Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | DNA_REPLICATION |
| Enrichment Score (ES) | -0.49214336 |
| Normalized Enrichment Score (NES) | -1.675461 |
| Nominal p-value | 0.0022675737 |
| FDR q-value | 0.09411864 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 735 | 0.179 | -0.0094 | No |
| 2 | TERF2IP | TERF2IP Entrez, Source | telomeric repeat binding factor 2, interacting protein | 832 | 0.165 | 0.0255 | No |
| 3 | EREG | EREG Entrez, Source | epiregulin | 3011 | 0.054 | -0.1244 | No |
| 4 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 3116 | 0.051 | -0.1191 | No |
| 5 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 3157 | 0.051 | -0.1091 | No |
| 6 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 4322 | 0.027 | -0.1898 | No |
| 7 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.1902 | No |
| 8 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 4433 | 0.025 | -0.1852 | No |
| 9 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 5179 | 0.012 | -0.2382 | No |
| 10 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 5310 | 0.010 | -0.2454 | No |
| 11 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 5470 | 0.008 | -0.2554 | No |
| 12 | NBN | NBN Entrez, Source | nibrin | 5580 | 0.006 | -0.2620 | No |
| 13 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.2931 | No |
| 14 | GLI1 | GLI1 Entrez, Source | glioma-associated oncogene homolog 1 (zinc finger protein) | 6332 | -0.005 | -0.3171 | No |
| 15 | PTMS | PTMS Entrez, Source | parathymosin | 6405 | -0.006 | -0.3209 | No |
| 16 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6561 | -0.008 | -0.3303 | No |
| 17 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7386 | -0.021 | -0.3870 | No |
| 18 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.3819 | No |
| 19 | KCTD13 | KCTD13 Entrez, Source | potassium channel tetramerisation domain containing 13 | 7494 | -0.022 | -0.3840 | No |
| 20 | TBRG1 | TBRG1 Entrez, Source | transforming growth factor beta regulator 1 | 7513 | -0.023 | -0.3795 | No |
| 21 | IGHMBP2 | IGHMBP2 Entrez, Source | immunoglobulin mu binding protein 2 | 7514 | -0.023 | -0.3738 | No |
| 22 | TINF2 | TINF2 Entrez, Source | TERF1 (TRF1)-interacting nuclear factor 2 | 7844 | -0.028 | -0.3913 | No |
| 23 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 7902 | -0.029 | -0.3882 | No |
| 24 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 7950 | -0.030 | -0.3840 | No |
| 25 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8469 | -0.038 | -0.4132 | No |
| 26 | REPIN1 | REPIN1 Entrez, Source | replication initiator 1 | 8879 | -0.045 | -0.4324 | No |
| 27 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 9310 | -0.053 | -0.4512 | No |
| 28 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 9642 | -0.059 | -0.4611 | No |
| 29 | WRNIP1 | WRNIP1 Entrez, Source | Werner helicase interacting protein 1 | 9976 | -0.066 | -0.4693 | No |
| 30 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 10281 | -0.072 | -0.4737 | Yes |
| 31 | GTPBP4 | GTPBP4 Entrez, Source | GTP binding protein 4 | 10400 | -0.075 | -0.4635 | Yes |
| 32 | MUTYH | MUTYH Entrez, Source | mutY homolog (E. coli) | 10453 | -0.076 | -0.4478 | Yes |
| 33 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 10679 | -0.082 | -0.4438 | Yes |
| 34 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 10715 | -0.083 | -0.4251 | Yes |
| 35 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.4276 | Yes |
| 36 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.4154 | Yes |
| 37 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 12078 | -0.131 | -0.4458 | Yes |
| 38 | TFAM | TFAM Entrez, Source | transcription factor A, mitochondrial | 12117 | -0.133 | -0.4147 | Yes |
| 39 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 12204 | -0.137 | -0.3861 | Yes |
| 40 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12284 | -0.141 | -0.3559 | Yes |
| 41 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 12414 | -0.149 | -0.3274 | Yes |
| 42 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12704 | -0.173 | -0.3048 | Yes |
| 43 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12819 | -0.188 | -0.2653 | Yes |
| 44 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12846 | -0.192 | -0.2181 | Yes |
| 45 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12952 | -0.209 | -0.1725 | Yes |
| 46 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1205 | Yes |
| 47 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.0634 | Yes |
| 48 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13244 | -0.339 | 0.0074 | Yes |
