Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
Upregulated in class | double_gel_8d |
GeneSet | CHIARETTI_T_ALL_DIFF |
Enrichment Score (ES) | 0.51306856 |
Normalized Enrichment Score (NES) | 1.987434 |
Nominal p-value | 0.0 |
FDR q-value | 0.00509819 |
FWER p-Value | 0.24 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | IGFBP7 | IGFBP7 Entrez,  Source | insulin-like growth factor binding protein 7 | 2 | 1.254 | 0.0593 | Yes |
2 | FOS | FOS Entrez,  Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 9 | 0.936 | 0.1033 | Yes |
3 | CCND2 | CCND2 Entrez,  Source | cyclin D2 | 10 | 0.885 | 0.1453 | Yes |
4 | ANXA1 | ANXA1 Entrez,  Source | annexin A1 | 11 | 0.884 | 0.1872 | Yes |
5 | ARMCX2 | ARMCX2 Entrez,  Source | armadillo repeat containing, X-linked 2 | 20 | 0.787 | 0.2239 | Yes |
6 | RGS2 | RGS2 Entrez,  Source | regulator of G-protein signalling 2, 24kDa | 25 | 0.771 | 0.2602 | Yes |
7 | MAF | MAF Entrez,  Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 43 | 0.675 | 0.2909 | Yes |
8 | LGALS1 | LGALS1 Entrez,  Source | lectin, galactoside-binding, soluble, 1 (galectin 1) | 60 | 0.614 | 0.3188 | Yes |
9 | RGS1 | RGS1 Entrez,  Source | regulator of G-protein signalling 1 | 75 | 0.565 | 0.3445 | Yes |
10 | CXCL2 | CXCL2 Entrez,  Source | chemokine (C-X-C motif) ligand 2 | 138 | 0.458 | 0.3615 | Yes |
11 | SERPINE2 | SERPINE2 Entrez,  Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 140 | 0.455 | 0.3831 | Yes |
12 | AHNAK | AHNAK Entrez,  Source | AHNAK nucleoprotein (desmoyokin) | 255 | 0.338 | 0.3904 | Yes |
13 | TSC22D3 | TSC22D3 Entrez,  Source | TSC22 domain family, member 3 | 286 | 0.317 | 0.4032 | Yes |
14 | ATF3 | ATF3 Entrez,  Source | activating transcription factor 3 | 310 | 0.299 | 0.4156 | Yes |
15 | TFPI | TFPI Entrez,  Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 316 | 0.294 | 0.4292 | Yes |
16 | CCL3 | CCL3 Entrez,  Source | chemokine (C-C motif) ligand 3 | 353 | 0.281 | 0.4398 | Yes |
17 | PTGER4 | PTGER4 Entrez,  Source | prostaglandin E receptor 4 (subtype EP4) | 402 | 0.258 | 0.4484 | Yes |
18 | PF4 | PF4 Entrez,  Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 506 | 0.226 | 0.4513 | Yes |
19 | SELENBP1 | SELENBP1 Entrez,  Source | selenium binding protein 1 | 538 | 0.219 | 0.4593 | Yes |
20 | ALCAM | ALCAM Entrez,  Source | activated leukocyte cell adhesion molecule | 539 | 0.219 | 0.4697 | Yes |
21 | PLAGL1 | PLAGL1 Entrez,  Source | pleiomorphic adenoma gene-like 1 | 576 | 0.211 | 0.4770 | Yes |
22 | EMP3 | EMP3 Entrez,  Source | epithelial membrane protein 3 | 755 | 0.176 | 0.4718 | Yes |
23 | SPRY2 | SPRY2 Entrez,  Source | sprouty homolog 2 (Drosophila) | 784 | 0.172 | 0.4779 | Yes |
24 | LMO4 | LMO4 Entrez,  Source | LIM domain only 4 | 808 | 0.169 | 0.4841 | Yes |
25 | PTTG1IP | PTTG1IP Entrez,  Source | pituitary tumor-transforming 1 interacting protein | 811 | 0.168 | 0.4919 | Yes |
26 | PDLIM1 | PDLIM1 Entrez,  Source | PDZ and LIM domain 1 (elfin) | 957 | 0.151 | 0.4881 | Yes |
27 | S100A8 | S100A8 Entrez,  Source | S100 calcium binding protein A8 | 960 | 0.151 | 0.4951 | Yes |
28 | S100A4 | S100A4 Entrez,  Source | S100 calcium binding protein A4 | 962 | 0.151 | 0.5022 | Yes |
