Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetCHIARETTI_T_ALL_DIFF
Enrichment Score (ES)0.51306856
Normalized Enrichment Score (NES)1.987434
Nominal p-value0.0
FDR q-value0.00509819
FWER p-Value0.24
Table: GSEA Results Summary



Fig 1: Enrichment plot: CHIARETTI_T_ALL_DIFF   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 721.2540.0593Yes
2FOSFOS
Entrez,  Source
v-fos FBJ murine osteosarcoma viral oncogene homolog90.9360.1033Yes
3CCND2CCND2
Entrez,  Source
cyclin D2100.8850.1453Yes
4ANXA1ANXA1
Entrez,  Source
annexin A1110.8840.1872Yes
5ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 2200.7870.2239Yes
6RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa250.7710.2602Yes
7MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)430.6750.2909Yes
8LGALS1LGALS1
Entrez,  Source
lectin, galactoside-binding, soluble, 1 (galectin 1)600.6140.3188Yes
9RGS1RGS1
Entrez,  Source
regulator of G-protein signalling 1750.5650.3445Yes
10CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 21380.4580.3615Yes
11SERPINE2SERPINE2
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 21400.4550.3831Yes
12AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)2550.3380.3904Yes
13TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 32860.3170.4032Yes
14ATF3ATF3
Entrez,  Source
activating transcription factor 33100.2990.4156Yes
15TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)3160.2940.4292Yes
16CCL3CCL3
Entrez,  Source
chemokine (C-C motif) ligand 33530.2810.4398Yes
17PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)4020.2580.4484Yes
18PF4PF4
Entrez,  Source
platelet factor 4 (chemokine (C-X-C motif) ligand 4)5060.2260.4513Yes
19SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 15380.2190.4593Yes
20ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule5390.2190.4697Yes
21PLAGL1PLAGL1
Entrez,  Source
pleiomorphic adenoma gene-like 15760.2110.4770Yes
22EMP3EMP3
Entrez,  Source
epithelial membrane protein 37550.1760.4718Yes
23SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)7840.1720.4779Yes
24LMO4LMO4
Entrez,  Source
LIM domain only 48080.1690.4841Yes
25PTTG1IPPTTG1IP
Entrez,  Source
pituitary tumor-transforming 1 interacting protein8110.1680.4919Yes
26PDLIM1PDLIM1
Entrez,  Source
PDZ and LIM domain 1 (elfin)9570.1510.4881Yes
27S100A8S100A8
Entrez,  Source
S100 calcium binding protein A89600.1510.4951Yes
28S100A4S100A4
Entrez,  Source
S100 calcium binding protein A49620.1510.5022Yes
29IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 19990.1470.5064Yes
30ANXA5ANXA5
Entrez,  Source
annexin A511910.1290.4980Yes
31ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle12180.1260.5021Yes
32DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112610.1230.5047Yes
33NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)13490.1160.5036Yes
34DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 615040.1080.4971Yes
35PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)15230.1070.5008Yes
36ADFPADFP
Entrez,  Source
adipose differentiation-related protein16260.1010.4978Yes
37RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 316570.1000.5003Yes
38PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha16630.0990.5046Yes
39PTPREPTPRE
Entrez,  Source
protein tyrosine phosphatase, receptor type, E16720.0990.5087Yes
40HES1HES1
Entrez,  Source
hairy and enhancer of split 1, (Drosophila)16770.0980.5131Yes
41TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)18410.0910.5050No
42CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor18530.0900.5085No
43PRSS1PRSS1
Entrez,  Source
protease, serine, 1 (trypsin 1)19030.0890.5090No
44ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)20580.0830.5012No
45CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 221370.0790.4991No
46SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase23450.0730.4868No
47ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 123550.0720.4896No
48CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)24990.0680.4820No
49CTSHCTSH
Entrez,  Source
cathepsin H27230.0620.4680No
50DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 227240.0620.4709No
51UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase27790.0610.4697No
52BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 328030.0600.4708No
53CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta28480.0590.4703No
54MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 129180.0570.4677No
55ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 329230.0570.4701No
56S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1029810.0550.4684No
57MALMAL
Entrez,  Source
mal, T-cell differentiation protein31120.0520.4610No
58GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 233340.0460.4465No
59FRMD4BFRMD4B
Entrez,  Source
FERM domain containing 4B34220.0450.4420No
60SOCS2SOCS2
Entrez,  Source
suppressor of cytokine signaling 234280.0440.4437No
61ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa37320.0380.4226No
62CD69CD69
Entrez,  Source
CD69 molecule40950.0310.3966No
63BCL11ABCL11A
Entrez,  Source
B-cell CLL/lymphoma 11A (zinc finger protein)41470.0300.3941No
64FHL1FHL1
Entrez,  Source
four and a half LIM domains 142690.0280.3863No
65EPHB6EPHB6
Entrez,  Source
EPH receptor B642950.0270.3857No
66IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3043010.0270.3866No
67CD97CD97
Entrez,  Source
CD97 molecule43420.0260.3848No
68TRHTRH
Entrez,  Source
thyrotropin-releasing hormone43990.0250.3818No
69HIST1H2BLHIST1H2BL
Entrez,  Source
histone cluster 1, H2bl44240.0250.3812No
70IL4RIL4R
Entrez,  Source
interleukin 4 receptor44940.0240.3771No
71WASF1WASF1
Entrez,  Source
WAS protein family, member 145240.0230.3759No
72STK17BSTK17B
Entrez,  Source
serine/threonine kinase 17b (apoptosis-inducing)45700.0220.3736No
73ALOX5ALOX5
Entrez,  Source
arachidonate 5-lipoxygenase46580.0210.3680No
74BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)46800.0200.3673No
75NOTCH3NOTCH3
Entrez,  Source
Notch homolog 3 (Drosophila)46890.0200.3677No
76TSHRTSHR
Entrez,  Source
thyroid stimulating hormone receptor48460.0180.3567No
77ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1650420.0140.3426No
78GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 352320.0110.3288No
79CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)55480.0070.3053No
80PRDX2PRDX2
Entrez,  Source
peroxiredoxin 255620.0060.3046No
81LDLRLDLR
Entrez,  Source
low density lipoprotein receptor (familial hypercholesterolemia)55740.0060.3040No
82CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase55830.0060.3037No
83SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)56140.0050.3017No
84STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa56820.0050.2968No
85HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)57280.0040.2936No
86SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)57620.0030.2913No
87FXYD2FXYD2
Entrez,  Source
FXYD domain containing ion transport regulator 259380.0010.2780No
88CATCAT
Entrez,  Source
catalase6311-0.0050.2501No
89AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)6430-0.0070.2415No
90NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated6595-0.0090.2295No
91ID3ID3
Entrez,  Source
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein6682-0.0100.2234No
92ARID5AARID5A
Entrez,  Source
AT rich interactive domain 5A (MRF1-like)6737-0.0110.2199No
93CDKN2CCDKN2C
Entrez,  Source
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)7011-0.0150.1999No
94MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)7189-0.0180.1873No
95PPBPPPBP
Entrez,  Source
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)7274-0.0190.1819No
96CD2CD2
Entrez,  Source
CD2 molecule7323-0.0200.1792No
97ALDH1A2ALDH1A2
Entrez,  Source
aldehyde dehydrogenase 1 family, member A27402-0.0210.1743No
98ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein7557-0.0230.1637No
99CD200CD200
Entrez,  Source
CD200 molecule7585-0.0240.1628No
100IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)7646-0.0250.1594No
101IRF7IRF7
Entrez,  Source
interferon regulatory factor 77693-0.0260.1572No
102LAPTM4BLAPTM4B
Entrez,  Source
lysosomal associated protein transmembrane 4 beta8069-0.0320.1303No
103SPON1SPON1
