969-0.0300.1565No
118LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase8062-0.0320.1513No
119AKR1B10AKR1B10
Entrez,  Source
aldo-keto reductase family 1, member B10 (aldose reductase)8074-0.0320.1523No
120PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)8146-0.0330.1487No
121PCYT2PCYT2
Entrez,  Source
phosphate cytidylyltransferase 2, ethanolamine8300-0.0360.1392No
122PCYT1BPCYT1B
Entrez,  Source
phosphate cytidylyltransferase 1, choline, beta8490-0.0390.1270No
123ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 68734-0.0430.1110No
124SPTLC1SPTLC1
Entrez,  Source
serine palmitoyltransferase, long chain base subunit 18793-0.0440.1091No
125PIP5K1APIP5K1A
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha8843-0.0440.1079No
126PPARDPPARD
Entrez,  Source
peroxisome proliferative activated receptor, delta9075-0.0480.0931No
127FADS2FADS2
Entrez,  Source
fatty acid desaturase 29436-0.0550.0689No
128CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)9743-0.0610.0491No
129ASAH2ASAH2
Entrez,  Source
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 29850-0.0630.0446No
130HDLBPHDLBP
Entrez,  Source
high density lipoprotein binding protein (vigilin)9866-0.0640.0471No
131RDH11RDH11
Entrez,  Source
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)10402-0.0750.0108No
132NR0B1NR0B1
Entrez,  Source
nuclear receptor subfamily 0, group B, member 110457-0.0770.0110No
133ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain10528-0.0780.0101No
134CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 210574-0.0790.0112No
135ACOX3ACOX3
Entrez,  Source
acyl-Coenzyme A oxidase 3, pristanoyl11075-0.092-0.0215No
136DHCR7DHCR7
Entrez,  Source
7-dehydrocholesterol reductase11141-0.094-0.0211No
137IL4IL4
Entrez,  Source
interleukin 411204-0.096-0.0204No
138PLA2G2DPLA2G2D
Entrez,  Source
phospholipase A2, group IID11529-0.107-0.0390No
139DHRS3DHRS3
Entrez,  Source
dehydrogenase/reductase (SDR family) member 311541-0.107-0.0338No
140PTENPTEN
Entrez,  Source
phosphatase and tensin homolog (mutated in multiple advanced cancers 1)11578-0.108-0.0304No
141NR1H4NR1H4
Entrez,  Source
nuclear receptor subfamily 1, group H, member 411597-0.109-0.0256No
142MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)11668-0.112-0.0246No
143CNBPCNBP
Entrez,  Source
CCHC-type zinc finger, nucleic acid binding protein11687-0.113-0.0196No
144ST6GALNAC4ST6GALNAC4
Entrez,  Source
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 411914-0.122-0.0298No
145SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11986-0.126-0.0281No
146PLAAPLAA
Entrez,  Source
phospholipase A2-activating protein12215-0.137-0.0376No
147PPARAPPARA
Entrez,  Source
peroxisome proliferative activated receptor, alpha12287-0.141-0.0350No
148IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 112532-0.157-0.0447No
149SGPL1SGPL1
Entrez,  Source
sphingosine-1-phosphate lyase 112660-0.169-0.0447No
150PIGVPIGV
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class V12852-0.192-0.0484No
151GNPATGNPAT
Entrez,  Source
glyceronephosphate O-acyltransferase12982-0.215-0.0460No
152AGPSAGPS
Entrez,  Source
alkylglycerone phosphate synthase13060-0.237-0.0385No
153SLC27A5SLC27A5
Entrez,  Source
solute carrier family 27 (fatty acid transporter), member 513297-0.441-0.0315No
154CD74CD74
Entrez,  Source
CD74 molecule, major histocompatibility complex, class II invariant chain13325-0.6170.0013No
Table: GSEA details [plain text format]



Fig 2: CELLULAR_LIPID_METABOLIC_PROCESS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CELLULAR_LIPID_METABOLIC_PROCESS: Random ES distribution   
Gene set null distribution of ES for CELLULAR_LIPID_METABOLIC_PROCESS