29 | IFRD1 | IFRD1 Entrez,  Source | interferon-related developmental regulator 1 | 999 | 0.147 | 0.5064 | Yes |
30 | ANXA5 | ANXA5 Entrez,  Source | annexin A5 | 1191 | 0.129 | 0.4980 | Yes |
31 | ACTA1 | ACTA1 Entrez,  Source | actin, alpha 1, skeletal muscle | 1218 | 0.126 | 0.5021 | Yes |
32 | DUSP1 | DUSP1 Entrez,  Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.5047 | Yes |
33 | NID2 | NID2 Entrez,  Source | nidogen 2 (osteonidogen) | 1349 | 0.116 | 0.5036 | Yes |
34 | DUSP6 | DUSP6 Entrez,  Source | dual specificity phosphatase 6 | 1504 | 0.108 | 0.4971 | Yes |
35 | PLK2 | PLK2 Entrez,  Source | polo-like kinase 2 (Drosophila) | 1523 | 0.107 | 0.5008 | Yes |
36 | ADFP | ADFP Entrez,  Source | adipose differentiation-related protein | 1626 | 0.101 | 0.4978 | Yes |
37 | RUNX3 | RUNX3 Entrez,  Source | runt-related transcription factor 3 | 1657 | 0.100 | 0.5003 | Yes |
38 | PRKCA | PRKCA Entrez,  Source | protein kinase C, alpha | 1663 | 0.099 | 0.5046 | Yes |
39 | PTPRE | PTPRE Entrez,  Source | protein tyrosine phosphatase, receptor type, E | 1672 | 0.099 | 0.5087 | Yes |
40 | HES1 | HES1 Entrez,  Source | hairy and enhancer of split 1, (Drosophila) | 1677 | 0.098 | 0.5131 | Yes |
41 | TLE4 | TLE4 Entrez,  Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1841 | 0.091 | 0.5050 | No |
42 | CXADR | CXADR Entrez,  Source | coxsackie virus and adenovirus receptor | 1853 | 0.090 | 0.5085 | No |
43 | PRSS1 | PRSS1 Entrez,  Source | protease, serine, 1 (trypsin 1) | 1903 | 0.089 | 0.5090 | No |
44 | ALAS2 | ALAS2 Entrez,  Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2058 | 0.083 | 0.5012 | No |
45 | CTBP2 | CTBP2 Entrez,  Source | C-terminal binding protein 2 | 2137 | 0.079 | 0.4991 | No |
46 | SNF1LK | SNF1LK Entrez,  Source | SNF1-like kinase | 2345 | 0.073 | 0.4868 | No |
47 | ACSL1 | ACSL1 Entrez,  Source | acyl-CoA synthetase long-chain family member 1 | 2355 | 0.072 | 0.4896 | No |
48 | CDKN1B | CDKN1B Entrez,  Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2499 | 0.068 | 0.4820 | No |
49 | CTSH | CTSH Entrez,  Source | cathepsin H | 2723 | 0.062 | 0.4680 | No |
50 | DUSP2 | DUSP2 Entrez,  Source | dual specificity phosphatase 2 | 2724 | 0.062 | 0.4709 | No |
51 | UGCG | UGCG Entrez,  Source | UDP-glucose ceramide glucosyltransferase | 2779 | 0.061 | 0.4697 | No |
52 | BIRC3 | BIRC3 Entrez,  Source | baculoviral IAP repeat-containing 3 | 2803 | 0.060 | 0.4708 | No |
53 | CEBPB | CEBPB Entrez,  Source | CCAAT/enhancer binding protein (C/EBP), beta | 2848 | 0.059 | 0.4703 | No |
54 | MINPP1 | MINPP1 Entrez,  Source | multiple inositol polyphosphate histidine phosphatase, 1 | 2918 | 0.057 | 0.4677 | No |
55 | ITPR3 | ITPR3 Entrez,  Source | inositol 1,4,5-triphosphate receptor, type 3 | 2923 | 0.057 | 0.4701 | No |
56 | S100A10 | S100A10 Entrez,  Source | S100 calcium binding protein A10 | 2981 | 0.055 | 0.4684 | No |
57 | MAL | MAL Entrez,  Source | mal, T-cell differentiation protein | 3112 | 0.052 | 0.4610 | No |
58 | GAB2 | GAB2 Entrez,  Source | GRB2-associated binding protein 2 | 3334 | 0.046 | 0.4465 | No |
59 | FRMD4B | FRMD4B Entrez,  Source | FERM domain containing 4B | 3422 | 0.045 | 0.4420 | No |
