Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.6796598 |
| Normalized Enrichment Score (NES) | -2.0142257 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006810082 |
| FWER p-Value | 0.102 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4225 | 0.029 | -0.3040 | No |
| 2 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 4433 | 0.025 | -0.3081 | No |
| 3 | UBC | UBC Entrez, Source | ubiquitin C | 4954 | 0.016 | -0.3398 | No |
| 4 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 5470 | 0.008 | -0.3750 | No |
| 5 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 5994 | 0.000 | -0.4142 | No |
| 6 | UBB | UBB Entrez, Source | ubiquitin B | 6484 | -0.007 | -0.4475 | No |
| 7 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7386 | -0.021 | -0.5056 | No |
| 8 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 7389 | -0.021 | -0.4963 | No |
| 9 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 7902 | -0.029 | -0.5213 | No |
| 10 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.5588 | No |
| 11 | RPS27A | RPS27A Entrez, Source | ribosomal protein S27a | 10266 | -0.072 | -0.6467 | Yes |
| 12 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 10679 | -0.082 | -0.6399 | Yes |
| 13 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10985 | -0.090 | -0.6215 | Yes |
| 14 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11062 | -0.092 | -0.5848 | Yes |
| 15 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.5467 | Yes |
| 16 | UBA52 | UBA52 Entrez, Source | ubiquitin A-52 residue ribosomal protein fusion product 1 | 11223 | -0.096 | -0.5092 | Yes |
| 17 | POLD2 | POLD2 Entrez, Source | polymerase (DNA directed), delta 2, regulatory subunit 50kDa | 12204 | -0.137 | -0.5198 | Yes |
| 18 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 12251 | -0.140 | -0.4590 | Yes |
| 19 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12284 | -0.141 | -0.3964 | Yes |
| 20 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 12293 | -0.142 | -0.3317 | Yes |
| 21 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 12704 | -0.173 | -0.2827 | Yes |
| 22 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12846 | -0.192 | -0.2051 | Yes |
| 23 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13021 | -0.223 | -0.1156 | Yes |
| 24 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | 0.0104 | Yes |
