Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | CELL_CYCLE_CHECKPOINT |
| Enrichment Score (ES) | -0.5127264 |
| Normalized Enrichment Score (NES) | -1.3374044 |
| Nominal p-value | 0.13293651 |
| FDR q-value | 0.41343513 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 329 | 0.291 | 0.1555 | No |
| 2 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 3116 | 0.051 | -0.0216 | No |
| 3 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 5310 | 0.010 | -0.1799 | No |
| 4 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 5837 | 0.002 | -0.2179 | No |
| 5 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 6274 | -0.004 | -0.2480 | No |
| 6 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 6790 | -0.012 | -0.2792 | No |
| 7 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8469 | -0.038 | -0.3813 | No |
| 8 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 8735 | -0.043 | -0.3746 | No |
| 9 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 8812 | -0.044 | -0.3530 | No |
| 10 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 10152 | -0.069 | -0.4105 | Yes |
| 11 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 10679 | -0.082 | -0.3992 | Yes |
| 12 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11337 | -0.100 | -0.3865 | Yes |
| 13 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.3744 | Yes |
| 14 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | -0.1998 | Yes |
| 15 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13244 | -0.339 | 0.0074 | Yes |