60 | SOCS2 | SOCS2 Entrez,  Source | suppressor of cytokine signaling 2 | 3428 | 0.044 | 0.4437 | No |
61 | ISG20 | ISG20 Entrez,  Source | interferon stimulated exonuclease gene 20kDa | 3732 | 0.038 | 0.4226 | No |
62 | CD69 | CD69 Entrez,  Source | CD69 molecule | 4095 | 0.031 | 0.3966 | No |
63 | BCL11A | BCL11A Entrez,  Source | B-cell CLL/lymphoma 11A (zinc finger protein) | 4147 | 0.030 | 0.3941 | No |
64 | FHL1 | FHL1 Entrez,  Source | four and a half LIM domains 1 | 4269 | 0.028 | 0.3863 | No |
65 | EPHB6 | EPHB6 Entrez,  Source | EPH receptor B6 | 4295 | 0.027 | 0.3857 | No |
66 | IFI30 | IFI30 Entrez,  Source | interferon, gamma-inducible protein 30 | 4301 | 0.027 | 0.3866 | No |
67 | CD97 | CD97 Entrez,  Source | CD97 molecule | 4342 | 0.026 | 0.3848 | No |
68 | TRH | TRH Entrez,  Source | thyrotropin-releasing hormone | 4399 | 0.025 | 0.3818 | No |
69 | HIST1H2BL | HIST1H2BL Entrez,  Source | histone cluster 1, H2bl | 4424 | 0.025 | 0.3812 | No |
70 | IL4R | IL4R Entrez,  Source | interleukin 4 receptor | 4494 | 0.024 | 0.3771 | No |
71 | WASF1 | WASF1 Entrez,  Source | WAS protein family, member 1 | 4524 | 0.023 | 0.3759 | No |
72 | STK17B | STK17B Entrez,  Source | serine/threonine kinase 17b (apoptosis-inducing) | 4570 | 0.022 | 0.3736 | No |
73 | ALOX5 | ALOX5 Entrez,  Source | arachidonate 5-lipoxygenase | 4658 | 0.021 | 0.3680 | No |
74 | BUB1B | BUB1B Entrez,  Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 4680 | 0.020 | 0.3673 | No |
75 | NOTCH3 | NOTCH3 Entrez,  Source | Notch homolog 3 (Drosophila) | 4689 | 0.020 | 0.3677 | No |
76 | TSHR | TSHR Entrez,  Source | thyroid stimulating hormone receptor | 4846 | 0.018 | 0.3567 | No |
77 | ZBTB16 | ZBTB16 Entrez,  Source | zinc finger and BTB domain containing 16 | 5042 | 0.014 | 0.3426 | No |
78 | GUCY1A3 | GUCY1A3 Entrez,  Source | guanylate cyclase 1, soluble, alpha 3 | 5232 | 0.011 | 0.3288 | No |
79 | CDC42 | CDC42 Entrez,  Source | cell division cycle 42 (GTP binding protein, 25kDa) | 5548 | 0.007 | 0.3053 | No |
80 | PRDX2 | PRDX2 Entrez,  Source | peroxiredoxin 2 | 5562 | 0.006 | 0.3046 | No |
81 | LDLR | LDLR Entrez,  Source | low density lipoprotein receptor (familial hypercholesterolemia) | 5574 | 0.006 | 0.3040 | No |
82 | CASP8 | CASP8 Entrez,  Source | caspase 8, apoptosis-related cysteine peptidase | 5583 | 0.006 | 0.3037 | No |
83 | SCG2 | SCG2 Entrez,  Source | secretogranin II (chromogranin C) | 5614 | 0.005 | 0.3017 | No |
84 | STAT1 | STAT1 Entrez,  Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | 0.2968 | No |
85 | HPGD | HPGD Entrez,  Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 5728 | 0.004 | 0.2936 | No |
86 | SLC4A1 | SLC4A1 Entrez,  Source | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 5762 | 0.003 | 0.2913 | No |
87 | FXYD2 | FXYD2 Entrez,  Source | FXYD domain containing ion transport regulator 2 | 5938 | 0.001 | 0.2780 | No |
88 | CAT | CAT Entrez,  Source | catalase | 6311 | -0.005 | 0.2501 | No |
89 | AQP3 | AQP3 Entrez,  Source | aquaporin 3 (Gill blood group) | 6430 | -0.007 | 0.2415 | No |
90 | NFIL3 | NFIL3 Entrez,  Source | nuclear factor, interleukin 3 regulated | 6595 | -0.009 | 0.2295 | No |
