Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CHANG_SERUM_RESPONSE_DN |
| Enrichment Score (ES) | 0.60359657 |
| Normalized Enrichment Score (NES) | 2.0906768 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0013475447 |
| FWER p-Value | 0.039 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 28 | 0.756 | 0.0740 | Yes |
| 2 | MAF | MAF Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 43 | 0.675 | 0.1410 | Yes |
| 3 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 149 | 0.447 | 0.1781 | Yes |
| 4 | PGCP | PGCP Entrez, Source | - | 183 | 0.404 | 0.2163 | Yes |
| 5 | JAG1 | JAG1 Entrez, Source | jagged 1 (Alagille syndrome) | 222 | 0.366 | 0.2503 | Yes |
| 6 | DPP7 | DPP7 Entrez, Source | dipeptidyl-peptidase 7 | 268 | 0.329 | 0.2801 | Yes |
| 7 | CLIC2 | CLIC2 Entrez, Source | chloride intracellular channel 2 | 304 | 0.304 | 0.3081 | Yes |
| 8 | SLC5A3 | SLC5A3 Entrez, Source | solute carrier family 5 (inositol transporters), member 3 | 333 | 0.289 | 0.3352 | Yes |
| 9 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 354 | 0.280 | 0.3619 | Yes |
| 10 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 394 | 0.263 | 0.3854 | Yes |
| 11 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 404 | 0.258 | 0.4107 | Yes |
| 12 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 450 | 0.245 | 0.4320 | Yes |
| 13 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 483 | 0.233 | 0.4531 | Yes |
| 14 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 538 | 0.219 | 0.4711 | Yes |
| 15 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 630 | 0.201 | 0.4844 | Yes |
| 16 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 722 | 0.182 | 0.4959 | Yes |
| 17 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 843 | 0.163 | 0.5033 | Yes |
| 18 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 846 | 0.163 | 0.5196 | Yes |
| 19 | SLC40A1 | SLC40A1 Entrez, Source | solute carrier family 40 (iron-regulated transporter), member 1 | 870 | 0.160 | 0.5339 | Yes |
| 20 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 959 | 0.151 | 0.5425 | Yes |
| 21 | FCGRT | FCGRT Entrez, Source | Fc fragment of IgG, receptor, transporter, alpha | 965 | 0.150 | 0.5573 | Yes |
| 22 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 984 | 0.148 | 0.5709 | Yes |
| 23 | CNTNAP1 | CNTNAP1 Entrez, Source | contactin associated protein 1 | 1143 | 0.133 | 0.5723 | Yes |
| 24 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 1195 | 0.128 | 0.5814 | Yes |
| 25 | CST3 | CST3 Entrez, Source | cystatin C (amyloid angiopathy and cerebral hemorrhage) | 1282 | 0.121 | 0.5872 | Yes |
| 26 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 1723 | 0.096 | 0.5637 | Yes |
| 27 | IGBP1 | IGBP1 Entrez, Source | immunoglobulin (CD79A) binding protein 1 | 1763 | 0.095 | 0.5703 | Yes |
| 28 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1854 | 0.090 | 0.5726 | Yes |
| 29 | PKIG | PKIG Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | 1880 | 0.089 | 0.5798 | Yes |
| 30 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 1887 | 0.089 | 0.5883 | Yes |
| 31 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 1890 | 0.089 | 0.5971 | Yes |
| 32 | AXIN2 | AXIN2 Entrez, Source | axin 2 (conductin, axil) | 1922 | 0.088 | 0.6036 | Yes |
| 33 | CTSF | CTSF Entrez, Source | cathepsin F | 2228 | 0.076 | 0.5883 | No |
| 34 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 2276 | 0.075 | 0.5923 | No |
| 35 | CAMLG | CAMLG Entrez, Source | calcium modulating ligand | 2383 | 0.071 | 0.5915 | No |
| 36 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 2434 | 0.070 | 0.5947 | No |
| 37 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 2524 | 0.067 | 0.5948 | No |
| 38 | WBP2 | WBP2 Entrez, Source | WW domain binding protein 2 | 2622 | 0.064 | 0.5939 | No |
| 39 | SQLE | SQLE Entrez, Source | squalene epoxidase | 3091 | 0.052 | 0.5639 | No |
| 40 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 3235 | 0.049 | 0.5580 | No |
| 41 | APOD | APOD Entrez, Source | apolipoprotein D | 3255 | 0.048 | 0.5614 | No |
| 42 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | 0.5469 | No |
| 43 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 3540 | 0.042 | 0.5486 | No |
| 44 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 3742 | 0.038 | 0.5373 | No |
| 45 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 3902 | 0.035 | 0.5288 | No |
| 46 | LUM | LUM Entrez, Source | lumican | 4533 | 0.023 | 0.4836 | No |
| 47 | CCNL2 | CCNL2 Entrez, Source | cyclin L2 | 5474 | 0.008 | 0.4135 | No |
| 48 | SFTPB | SFTPB Entrez, Source | surfactant, pulmonary-associated protein B | 5569 | 0.006 | 0.4071 | No |
| 49 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 5574 | 0.006 | 0.4074 | No |
| 50 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5704 | 0.004 | 0.3981 | No |
| 51 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 5770 | 0.003 | 0.3935 | No |
| 52 | GLS | GLS Entrez, Source | glutaminase | 5935 | 0.001 | 0.3812 | No |
| 53 | TNFSF12 | TNFSF12 Entrez, Source | tumor necrosis factor (ligand) superfamily, member 12 | 6156 | -0.002 | 0.3649 | No |
| 54 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 6799 | -0.012 | 0.3177 | No |
| 55 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 6856 | -0.013 | 0.3148 | No |
| 56 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 7239 | -0.019 | 0.2879 | No |
| 57 | DNM1 | DNM1 Entrez, Source | dynamin 1 | 7344 | -0.020 | 0.2821 | No |
| 58 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 7513 | -0.023 | 0.2717 | No |
| 59 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7612 | -0.024 | 0.2668 | No |
| 60 | F10 | F10 Entrez, Source | coagulation factor X | 7895 | -0.029 | 0.2484 | No |
| 61 | PTPRU | PTPRU Entrez, Source | protein tyrosine phosphatase, receptor type, U | 8514 | -0.039 | 0.2058 | No |
| 62 | MBP | MBP Entrez, Source | myelin basic protein | 8983 | -0.047 | 0.1753 | No |
| 63 | IL6ST | IL6ST Entrez, Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 9035 | -0.048 | 0.1762 | No |
| 64 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 9436 | -0.055 | 0.1516 | No |
| 65 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 9836 | -0.063 | 0.1279 | No |
| 66 | BBC3 | BBC3 Entrez, Source | BCL2 binding component 3 | 10054 | -0.067 | 0.1183 | No |
| 67 | ZNF219 | ZNF219 Entrez, Source | zinc finger protein 219 | 10238 | -0.071 | 0.1117 | No |
| 68 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 10960 | -0.089 | 0.0664 | No |
| 69 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 11256 | -0.097 | 0.0539 | No |
| 70 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 11376 | -0.101 | 0.0552 | No |
| 71 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 11395 | -0.102 | 0.0641 | No |
| 72 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 11864 | -0.120 | 0.0409 | No |
| 73 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 11986 | -0.126 | 0.0444 | No |
| 74 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 12532 | -0.157 | 0.0192 | No |
| 75 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 12932 | -0.205 | 0.0097 | No |
| 76 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12952 | -0.209 | 0.0294 | No |
