Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | CMV_24HRS_DN |
| Enrichment Score (ES) | 0.6598988 |
| Normalized Enrichment Score (NES) | 2.1852982 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.7058574E-4 |
| FWER p-Value | 0.0050 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 6 | 1.154 | 0.1323 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 11 | 0.884 | 0.2337 | Yes |
| 3 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.3233 | Yes |
| 4 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 34 | 0.714 | 0.4045 | Yes |
| 5 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.4752 | Yes |
| 6 | ADM | ADM Entrez, Source | adrenomedullin | 96 | 0.523 | 0.5324 | Yes |
| 7 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 228 | 0.365 | 0.5646 | Yes |
| 8 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 329 | 0.291 | 0.5905 | Yes |
| 9 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 433 | 0.249 | 0.6114 | Yes |
| 10 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 658 | 0.195 | 0.6170 | Yes |
| 11 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 673 | 0.190 | 0.6379 | Yes |
| 12 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 682 | 0.188 | 0.6589 | Yes |
| 13 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 908 | 0.156 | 0.6599 | Yes |
| 14 | EPO | EPO Entrez, Source | erythropoietin | 1235 | 0.125 | 0.6497 | No |
| 15 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 1528 | 0.107 | 0.6400 | No |
| 16 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 1598 | 0.103 | 0.6466 | No |
| 17 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 2074 | 0.082 | 0.6203 | No |
| 18 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 2201 | 0.077 | 0.6197 | No |
| 19 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 2668 | 0.063 | 0.5919 | No |
| 20 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 2905 | 0.057 | 0.5808 | No |
| 21 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 3034 | 0.054 | 0.5773 | No |
| 22 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 3097 | 0.052 | 0.5786 | No |
| 23 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 3953 | 0.034 | 0.5181 | No |
| 24 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 4021 | 0.032 | 0.5168 | No |
| 25 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 4159 | 0.030 | 0.5100 | No |
| 26 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 4507 | 0.023 | 0.4865 | No |
| 27 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 4653 | 0.021 | 0.4780 | No |
| 28 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 4825 | 0.018 | 0.4672 | No |
| 29 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 5227 | 0.011 | 0.4383 | No |
| 30 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 5302 | 0.010 | 0.4339 | No |
| 31 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 5905 | 0.001 | 0.3888 | No |
| 32 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 6101 | -0.002 | 0.3743 | No |
| 33 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 6298 | -0.005 | 0.3601 | No |
| 34 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6363 | -0.006 | 0.3559 | No |
| 35 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 6512 | -0.008 | 0.3457 | No |
| 36 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6731 | -0.011 | 0.3306 | No |
| 37 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 6961 | -0.014 | 0.3150 | No |
| 38 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 7101 | -0.017 | 0.3065 | No |
| 39 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 7114 | -0.017 | 0.3076 | No |
| 40 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 7650 | -0.025 | 0.2702 | No |
| 41 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 7989 | -0.031 | 0.2483 | No |
| 42 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 8124 | -0.033 | 0.2419 | No |
| 43 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 8819 | -0.044 | 0.1948 | No |
| 44 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | 0.1362 | No |
| 45 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 9715 | -0.060 | 0.1413 | No |
| 46 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 10930 | -0.089 | 0.0602 | No |
| 47 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | 0.0612 | No |
| 48 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 11237 | -0.097 | 0.0590 | No |
| 49 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 11329 | -0.100 | 0.0636 | No |
| 50 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12255 | -0.140 | 0.0101 | No |
| 51 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 12777 | -0.181 | -0.0083 | No |
| 52 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 12783 | -0.183 | 0.0124 | No |
| 53 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13116 | -0.257 | 0.0170 | No |