91 | ID3 | ID3 Entrez,  Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | 0.2234 | No |
92 | ARID5A | ARID5A Entrez,  Source | AT rich interactive domain 5A (MRF1-like) | 6737 | -0.011 | 0.2199 | No |
93 | CDKN2C | CDKN2C Entrez,  Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7011 | -0.015 | 0.1999 | No |
94 | MX1 | MX1 Entrez,  Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 7189 | -0.018 | 0.1873 | No |
95 | PPBP | PPBP Entrez,  Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 7274 | -0.019 | 0.1819 | No |
96 | CD2 | CD2 Entrez,  Source | CD2 molecule | 7323 | -0.020 | 0.1792 | No |
97 | ALDH1A2 | ALDH1A2 Entrez,  Source | aldehyde dehydrogenase 1 family, member A2 | 7402 | -0.021 | 0.1743 | No |
98 | ID1 | ID1 Entrez,  Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 7557 | -0.023 | 0.1637 | No |
99 | CD200 | CD200 Entrez,  Source | CD200 molecule | 7585 | -0.024 | 0.1628 | No |
100 | IL12A | IL12A Entrez,  Source | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 7646 | -0.025 | 0.1594 | No |
101 | IRF7 | IRF7 Entrez,  Source | interferon regulatory factor 7 | 7693 | -0.026 | 0.1572 | No |
102 | LAPTM4B | LAPTM4B Entrez,  Source | lysosomal associated protein transmembrane 4 beta | 8069 | -0.032 | 0.1303 | No |
103 | SPON1 | SPON1 Entrez,  Source | spondin 1, extracellular matrix protein | 8114 | -0.032 | 0.1285 | No |
104 | MGAT5 | MGAT5 Entrez,  Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 8412 | -0.038 | 0.1077 | No |
105 | HNRPDL | HNRPDL Entrez,  Source | heterogeneous nuclear ribonucleoprotein D-like | 8663 | -0.041 | 0.0907 | No |
106 | LMO2 | LMO2 Entrez,  Source | LIM domain only 2 (rhombotin-like 1) | 8708 | -0.042 | 0.0894 | No |
107 | SLC2A3 | SLC2A3 Entrez,  Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 8829 | -0.044 | 0.0824 | No |
108 | CCL5 | CCL5 Entrez,  Source | chemokine (C-C motif) ligand 5 | 8913 | -0.046 | 0.0783 | No |
109 | LYN | LYN Entrez,  Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 9007 | -0.047 | 0.0735 | No |
110 | RAP2B | RAP2B Entrez,  Source | RAP2B, member of RAS oncogene family | 9009 | -0.047 | 0.0757 | No |
111 | IL6ST | IL6ST Entrez,  Source | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 9035 | -0.048 | 0.0760 | No |
112 | HHEX | HHEX Entrez,  Source | homeobox, hematopoietically expressed | 9234 | -0.051 | 0.0635 | No |
113 | ST18 | ST18 Entrez,  Source | suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein) | 9316 | -0.053 | 0.0598 | No |
114 | SELL | SELL Entrez,  Source | selectin L (lymphocyte adhesion molecule 1) | 9693 | -0.060 | 0.0342 | No |
115 | AHR | AHR Entrez,  Source | aryl hydrocarbon receptor | 9715 | -0.060 | 0.0354 | No |
116 | S100A9 | S100A9 Entrez,  Source | S100 calcium binding protein A9 | 9785 | -0.062 | 0.0331 | No |
117 | PRG1 | PRG1 Entrez,  Source | proteoglycan 1, secretory granule | 10004 | -0.066 | 0.0198 | No |
118 | IGJ | IGJ Entrez,  Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 10022 | -0.067 | 0.0216 | No |
119 | GARNL1 | GARNL1 Entrez,  Source | GTPase activating Rap/RanGAP domain-like 1 | 10028 | -0.067 | 0.0244 | No |