Entrez,  Source
spondin 1, extracellular matrix protein8114-0.0320.1285No
104MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase8412-0.0380.1077No
105HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like8663-0.0410.0907No
106LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)8708-0.0420.0894No
107SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 38829-0.0440.0824No
108CCL5CCL5
Entrez,  Source
chemokine (C-C motif) ligand 58913-0.0460.0783No
109LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog9007-0.0470.0735No
110RAP2BRAP2B
Entrez,  Source
RAP2B, member of RAS oncogene family9009-0.0470.0757No
111IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)9035-0.0480.0760No
112HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed9234-0.0510.0635No
113ST18ST18
Entrez,  Source
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)9316-0.0530.0598No
114SELLSELL
Entrez,  Source
selectin L (lymphocyte adhesion molecule 1)9693-0.0600.0342No
115AHRAHR
Entrez,  Source
aryl hydrocarbon receptor9715-0.0600.0354No
116S100A9S100A9
Entrez,  Source
S100 calcium binding protein A99785-0.0620.0331No
117PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule10004-0.0660.0198No
118IGJIGJ
Entrez,  Source
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides10022-0.0670.0216No
119GARNL1GARNL1
Entrez,  Source
GTPase activating Rap/RanGAP domain-like 110028-0.0670.0244No
120CD52CD52
Entrez,  Source
CD52 molecule10093-0.0680.0228No
121ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 610133-0.0690.0231No
122RASGRP1RASGRP1
Entrez,  Source
RAS guanyl releasing protein 1 (calcium and DAG-regulated)10196-0.0700.0218No
123TOB1TOB1
Entrez,  Source
transducer of ERBB2, 110294-0.0720.0179No
124CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A10483-0.0770.0073No
125MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)10547-0.0790.0062No
126BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 210960-0.089-0.0208No
127FGFR1FGFR1
Entrez,  Source
fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)10976-0.090-0.0176No
128RCBTB2RCBTB2
Entrez,  Source
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 211303-0.099-0.0377No
129LATLAT
Entrez,  Source
linker for activation of T cells11315-0.099-0.0338No
130ITGA6ITGA6
Entrez,  Source
integrin, alpha 611513-0.106-0.0437No
131CD8ACD8A
Entrez,  Source
CD8a molecule11524-0.106-0.0394No
132DDIT4DDIT4
Entrez,  Source
DNA-damage-inducible transcript 411645-0.111-0.0432No
133SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11986-0.126-0.0630No
134SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 212042-0.128-0.0611No
135PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 212183-0.136-0.0653No
136QKIQKI
Entrez,  Source
quaking homolog, KH domain RNA binding (mouse)12354-0.146-0.0712No
137HOXA5HOXA5
Entrez,  Source
homeobox A512360-0.146-0.0647No
138CSDACSDA
Entrez,  Source
cold shock domain protein A12392-0.148-0.0600No
139IFI44IFI44
Entrez,  Source
interferon-induced protein 4412405-0.149-0.0539No
140KLF10KLF10
Entrez,  Source
Kruppel-like factor 1012453-0.151-0.0502No
141GCH1GCH1
Entrez,  Source
GTP cyclohydrolase 1 (dopa-responsive dystonia)12523-0.156-0.0481No
142CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)12802-0.185-0.0603No
143H1F0H1F0
Entrez,  Source
H1 histone family, member 012841-0.191-0.0542No
144TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)12854-0.192-0.0459No
145PSPHPSPH
Entrez,  Source
phosphoserine phosphatase13062-0.238-0.0503No
146ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like13133-0.262-0.0432No
147G0S2G0S2
Entrez,  Source
G0/G1switch 213137-0.265-0.0309No
148USP1USP1
Entrez,  Source
ubiquitin specific peptidase 113158-0.275-0.0194No
149SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)13213-0.310-0.0087No
150CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 413274-0.3890.0052No
Table: GSEA details [plain text format]



Fig 2: CHIARETTI_T_ALL_DIFF   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CHIARETTI_T_ALL_DIFF: Random ES distribution   
Gene set null distribution of ES for CHIARETTI_T_ALL_DIFF