120 | CD52 | CD52 Entrez,  Source | CD52 molecule | 10093 | -0.068 | 0.0228 | No |
121 | ARF6 | ARF6 Entrez,  Source | ADP-ribosylation factor 6 | 10133 | -0.069 | 0.0231 | No |
122 | RASGRP1 | RASGRP1 Entrez,  Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 10196 | -0.070 | 0.0218 | No |
123 | TOB1 | TOB1 Entrez,  Source | transducer of ERBB2, 1 | 10294 | -0.072 | 0.0179 | No |
124 | CLEC11A | CLEC11A Entrez,  Source | C-type lectin domain family 11, member A | 10483 | -0.077 | 0.0073 | No |
125 | MYC | MYC Entrez,  Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | 0.0062 | No |
126 | BHLHB2 | BHLHB2 Entrez,  Source | basic helix-loop-helix domain containing, class B, 2 | 10960 | -0.089 | -0.0208 | No |
127 | FGFR1 | FGFR1 Entrez,  Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 10976 | -0.090 | -0.0176 | No |
128 | RCBTB2 | RCBTB2 Entrez,  Source | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 11303 | -0.099 | -0.0377 | No |
129 | LAT | LAT Entrez,  Source | linker for activation of T cells | 11315 | -0.099 | -0.0338 | No |
130 | ITGA6 | ITGA6 Entrez,  Source | integrin, alpha 6 | 11513 | -0.106 | -0.0437 | No |
131 | CD8A | CD8A Entrez,  Source | CD8a molecule | 11524 | -0.106 | -0.0394 | No |
132 | DDIT4 | DDIT4 Entrez,  Source | DNA-damage-inducible transcript 4 | 11645 | -0.111 | -0.0432 | No |
133 | SC4MOL | SC4MOL Entrez,  Source | sterol-C4-methyl oxidase-like | 11986 | -0.126 | -0.0630 | No |
134 | SKAP2 | SKAP2 Entrez,  Source | src kinase associated phosphoprotein 2 | 12042 | -0.128 | -0.0611 | No |
135 | PCTK2 | PCTK2 Entrez,  Source | PCTAIRE protein kinase 2 | 12183 | -0.136 | -0.0653 | No |
136 | QKI | QKI Entrez,  Source | quaking homolog, KH domain RNA binding (mouse) | 12354 | -0.146 | -0.0712 | No |
137 | HOXA5 | HOXA5 Entrez,  Source | homeobox A5 | 12360 | -0.146 | -0.0647 | No |
138 | CSDA | CSDA Entrez,  Source | cold shock domain protein A | 12392 | -0.148 | -0.0600 | No |
139 | IFI44 | IFI44 Entrez,  Source | interferon-induced protein 44 | 12405 | -0.149 | -0.0539 | No |
140 | KLF10 | KLF10 Entrez,  Source | Kruppel-like factor 10 | 12453 | -0.151 | -0.0502 | No |
141 | GCH1 | GCH1 Entrez,  Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 12523 | -0.156 | -0.0481 | No |
142 | CD44 | CD44 Entrez,  Source | CD44 molecule (Indian blood group) | 12802 | -0.185 | -0.0603 | No |
143 | H1F0 | H1F0 Entrez,  Source | H1 histone family, member 0 | 12841 | -0.191 | -0.0542 | No |
144 | TAP1 | TAP1 Entrez,  Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12854 | -0.192 | -0.0459 | No |
145 | PSPH | PSPH Entrez,  Source | phosphoserine phosphatase | 13062 | -0.238 | -0.0503 | No |
146 | ARNTL | ARNTL Entrez,  Source | aryl hydrocarbon receptor nuclear translocator-like | 13133 | -0.262 | -0.0432 | No |
147 | G0S2 | G0S2 Entrez,  Source | G0/G1switch 2 | 13137 | -0.265 | -0.0309 | No |
148 | USP1 | USP1 Entrez,  Source | ubiquitin specific peptidase 1 | 13158 | -0.275 | -0.0194 | No |
149 | SFPQ | SFPQ Entrez,  Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13213 | -0.310 | -0.0087 | No |
150 | CLIC4 | CLIC4 Entrez,  Source | chloride intracellular channel 4 | 13274 | -0.389 | 0.0052 | No |